{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T14:15:05Z","timestamp":1790345705059,"version":"4.1.0"},"reference-count":36,"publisher":"American Veterinary Medical Association (AVMA)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2012,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p><jats:bold>Objective<\/jats:bold>\u2014To evaluate the outcome of resection of simultaneous discrete bilateral mobile thyroid gland carcinomas (TGCs) in dogs.<\/jats:p>\n<jats:p><jats:bold>Design<\/jats:bold>\u2014Retrospective case series.<\/jats:p>\n<jats:p><jats:bold>Animals<\/jats:bold>\u201415 dogs with resected simultaneous discrete bilateral mobile TGCs.<\/jats:p>\n<jats:p><jats:bold>Procedures<\/jats:bold>\u2014Medical records (from 1994 to 2010) were searched for dogs with the appropriate diagnosis and treatment. Information collected included signalment, clinical signs, diagnostic test results, tumor mobility (mobile tumor identified by movement \u2265 1 cm in all planes during palpation), complications, adjuvant treatments, and outcome.<\/jats:p>\n<jats:p><jats:bold>Results<\/jats:bold>\u2014Mobile, discrete, bilateral TGCs were removed in all dogs. Among the 15 dogs, complete parathyroidectomies were necessary in 9; parathyroid tissue was reimplanted in 4 and preserved in 2. Complications included hemorrhage and laryngeal nerve trauma, but without serious consequences. Thirteen dogs received calcitriol with or without supplemental calcium after surgery. In the immediate postoperative period, hypocalcemia developed and was corrected in 11 dogs. At the end of the study, 7 dogs continued to receive calcitriol with or without supplemental calcium, and 8 dogs required long-term thyroid hormone treatment. Six dogs received adjuvant chemotherapy. Local tumor recurrence or de novo distant metastasis was not detected at each dog's last follow-up examination. Median survival time was 38.3 months. Three dogs were lost to follow-up, 8 survived (4.3 to 77 months after surgery), and 4 died of unrelated causes.<\/jats:p>\n<jats:p><jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\u2014In dogs with TGCs undergoing bilateral thyroid lobectomies, a successful outcome can be expected, even when parathyroid gland tissue cannot be preserved. The role of adjuvant chemotherapy in treatment outcome was not clearly defined.<\/jats:p>","DOI":"10.2460\/javma.241.1.95","type":"journal-article","created":{"date-parts":[[2012,6,21]],"date-time":"2012-06-21T22:07:23Z","timestamp":1340316443000},"page":"95-103","source":"Crossref","is-referenced-by-count":34,"title":["Outcome following simultaneous bilateral thyroid lobectomy for treatment of thyroid gland carcinoma in dogs: 15 cases (1994\u20132010)"],"prefix":"10.2460","volume":"241","author":[{"given":"Joanne L.","family":"Tuohy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deanna R.","family":"Worley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen J.","family":"Withrow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"Vet Clin North Am Small Anim Pract","first-page":"755","article-title":"Thyroid tumors in dogs and cats","volume":"37","author":"Barber","year":"2007"},{"key":"ref2","series-title":"J Am Anim Hosp Assoc","first-page":"369","article-title":"Thyroid neoplasia of the thyroid gland in the dog\u2014a retrospective study of 16 cases","volume":"17","author":"Birchard","year":"1981"},{"key":"ref3","series-title":"Cancer","first-page":"406","article-title":"Thyroid neoplasms in the dog. 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