{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T15:57:16Z","timestamp":1789660636739,"version":"4.0.1"},"reference-count":5,"publisher":"American Veterinary Medical Association (AVMA)","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2024,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>\n                      To describe the clinical presentation, diagnostic findings, and medical management of the first suspected autochthonous case of a dog in the US diagnosed with\n                      <jats:italic>Angiostrongylus vasorum<\/jats:italic>\n                      , the French heartworm.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>ANIMAL<\/jats:title>\n                    <jats:p>A 10-month-old Goldendoodle born in Oregon and residing in Washington State.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CLINICAL PRESENTATION, PROGRESSION, AND PROCEDURES<\/jats:title>\n                    <jats:p>\n                      The dog presented for evaluation of intermittent vomiting and diarrhea. Bloodwork revealed leukocytosis with mild lymphocytosis, monocytosis, eosinophilia, and basophilia. Larvae were detected on a fecal flotation, and fecal PCR confirmed\n                      <jats:italic>A vasorum<\/jats:italic>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>TREATMENT AND OUTCOME<\/jats:title>\n                    <jats:p>Administration of milbemycin oxime PO once a week for 4 weeks was initiated with recommendation to continue monthly treatment at label dose. The patient improved over the course of treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CLINICAL RELEVANCE<\/jats:title>\n                    <jats:p>\n                      This case highlights the clinical and diagnostic findings and medical management of\n                      <jats:italic>A vasorum<\/jats:italic>\n                      , also known as the French heartworm, in a dog in the US. Few cases of\n                      <jats:italic>A vasorum<\/jats:italic>\n                      have been reported in wild foxes in North America, mostly in eastern Canada and 1 within the eastern US. Here we report for the first time an autochthonous case of\n                      <jats:italic>A vasorum<\/jats:italic>\n                      in a domestic dog in the US and the first report of any canid in the western US. This case highlights the importance of considering\n                      <jats:italic>A vasorum<\/jats:italic>\n                      as a differential for respiratory disease, gastrointestinal disease, or inexplicable eosinophilia in canine veterinary patients in the US and raises awareness for veterinary practitioners to incorporate appropriate preventative and diagnostic measures for their canine patients.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.2460\/javma.24.06.0408","type":"journal-article","created":{"date-parts":[[2024,8,2]],"date-time":"2024-08-02T12:44:00Z","timestamp":1722602640000},"page":"1-3","source":"Crossref","is-referenced-by-count":5,"title":["First autochthonous case of Angiostrongylus vasorum in a domestic dog in the United States"],"prefix":"10.2460","volume":"262","author":[{"given":"Laura B. A.","family":"Williams","sequence":"first","affiliation":[{"name":"Department of Veterinary Microbiology and Pathology, Washington Animal Disease Diagnostic Laboratory, College of Veterinary Medicine, Washington State University, Pullman, WA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minden L.","family":"Buswell","sequence":"additional","affiliation":[{"name":"Washington State Department of Agriculture, Olympia, WA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolle A.","family":"Perisho","sequence":"additional","affiliation":[{"name":"Poulsbo Marina Veterinary Clinic, Poulsbo, WA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"Vet Med (Auckl)","first-page":"181","article-title":"Canine angiostrongylosis: recent advances in diagnosis, prevention, and treatment","volume":"5","author":"Di Cesare A","year":"2014","unstructured":"Di Cesare A, Traversa D. Canine angiostrongylosis: recent advances in diagnosis, prevention, and treatment. Vet Med (Auckl). 2014;5:181-192. doi:10.2147\/VMRR.S53641"},{"issue":"6","key":"ref2","series-title":"Can Vet J","first-page":"637","article-title":"First report of Angiostrongylus vasorum (French heartworm) in red foxes (Vulpes vulpes) on Prince Edward Island","volume":"63","author":"Mahjoub HA","year":"2022","unstructured":"Mahjoub HA, Robbins WT, Galeuzzi O,  First report of Angiostrongylus vasorum (French heartworm) in red foxes (Vulpes vulpes) on Prince Edward Island. Can Vet J. 2022;63(6):637-640."},{"issue":"1-2","key":"ref3","series-title":"Vet Parasitol","first-page":"216","article-title":"First report of Angiostrongylus vasorum and Hepatozoon from a red fox (Vulpes vulpes) from West Virginia, USA","volume":"200","author":"Kistler WM","year":"2014","unstructured":"Kistler WM, Brown JD, Allison AB, Nemeth NM, Yabsley MJ. First report of Angiostrongylus vasorum and Hepatozoon from a red fox (Vulpes vulpes) from West Virginia, USA. Vet Parasitol. 2014;200(1-2):216-220. doi:10.1016\/j.vetpar.2013.12.007"},{"issue":"3-4","key":"ref4","series-title":"Vet Parasitol","first-page":"272","article-title":"Assessment of the combination of spinosad and milbemycin oxime in preventing the development of canine Angiostrongylus vasorum infections","volume":"199","author":"B\u00f6hm C","year":"2014","unstructured":"B\u00f6hm C, Schnyder M, Thamsborg SM,  Assessment of the combination of spinosad and milbemycin oxime in preventing the development of canine Angiostrongylus vasorum infections. Vet Parasitol. 2014;199(3-4):272-277. doi:10.1016\/j.vetpar.2013.10.024"},{"issue":"2","key":"ref5","series-title":"Ir Vet J","first-page":"103","article-title":"Clinical signs, diagnosis and treatment of three dogs with angiostrongylosis in Ireland","volume":"57","author":"Brennan SF","year":"2004","unstructured":"Brennan SF, McCarthy G, McAllister H, Bassett H, Jones BR. Clinical signs, diagnosis and treatment of three dogs with angiostrongylosis in Ireland. Ir Vet J. 2004;57(2):103-109. doi:10.1186\/2046-0481-57-2-103"}],"container-title":["Journal of the American Veterinary Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/262\/10\/javma.24.06.0408.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/262\/10\/javma.24.06.0408.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/262\/10\/javma.24.06.0408.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T09:08:43Z","timestamp":1741338523000},"score":1,"resource":{"primary":{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/262\/10\/javma.24.06.0408.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,1]]},"references-count":5,"journal-issue":{"issue":"10"},"URL":"https:\/\/doi.org\/10.2460\/javma.24.06.0408","relation":{},"ISSN":["0003-1488"],"issn-type":[{"value":"0003-1488","type":"print"}],"subject":[],"published":{"date-parts":[[2024,10,1]]}}}