{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T04:24:08Z","timestamp":1768278248786,"version":"3.49.0"},"reference-count":37,"publisher":"American Veterinary Medical Association (AVMA)","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2013,5,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p><jats:bold>Case Description<\/jats:bold>\u2014A 40.3-kg (88.7-lb) 6-year-old spayed female Labrador Retriever was evaluated because of acute unilateral epistaxis.<\/jats:p>\n<jats:p><jats:bold>Clinical Findings<\/jats:bold>\u2014During the initial evaluation of the dog, systemic hypertension and a left adrenal gland mass were detected. The left adrenal gland mass was surgically removed; results of histologic examination of the mass indicated it was a pheochromocytoma. Ten months later, the dog was evaluated because of persistent systemic hypertension and development of polyuria, polydipsia, and excessive panting. Abdominal ultrasonography revealed a mass in the cranial aspect of the right adrenal gland; results of MRI suggested the mass was a malignant tumor.<\/jats:p>\n<jats:p><jats:bold>Treatment and Outcome<\/jats:bold>\u2014Epistaxis resolved after treatment and resolution of severe systemic hypertension. A partial right adrenalectomy was performed to remove the right adrenal gland mass. Results of histologic examination of the mass indicated it was a well-differentiated carcinoma of the cortex of the adrenal gland. Results of ACTH stimulation tests after surgery indicated the dog had adequate adrenal gland function.<\/jats:p>\n<jats:p><jats:bold>Clinical Relevance<\/jats:bold>\u2014Partial adrenalectomy may be a safe and feasible treatment option to preserve adrenal gland function in dogs with small eccentrically located adrenal gland masses, particularly for dogs that have undergone removal of the contralateral adrenal gland.<\/jats:p>","DOI":"10.2460\/javma.242.10.1398","type":"journal-article","created":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T18:27:56Z","timestamp":1367432876000},"page":"1398-1404","source":"Crossref","is-referenced-by-count":5,"title":["Adrenal gland function in a dog following unilateral complete adrenalectomy and contralateral partial adrenalectomy"],"prefix":"10.2460","volume":"242","author":[{"given":"Ross N.","family":"Larson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chad W.","family":"Schmiedt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica","family":"Lawrence","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth W.","family":"Howerth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shannon P.","family":"Holmes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan W.","family":"Grey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"Changes in ultrasonographic appearance of adrenal glands in dogs with pituitary-dependent hyperadrenocorticism treated with trilostane","first-page":"682","volume":"44","author":"Mantis","year":"2003"},{"key":"ref2","series-title":"Dynamic contrast enhanced MRI in the differential diagnosis of adrenal adenomas and malignant adrenal masses","first-page":"154","volume":"65","author":"Inan","year":"2008"},{"key":"ref3","series-title":"CT and MR imaging of the adrenal glands in cortisol-secreting tumors","first-page":"2923","volume":"31","author":"Lumachi","year":"2011"},{"key":"ref4","series-title":"Magnetic resonance imaging differentiation of adrenal masses at 1.5 T: T2-weighted images, chemical shift imaging, and Gd-DTPA dynamic studies","first-page":"163","volume":"4","author":"Slapa","year":"1996"},{"key":"ref5","series-title":"Multiple endocrine neoplasias in a dog: corticotrophic tumour, bilateral adrenocortical tumours, and pheochromocytoma","first-page":"56","volume":"20","author":"Thuroczy","year":"1998"},{"key":"ref6","series-title":"Veterinary diagnostic imaging. 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Shoulder mass in a dog with lameness","first-page":"511","volume":"38","author":"Boes","year":"2009"},{"key":"ref33","series-title":"Hypertension: a risk factor associated with weight status in dogs","first-page":"2011S","volume":"136","author":"Montoya","year":"2006"},{"key":"ref34","series-title":"Obesity in dogs and cats: a metabolic and endocrine disorder","first-page":"221","volume":"40","author":"Zoran","year":"2010"},{"key":"ref35","series-title":"White-coat effect on systemic blood pressure in retired racing Greyhounds","first-page":"861","volume":"25","author":"Marino","year":"2011"},{"key":"ref36","series-title":"Evaluation of the white-coat effect in cats","first-page":"134","volume":"13","author":"Belew","year":"1999"},{"key":"ref37","series-title":"Endocrine hypertension in small animals","first-page":"335","volume":"40","author":"Reusch","year":"2010"}],"container-title":["Journal of the American Veterinary Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/242\/10\/javma.242.10.1398.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/242\/10\/javma.242.10.1398.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/242\/10\/javma.242.10.1398.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T11:35:50Z","timestamp":1741347350000},"score":1,"resource":{"primary":{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/242\/10\/javma.242.10.1398.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5,15]]},"references-count":37,"journal-issue":{"issue":"10"},"URL":"https:\/\/doi.org\/10.2460\/javma.242.10.1398","relation":{},"ISSN":["0003-1488"],"issn-type":[{"value":"0003-1488","type":"print"}],"subject":[],"published":{"date-parts":[[2013,5,15]]}}}