{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T12:13:57Z","timestamp":1768479237101,"version":"3.49.0"},"reference-count":41,"publisher":"American Veterinary Medical Association (AVMA)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2012,7,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p><jats:bold>Objective<\/jats:bold>\u2014To determine frequency of antimicrobial drug (AMD) use in dogs within 12 months prior to admission to a veterinary teaching hospital.<\/jats:p>\n<jats:p><jats:bold>Design<\/jats:bold>\u2014Owner survey and medical records review.<\/jats:p>\n<jats:p><jats:bold>Animals<\/jats:bold>\u2014435 dogs admitted to a veterinary teaching hospital.<\/jats:p>\n<jats:p><jats:bold>Procedures<\/jats:bold>\u2014Demographic characteristics and information regarding AMD use in dogs were obtained from medical records and results of surveys completed by owners of dogs.<\/jats:p>\n<jats:p><jats:bold>Results<\/jats:bold>\u2014242 (55.6%) dogs received at least 1 AMD within 12 months prior to hospital admission; 125 (51.7%) of these dogs had a disease of the integument at the time of admission. \u03b2-Lactam AMDs were used more frequently than AMDs of any other class (176\/242 [72.7%] dogs). Three hundred sixty-eight dogs had a medical problem at the time of hospital admission; 225 (61.1%) of these dogs had received at least 1 AMD within 12 months prior to hospital admission. Dogs referred by a veterinarian to the hospital were 2.39 times as likely to have received at least 1 AMD within 30 days prior to hospital admission as were dogs admitted without a referral.<\/jats:p>\n<jats:p><jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\u2014Results indicated AMDs were frequently administered to dogs prior to admission to the teaching hospital. Use of AMDs in animals could be a risk factor for coselection and spread of multidrug-resistant pathogens, and colonization or infection of dogs with such pathogens could have a negative impact on the health of other animals and humans.<\/jats:p>","DOI":"10.2460\/javma.241.2.210","type":"journal-article","created":{"date-parts":[[2012,7,5]],"date-time":"2012-07-05T17:31:43Z","timestamp":1341509503000},"page":"210-217","source":"Crossref","is-referenced-by-count":30,"title":["Antimicrobial drug use in dogs prior to admission to a veterinary teaching hospital"],"prefix":"10.2460","volume":"241","author":[{"given":"Sarah A.","family":"Baker","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joany","family":"Van-Balen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Hillier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Armando E.","family":"Hoet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"Science","first-page":"1050","article-title":"Epidemiology of drug resistance: implications for a post-antimicrobial era","volume":"257","author":"Cohen","year":"1992"},{"key":"ref2","series-title":"Handb Exp Pharmacol","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1007\/978-3-642-10324-7_10","article-title":"Antimicrobial drug resistance","volume":"199","author":"Martinez","year":"2010"},{"key":"ref3","series-title":"J Vet Intern Med","first-page":"617","article-title":"Antimicrobial drug use in veterinary medicine","volume":"19","author":"Morley","year":"2005"},{"key":"ref4","series-title":"J Am Vet Med Assoc","first-page":"694","article-title":"Development of antimicrobial drug resistance in rectal Escherichia coli isolates from dogs hospitalized in an intensive care unit","volume":"229","author":"Ogeer-Gyles","year":"2006"},{"key":"ref5","series-title":"J Am Vet Med Assoc","first-page":"1909","article-title":"Impact of hospitalization and antimicrobial drug administration on antimicrobial susceptibility patterns of commensal Escherichia coli isolated from the feces of horses","volume":"228","author":"Dunowska","year":"2006"},{"key":"ref6","series-title":"Pediatrics","first-page":"856","article-title":"from healthy children living in isolated rural communities: association with cephalosporin use and intrafamilial transmission","volume":"108","author":"Samore","year":"2001"},{"key":"ref7","series-title":"J Antimicrob Chemother","first-page":"645","article-title":"Bacteria with increased mutation frequency and antibiotic resistance are enriched in the commensal flora of patients with high antibiotic