{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T08:30:43Z","timestamp":1769848243956,"version":"3.49.0"},"reference-count":18,"publisher":"American Veterinary Medical Association (AVMA)","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2016,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p><jats:bold>CASE DESCRIPTION<\/jats:bold> A 1-year-old castrated male dog residing in Indiana was examined because of intermittent vomiting of 4 months' duration.<\/jats:p>\n<jats:p><jats:bold>CLINICAL FINDINGS<\/jats:bold> The dog's condition did not resolve with medication. Diagnostic imaging revealed a possible partial obstruction at the ileocecal junction. An exploratory laparotomy was performed. The jejunum contained diffusely distributed, nodular, intramural lesions; 2 biopsy specimens were collected from representative lesions. The pancreas was grossly swollen, and pancreatitis was presumed present. No other abnormalities were observed in the abdomen. Histologic examination of the submitted biopsy specimens revealed infection with <jats:italic>Heterobilharzia americana.<\/jats:italic><\/jats:p>\n<jats:p><jats:bold>TREATMENT AND OUTCOME<\/jats:bold> After diagnosis, the dog was treated with fenbendazole suspension (48 mg\/kg [21.8 mg\/lb], PO, q 24 h) for 10 days. This treatment was subsequently repeated 11 and 80 days later. One week after the end of the last fenbendazole treatment, several <jats:italic>H americana<\/jats:italic> eggs were detected in a fecal sample via saline sedimentation, and the dog was given praziquantel (25 mg\/kg [11.4 mg\/lb], PO, q 8 h) for 2 days. No gastrointestinal signs were evident 4 months after that treatment.<\/jats:p>\n<jats:p><jats:bold>CLINICAL RELEVANCE<\/jats:bold> The dog described in this report was the first autochthonous canine case of <jats:italic>H americana<\/jats:italic> infection in Indiana, to the authors' knowledge; this case has confirmed that the distribution of this parasite in the Midwestern United States is broader than previously known. Increased awareness of the distribution of <jats:italic>H americana<\/jats:italic> should aid veterinarians in early, noninvasive diagnosis and appropriate treatment of affected animals. Repeated treatments and recheck fecal examinations may be necessary when managing these cases. 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