{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T14:25:37Z","timestamp":1774880737079,"version":"3.50.1"},"reference-count":18,"publisher":"American Veterinary Medical Association (AVMA)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2013,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p><jats:bold>Objective<\/jats:bold>\u2014To determine the correlation between plasma lactate concentration and base excess at the time of hospital admission and evaluate each variable as a predictor of gastric necrosis or outcome in dogs with gastric dilatation-volvulus (GDV).<\/jats:p>\n<jats:p><jats:bold>Design<\/jats:bold>\u2014Retrospective case series.<\/jats:p>\n<jats:p><jats:bold>Animals<\/jats:bold>\u201478 dogs.<\/jats:p>\n<jats:p><jats:bold>Procedures<\/jats:bold>\u2014For each dog, various data, including plasma lactate concentration and base excess at the time of hospital admission, surgical or necropsy findings, and outcome, were collected from medical records.<\/jats:p>\n<jats:p><jats:bold>Results<\/jats:bold>\u2014Gastric necrosis was identified in 12 dogs at the time of surgery and in 4 dogs at necropsy. Sixty-five (83%) dogs survived to hospital discharge, whereas 13 (17%) dogs died or were euthanized. Of the 65 survivors and 8 nonsurvivors that underwent surgery, gastric necrosis was detected in 8 and 4 dogs, respectively. Via receiver operating characteristic curve analysis, an initial plasma lactate concentration cutoff of 7.4 mmol\/L was 82% accurate for predicting gastric necrosis (sensitivity, 50%; specificity, 88%) and 88% accurate for predicting outcome (sensitivity, 75%; specificity, 89%). Among all dogs, the correlation between initial plasma lactate concentration and base excess was significant, although base excess was a poor discriminator for predicting gastric necrosis or outcome (area under the receiver operating characteristic curve, 0.571 and 0.565, respectively).<\/jats:p>\n<jats:p><jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\u2014In dogs with GDV, plasma lactate concentration at the time of hospital admission was a good predictor of gastric necrosis and outcome. However, despite the correlation between initial base excess and plasma lactate concentration, base excess should not be used for prediction of gastric necrosis or outcome in those patients.<\/jats:p>","DOI":"10.2460\/javma.242.1.54","type":"journal-article","created":{"date-parts":[[2012,12,12]],"date-time":"2012-12-12T19:09:04Z","timestamp":1355339344000},"page":"54-58","source":"Crossref","is-referenced-by-count":67,"title":["Evaluation of plasma lactate concentration and base excess at the time of hospital admission as predictors of gastric necrosis and outcome and correlation between those variables in dogs with gastric dilatation-volvulus: 78 cases (2004\u20132009)"],"prefix":"10.2460","volume":"242","author":[{"given":"Kari A.","family":"Santoro Beer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca S.","family":"Syring","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth J.","family":"Drobatz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"J Am Vet Med Assoc","first-page":"49","article-title":"Plasma lactate concentration as a predictor of gastric necrosis and survival among dogs with gastric dilatation-volvulus: 102 cases (1995\u20131998)","volume":"215","author":"de Papp","year":"1999"},{"key":"ref2","series-title":"J Am Vet Med Assoc","first-page":"1855","article-title":"Factors associated with perioperative mortality in dogs with surgically managed gastric dilatation-volvulus: 137 cases (1988\u20131993)","volume":"208","author":"Brourman","year":"1996"},{"key":"ref3","series-title":"J Am Vet Med Assoc","first-page":"460","article-title":"Canine gastric dilatation\/volvulus syndrome in a veterinary critical care 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outcome and development of perioperative complications in dogs undergoing surgery because of gastric dilatation-volvulus: 166 cases (1992\u20132003)","volume":"229","author":"Beck","year":"2006"}],"container-title":["Journal of the American Veterinary Medical 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