{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T02:44:58Z","timestamp":1777430698849,"version":"3.51.4"},"reference-count":33,"publisher":"American Veterinary Medical Association (AVMA)","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2016,11,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p><jats:bold>CASE DESCRIPTION<\/jats:bold> 5 dogs were examined because of clinical signs of myelopathy, including signs of pain associated with the spinal region and rapidly progressive neurologic deficits.<\/jats:p>\n<jats:p><jats:bold>CLINICAL FINDINGS<\/jats:bold> In all dogs, results of MRI were consistent with spinal epidural empyema. Concurrent infectious processes were identified at adjacent or distant sites in all dogs, including diskospondylitis, prostatitis, dermatitis, paraspinal infection following a penetrating injury, urinary tract infection, and pyothorax. Bacteria were isolated from 3 dogs; <jats:italic>Escherichia coli<\/jats:italic> was isolated from blood, urine, and prostatic wash samples from 1 dog; a <jats:italic>Pasteurella<\/jats:italic> sp was isolated from a percutaneous aspirate from an adjacent infected wound in a second dog; and a <jats:italic>Corynebacterium<\/jats:italic> sp was isolated from a thoracic fluid sample from a third dog. For the remaining 2 dogs, results of bacterial culture were negative.<\/jats:p>\n<jats:p><jats:bold>TREATMENT AND OUTCOME<\/jats:bold> All dogs showed clinical improvement within 2 weeks after initiation of antimicrobial treatment, and all had an excellent long-term outcome.<\/jats:p>\n<jats:p><jats:bold>CLINICAL RELEVANCE<\/jats:bold> In dogs, spinal epidural empyema has previously been regarded as a surgical emergency. Findings for dogs in the present report suggested that, as is the case for humans, selected dogs with spinal epidural empyema may be successfully managed with medical treatment alone.<\/jats:p>","DOI":"10.2460\/javma.249.10.1180","type":"journal-article","created":{"date-parts":[[2016,11,8]],"date-time":"2016-11-08T13:30:01Z","timestamp":1478611801000},"page":"1180-1186","source":"Crossref","is-referenced-by-count":23,"title":["Medical management of spinal epidural empyema in five dogs"],"prefix":"10.2460","volume":"249","author":[{"given":"Susana R. 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abscess","volume":"164","author":"Siddiq","year":"2004"},{"key":"ref7","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"919","DOI":"10.1227\/01.NEU.0000356972.97356.C5","article-title":"Management of a spontaneous spinal epidural abscess: a single-center 10-year experience","volume":"65","author":"Karikari","year":"2009"},{"key":"ref8","series-title":"Eur Spine J","first-page":"67","article-title":"A retrospective study of surgical and conservative treatment for spinal extradural abscess","volume":"9","author":"Grieve","year":"2009"},{"key":"ref9","series-title":"J Infection","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1053\/jinf.2002.1013","article-title":"Spinal epidural abscess\u2014experience with 46 patients and evaluation of prognostic factors","volume":"45","author":"Tang","year":"2002"},{"key":"ref10","series-title":"J Neurosurg 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Ultrasound","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1111\/j.1740-8261.2008.00339.x","article-title":"Magnetic resonance imaging features of spinal epidural empyema in five dogs","volume":"49","author":"De Stefani","year":"2008"},{"key":"ref14","series-title":"J Am Anim Hosp Assoc","doi-asserted-by":"publisher","first-page":"305","DOI":"10.5326\/15473317-34-4-305","article-title":"Spinal epidural empyema in two dogs","volume":"34","author":"Dewey","year":"1998"},{"key":"ref15","series-title":"J Feline Med Surg","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1016\/j.jfms.2007.01.004","article-title":"Successful treatment of cervical spinal epidural empyema secondary to grass awn migration in a cat","volume":"9","author":"Granger","year":"2007"},{"key":"ref16","series-title":"J Vet Emerg Crit Care","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1111\/j.1476-4431.1998.tb00127.x","article-title":"Suspected spinal epidural empyema and associated 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dogs","volume":"35","author":"Lavely","year":"2006"},{"key":"ref21","series-title":"J Am Anim Hosp Assoc","doi-asserted-by":"publisher","first-page":"149","DOI":"10.5326\/0380149","article-title":"Suspected paraspinal abscess and spinal epidural empyema in a dog","volume":"38","author":"Cherrone","year":"2002"},{"key":"ref22","series-title":"Vet Radiol Ultrasound","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1111\/j.1740-8261.2009.01535.x","article-title":"Magnetic resonance imaging features of paraspinal infection of the dog and cat","volume":"50","author":"Holloway","year":"2009"},{"key":"ref23","series-title":"Clin Orthop Relat Res","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1097\/01.blo.0000183089.37768.2d","article-title":"Spinal epidural abscess: early clinical outcome in patients treated medically","volume":"439","author":"Savage","year":"2005"},{"key":"ref24","series-title":"Vet Rec","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1136\/vr.b4829","article-title":"Spinal osteomyelitis and epidural empyema in a dog due to migrating conifer material","volume":"166","author":"Sutton","year":"2010"},{"key":"ref25","series-title":"Can Vet J","first-page":"595","article-title":"A case of canine discospondylitis and epidural empyema due to Salmonella species","volume":"54","author":"Plessas","year":"2013"},{"key":"ref26","series-title":"J Vet Intern Med","doi-asserted-by":"publisher","first-page":"1318","DOI":"10.1111\/jvim.12183","article-title":"Intervertebral disk degeneration in dogs: consequences, diagnosis, treatment, and future directions","volume":"27","author":"Jeffery","year":"2013"},{"key":"ref27","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"859","DOI":"10.1227\/00006123-198706000-00007","article-title":"The pathogenesis of spinal epidural abscess: a pathophysiological model in the rabbit","volume":"20","author":"Feldenzer","year":"1987"},{"key":"ref28","series-title":"Neurology","doi-asserted-by":"publisher","first-page":"1747","DOI":"10.1212\/WNL.37.11.1747","article-title":"Cervical epidural abscess","volume":"37","author":"Lasker","year":"1987"},{"key":"ref29","series-title":"N Engl J Med","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1056\/NEJM197509042931001","article-title":"Spinal epidural abscess","volume":"293","author":"Baker","year":"1975"},{"key":"ref30","series-title":"J Am Anim Hosp Assoc","first-page":"1841","article-title":"Analysis of cerebrospinal fluid from the cerebellomedullary and lumbar cisterns of dogs with focal neurological disease: 145 cases (1985\u20131987)","volume":"196","author":"Thomson","year":"1990"},{"key":"ref31","series-title":"Eur Spine J","doi-asserted-by":"publisher","first-page":"2787","DOI":"10.1007\/s00586-013-2850-1","article-title":"Spinal infection: state of the art and management 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