usage","volume":"52","author":"Gustafsson","year":"2003"},{"key":"ref8","series-title":"Proc Natl Acad Sci U S A","first-page":"1152","article-title":"The relationship between the volume of antimicrobial consumption in human communities and the frequency of resistance","volume":"9","author":"Austin","year":"1999"},{"key":"ref9","series-title":"Prev Vet Med","first-page":"25","article-title":"Animal and farm influences on the dynamics of antibiotic resistance in faecal Escherichia coli in young dairy calves","volume":"69","author":"Berge","year":"2005"},{"key":"ref10","series-title":"Am J Vet Res","first-page":"988","article-title":"Antimicrobial susceptibility of enteric bacteria recovered from feedlot cattle administered chlortetracycline in feed (Erratum published in Am J Vet Res 2008; 69:1163)","volume":"69","author":"Platt","year":"2008"},{"key":"ref11","series-title":"Antimicrob Agents Chemother","first-page":"520","article-title":"Relationship between quinolone use and emergence of ciprofloxacin-resistant Escherichia coli in bloodstream infections","volume":"3","author":"Pena","year":"1995"},{"key":"ref12","series-title":"Drugs","first-page":"589","article-title":"Antibiotic usage in animals: impact on bacterial resistance and public health","volume":"58","author":"van den Bogaard","year":"1999"},{"key":"ref13","series-title":"J Am Vet Med Assoc","first-page":"411","article-title":"Antimicrobial susceptibilities of Escherichia coli strains from a turkey operation","volume":"221","author":"Altekruse","year":"2002"},{"key":"ref14","series-title":"J Antimicrob Chemother","first-page":"763","article-title":"Antibiotic resistance of faecal Escherichia coli in poultry, poultry farmers and poultry slaughterers","volume":"47","author":"van den Bogaard","year":"2001"},{"key":"ref15","series-title":"J Clin Microbiol","first-page":"1832","article-title":"Transfer of erythromycin resistance from poultry to human clinical strains of Staphylococcus aureus","volume":"38","author":"Khan","year":"2000"},{"key":"ref16","series-title":"Acta Vet Scand","first-page":"189","article-title":"Antibacterial drugs prescribed for dogs and cats in Sweden and Norway 1990\u20131998","volume":"42","author":"Odensvik","year":"2001"},{"key":"ref17","series-title":"Vet Rec","first-page":"259","article-title":"Survey of condition-based prescribing of antimicrobial drugs for dogs at a veterinary teaching hospital","volume":"155","author":"Rantala","year":"2004"},{"key":"ref18","series-title":"J Am Vet Med Assoc","first-page":"553","article-title":"Investigation of antimicrobial use and the impact of antimicrobial use guidelines in a small animal veterinary teaching hospital: 1995\u20132004","volume":"228","author":"Weese","year":"2006"},{"key":"ref19","series-title":"Biostatistics","first-page":"379","article-title":"Unconditional small-sample confidence intervals for the odds ratio","volume":"3","author":"Agresti","year":"2002"},{"key":"ref20","series-title":"Anim Health Res Rev","first-page":"159","article-title":"Antimicrobial resistance in beef and dairy cattle production","volume":"9","author":"Call","year":"2008"},{"key":"ref21","series-title":"Anim Health Res Rev","first-page":"127","article-title":"Antimicrobial use in food and companion animals","volume":"9","author":"Prescott","year":"2008"},{"key":"ref22","series-title":"Curr Opin Microbiol","first-page":"439","article-title":"Antibiotics in animal feed and their role in resistance development","volume":"6","author":"Wegener","year":"2003"},{"key":"ref23","series-title":"Dairy 2007, part IV: reference of dairy cattle health and management practices in the United States, 2007","year":"2009"},{"key":"ref24","article-title":"Beef 2007\u201308, part V: reference of beef cow-calf management practices in the United States, 2007\u201308","year":"2010"},{"key":"ref25","series-title":"Part IV: changes in the U.S. pork industry, 1990\u20132006","year":"2008"},{"key":"ref26","series-title":"Antimicrob Agents Chemother","first-page":"2010","article-title":"Treatment with fluoroquinolones or with beta-lactam-beta-lactamase inhibitor combinations is a risk factor for isolation of extended-spectrum-beta-lactamase-producing Klebsiella species in hospitalized patients","volume":"54","author":"Wener","year":"2010"},{"key":"ref27","series-title":"Clin Infect Dis","first-page":"S187","article-title":"Antimicrobial