{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T00:34:06Z","timestamp":1792542846561,"version":"4.5.0"},"reference-count":72,"publisher":"American Veterinary Medical Association (AVMA)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2013,8,1]]},"abstract":"Abstract<\/jats:title>\n \n Objective<\/jats:bold>\n \u2014To compare ultrasonographic and histologic examination findings for eyes of animals with ocular diseases.\n <\/jats:p>\n \n Design<\/jats:bold>\n \u2014Retrospective case series.\n <\/jats:p>\n \n Animals<\/jats:bold>\n \u2014116 eyes of 113 animals examined at 2 facilities.\n <\/jats:p>\n \n Procedures<\/jats:bold>\n \u2014Diseased eyes of animals were examined by means of ultrasonography, removed via enucleation or exenteration, then histologically examined. Ultrasonographic images and histopathologic slides were evaluated, and diseases of eyes were identified with each of those methods and allocated to various categories. For each disease category, agreement between results of ultrasonography and those of histologic examination was assessed via determination of \u03ba statistic values.\n <\/jats:p>\n \n Results<\/jats:bold>\n \u2014Tests had good agreement for identification of iris or ciliary body neoplasia. Overall, intraocular neoplasia was not detected via ultrasonography for only 2 of 31 eyes with histologically detected neoplasia. Hemorrhagic or inflammatory changes were misinterpreted as neoplasia for 8 of 37 (22%) eyes. Tests had moderate to acceptable agreement for identification of retinal detachment. Retinal detachment was not detected by means of ultrasonography for 14 of 38 (37%) eyes with that diagnosis determined via histologic examination at one of the facilities (primarily in eyes with intraocular hemorrhage); however, retinal detachment was not identified via histologic examination for 6 of 38 (16%) eyes with that diagnosis determined via ultrasonography at the other facility.\n <\/jats:p>\n \n Conclusions and Clinical Relevance<\/jats:bold>\n \u2014Agreement between tests evaluated in this study was clinically satisfactory for identification of intraocular neoplasia. Typically, diseases were misdiagnosed via ultrasonography for eyes with poor image contrast. Because determination of ultrasonographic diagnoses of retinal detachment and intraocular neoplasm may be of prognostic importance, performance of additional ultrasonographic techniques may be indicated.\n <\/jats:p>","DOI":"10.2460\/javma.243.3.376","type":"journal-article","created":{"date-parts":[[2013,7,18]],"date-time":"2013-07-18T15:57:43Z","timestamp":1374163063000},"page":"376-388","source":"Crossref","is-referenced-by-count":23,"title":["Comparison of ultrasonography and histologic examination for identification of ocular diseases of animals: 113 cases (2000\u20132010)"],"prefix":"10.2460","volume":"243","author":[{"given":"Nicolin S.","family":"Gallhoefer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellison","family":"Bentley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maja","family":"Ruetten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Grest","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Haessig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick R.","family":"Kircher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard R.","family":"Dubielzig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernhard M.","family":"Spiess","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon A.","family":"Pot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"Veterinary ophthalmology","first-page":"507","article-title":"Ophthalmic examination and diagnostics part 3: diagnostic ultrasonography","author":"Dietrich","year":"2007"},{"key":"ref2","series-title":"Vet Clin North Am Equine Pract","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1016\/j.cveq.2004.04.004","article-title":"Ophthalmic imaging","volume":"20","author":"Ramirez","year":"2004"},{"key":"ref3","series-title":"J Am Vet Med Assoc","doi-asserted-by":"publisher","first-page":"671","DOI":"10.2460\/javma.230.5.671","article-title":"Assessment of ultrasonography and computed tomography for the evaluation of unilateral orbital disease in dogs","volume":"230","author":"Boroffka","year":"2007"},{"key":"ref4","series-title":"Tierarztl Prax","first-page":"481","article-title":"Sonographic diagnosis (B-mode technique) for the eyes in horses. 1. 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Pract","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1016\/j.cveq.2004.04.004","article-title":"Ophthalmic imaging","volume":"20","author":"Ramirez","year":"2004"},{"key":"ref3","series-title":"J Am Vet Med Assoc","doi-asserted-by":"publisher","first-page":"671","DOI":"10.2460\/javma.230.5.671","article-title":"Assessment of ultrasonography and computed tomography for the evaluation of unilateral orbital disease in dogs","volume":"230","author":"Boroffka","year":"2007"},{"key":"ref4","series-title":"Tierarztl Prax","first-page":"481","article-title":"Sonographic diagnosis (B-mode technique) for the eyes in horses. 1. 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Pathological cases","volume":"23","author":"Mettenleiter","year":"1995"},{"key":"ref13","series-title":"Atlas der Ultraschalluntersuchung beim Pferd","article-title":"Atlas der Ultraschalluntersuchung beim Pferd","author":"Wollanke","year":"2011"},{"key":"ref14","series-title":"Equine diagnostic ultrasonography","first-page":"637","article-title":"Equine diagnostic ocular ultrasonography","author":"Wilkie","year":"1998"},{"key":"ref15","series-title":"Am J Vet Res","first-page":"898","article-title":"Ultrasonographic and biometric evaluation of the eye and orbit of dogs","volume":"50","author":"Cottrill","year":"1989"},{"key":"ref16","series-title":"Equine ophthalmology","first-page":"37","article-title":"Equine ocular examination: routine and advanced diagnostic techniques","author":"Gilger","year":"2011"},{"key":"ref17","series-title":"BSAVA manual of canine and feline 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