{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T15:36:10Z","timestamp":1792856170973,"version":"4.5.0"},"reference-count":34,"publisher":"American Veterinary Medical Association (AVMA)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2017,2,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p><jats:bold>OBJECTIVE<\/jats:bold> To evaluate the effect of anesthesia-associated hypotension on final motor and urinary function in paraplegic dogs without nociception that underwent hemilaminectomy because of acute, severe thoracolumbar intervertebral disk herniation (IVDH).<\/jats:p>\n<jats:p><jats:bold>DESIGN<\/jats:bold> Retrospective case series.<\/jats:p>\n<jats:p><jats:bold>ANIMALS<\/jats:bold> 56 paraplegic dogs with acute thoracolumbar IVDH and absent nociception.<\/jats:p>\n<jats:p><jats:bold>PROCEDURES<\/jats:bold> Medical records were reviewed, and signalment, history, anesthetic details, and results of serial neurologic assessments performed for at least 4 weeks after surgery were recorded. Motor function was retrospectively scored with a 5-point scale, and urinary function was scored with a 3-point scale. Hypotension was defined as MAP \u2264 60 mm Hg or SAP \u2264 80 mm Hg for at least 2 consecutive readings 5 minutes apart. Associations between hypotension and outcome were assessed by use of the Fisher exact test.<\/jats:p>\n<jats:p><jats:bold>RESULTS<\/jats:bold> Thirty-three (59%) patients experienced hypotension during anesthesia. Thirty-four (61%) patients (20\/33 with and 14\/23 without hypotension) regained ambulation. Whether dogs regained motor or urinary function was not significantly associated with the occurrence of hypotension (<jats:italic>P<\/jats:italic> = 0.35 and <jats:italic>P<\/jats:italic> = 0.86, respectively), the duration of hypotension (<jats:italic>P<\/jats:italic> = 0.213 and <jats:italic>P<\/jats:italic> = 0.274), or the lowest blood pressure recorded (<jats:italic>P<\/jats:italic> = 0.556 and <jats:italic>P<\/jats:italic> = 0.699).<\/jats:p>\n<jats:p><jats:bold>CONCLUSIONS AND CLINICAL RELEVANCE<\/jats:bold> For this group of dogs undergoing hemilaminectomy because of acute, severe thoracolumbar IVDH, anesthesia-associated hypotension was not significantly associated with whether dogs regained motor or urinary function after surgery. However, normotension should be the goal in all patients with spinal cord injuries, especially patients undergoing general anesthesia.<\/jats:p>","DOI":"10.2460\/javma.250.4.417","type":"journal-article","created":{"date-parts":[[2017,2,6]],"date-time":"2017-02-06T15:03:18Z","timestamp":1486393398000},"page":"417-423","source":"Crossref","is-referenced-by-count":20,"title":["Effect of anesthesia-associated hypotension on neurologic outcome in dogs undergoing hemilaminectomy because of acute, severe thoracolumbar intervertebral disk herniation: 56 cases (2007\u20132013)"],"prefix":"10.2460","volume":"250","author":[{"given":"Alexandra","family":"Dixon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy E.","family":"Fauber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"J Vet Med","first-page":"22","article-title":"Anesthesia-related hypotension in a small-animal practice","volume":"101","author":"Gordon","year":"2006"},{"key":"ref2","series-title":"J Vet Med A Physiol Pathol Clin Med","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1111\/j.1439-0442.2007.00987.x","article-title":"Normal values and incidence of cardiorespiratory complications in dogs during general anaesthesia. 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