use and the emergence of antimicrobial resistance with 1Streptococcus pneumoniae in the United States","volume":"33","author":"Doern","year":"2001"},{"key":"ref28","series-title":"FEMS Microbiol Ecol","first-page":"313","article-title":"Changes in fecal microbiota of healthy dogs administered amoxicillin","volume":"71","author":"Gr\u00f8nvold","year":"2010"},{"key":"ref29","series-title":"J Vet Intern Med","first-page":"323","article-title":"Antimicrobial resistance profiles and clonal relatedness of canine and feline Escherichia coli pathogens expressing multidrug resistance in the United States","volume":"24","author":"Shaheen","year":"2010"},{"key":"ref30","series-title":"Microb Drug Resist","first-page":"75","article-title":"Prevalence of antimicrobial resistance in fecal Escherichia coli isolates from stray pet dogs and hospitalized pet dogs in Korea","volume":"16","author":"Nam","year":"2010"},{"key":"ref31","series-title":"J Antimicrob Chemother","first-page":"775","article-title":"Occurrence of antimicrobial resistance in bacteria from diagnostic samples from dogs","volume":"60","author":"Pedersen","year":"2007"},{"key":"ref32","series-title":"J Appl Microbiol","first-page":"1269","article-title":"Prevalence, species distribution and antimicrobial resistance of enterococci isolated from dogs and cats in the United States","volume":"107","author":"Jackson","year":"2009"},{"key":"ref33","series-title":"Vet Microbiol","first-page":"197","article-title":"Prevalence of methicillin-resistant Staphylococcus pseudintermedius isolated from clinical samples of companion animals and equidaes","volume":"136","author":"Ruscher","year":"2009"},{"key":"ref34","series-title":"Vet Rec","first-page":"451","article-title":"Isolation rates of methicillin-resistant Staphylococcus aureus in dogs, cats and horses in Ireland","volume":"166","author":"Abbott","year":"2010"},{"key":"ref35","series-title":"Emerg Infect Dis","first-page":"69","article-title":"Methicillin-resistant and -susceptible Staphylococcus aureus infections in dogs","volume":"16","author":"Faires","year":"2010"},{"key":"ref36","series-title":"Clin Infect Dis","first-page":"26","article-title":"Asymptomatic nasal carriage of mupirocin-resistant, methicillin-resistant Staphylococcus aureus (MRSA) in a pet dog associated with MRSA infection in household contacts","volume":"36","author":"Manian","year":"2003"},{"key":"ref37","series-title":"Vet Microbiol","first-page":"160","article-title":"An outbreak of methicillin-resistant Staphylococcus aureus skin infections resulting from horse to human transmission in a veterinary hospital","volume":"114","author":"Weese","year":"2006"},{"key":"ref38","series-title":"J Am Vet Med Assoc","first-page":"1361","article-title":"Cluster of methicillin-resistant Staphylococcus aureus colonization in a small animal intensive care unit","volume":"231","author":"Weese","year":"2007"},{"key":"ref39","series-title":"Guidelines for veterinary prescription drugs","year":"2010"},{"key":"ref40","series-title":"Appl Environ Microbiol","first-page":"3872","article-title":"Field trial evaluating the influence of prophylactic and therapeutic antimicrobial administration on antimicrobial resistance of fecal Escherichia coli in dairy calves","volume":"72","author":"Berge","year":"2006"},{"key":"ref41","series-title":"Foodborne Pathog Dis","first-page":"99","article-title":"Association between tetracycline consumption and tetracycline resistance in Escherichia coli from healthy Danish slaughter pigs","volume":"6","author":"Vieira","year":"2009"}],"container-title":["Journal of the American Veterinary Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/241\/2\/javma.241.2.210.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/241\/2\/javma.241.2.210.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/241\/2\/javma.241.2.210.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T13:11:51Z","timestamp":1741353111000},"score":1,"resource":{"primary":{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/241\/2\/javma.241.2.210.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7,15]]},"references-count":41,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.2460\/javma.241.2.210","relation":{},"ISSN":["0003-1488"],"issn-type":[{"value":"0003-1488","type":"print"}],"subject":[],"published":{"date-parts":[[2012,7,15]]}}}