{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T18:52:36Z","timestamp":1777661556190,"version":"3.51.4"},"reference-count":21,"publisher":"American Veterinary Medical Association (AVMA)","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2017,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p><jats:bold>OBJECTIVE<\/jats:bold> To determine the anatomic location and clinical signs of thymoma in goats and long-term outcomes in a subset of goats treated by tumor excision.<\/jats:p>\n<jats:p><jats:bold>DESIGN<\/jats:bold> Retrospective case series.<\/jats:p>\n<jats:p><jats:bold>ANIMALS<\/jats:bold> 13 goats with a histologic diagnosis of thymoma at the Cornell University Hospital for Animals between 1990 and 2014.<\/jats:p>\n<jats:p><jats:bold>PROCEDURES<\/jats:bold> Medical records of goats with thymoma were reviewed and data were evaluated regarding signalment, clinical signs, diagnostic imaging results, thymoma size, treatment, and outcome. Follow-up information was obtained via contact with the owners and review of medical records.<\/jats:p>\n<jats:p><jats:bold>RESULTS<\/jats:bold> 8 goats had a mediastinal mass, 4 had a palpable ventral cervical mass, and 1 had both types of masses. Median age at the time of diagnosis was 9.5 years (range, 3 to 12 years). Goats with a mediastinal mass had respiratory distress or marked tachypnea. Six goats were treated surgically, including all 5 with a ventral cervical mass. All 5 goats with a ventral cervical mass survived with no tumor recurrence for \u2265 1 year after excision. Only 2 goats with a mediastinal mass survived to hospital discharge.<\/jats:p>\n<jats:p><jats:bold>CONCLUSIONS AND CLINICAL RELEVANCE<\/jats:bold> Results suggested that the prognosis for goats following excision of ventral cervical thymomas was favorable, whereas goats with mediastinal thymomas appeared more likely to have severe clinical signs and a guarded prognosis.<\/jats:p>","DOI":"10.2460\/javma.251.7.829","type":"journal-article","created":{"date-parts":[[2017,10,2]],"date-time":"2017-10-02T14:00:38Z","timestamp":1506952838000},"page":"829-834","source":"Crossref","is-referenced-by-count":16,"title":["Clinical features, treatment, and outcome in goats with thymomas: 13 cases (1990\u20132014)"],"prefix":"10.2460","volume":"251","author":[{"given":"Jacqueline A.","family":"Hill","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan L.","family":"Fubini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard P.","family":"Hackett","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"J Am Vet Med Assoc","first-page":"1007","article-title":"Thymoma in dogs: 23 cases (1980\u20131992)","volume":"205","author":"Atwater","year":"1994"},{"key":"ref2","series-title":"Natl Cancer Inst Monogr","first-page":"121","article-title":"Hematopoietic neoplasms of slaughter animals","volume":"32","author":"Migaki","year":"1969"},{"key":"ref3","series-title":"Cancer Res","first-page":"1146","article-title":"Tumors of the thymus in cattle, sheep, and pigs","volume":"29","author":"Sandison","year":"1969"},{"key":"ref4","series-title":"Cancer","doi-asserted-by":"publisher","first-page":"1074","DOI":"10.1002\/1097-0142(19850301)55:5<1074::AID-CNCR2820550524>3.0.CO;2-T","article-title":"Thymoma: a comparative study of clinical stages, histologic features, and survival in 200 cases","volume":"55","author":"Verley","year":"1985"},{"key":"ref5","series-title":"Am J Surg Pathol","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1097\/00000478-200101000-00012","article-title":"Clinical and functional significance of WHO classification on human thymic epithelial neoplasms: a study of 146 consecutive tumors","volume":"25","author":"Okumura","year":"2001"},{"key":"ref6","series-title":"J Am Vet Med Assoc","doi-asserted-by":"publisher","first-page":"1186","DOI":"10.2460\/javma.232.8.1186","article-title":"Results of excision of thymoma in cats and dogs: 20 cases (1984\u20132005)","volume":"232","author":"Zitz","year":"2008"},{"key":"ref7","series-title":"J Am Vet Med Assoc","doi-asserted-by":"publisher","first-page":"1448","DOI":"10.2460\/javma.243.10.1448","article-title":"Clinical features, treatment options, and outcome in dogs with thymoma: 116 cases (1999\u20132010)","volume":"243","author":"Robat","year":"2013"},{"key":"ref8","series-title":"Vet Pathol","doi-asserted-by":"publisher","first-page":"668","DOI":"10.1177\/0300985812471544","article-title":"One hundred two tumors in 100 goats (1987\u20132011)","volume":"50","author":"L\u00f6hr","year":"2013"},{"key":"ref9","series-title":"Vet Pathol","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1177\/030098587801500202","article-title":"High prevalence of thymoma in the dairy goat. Report of seventeen cases","volume":"15","author":"Hadlow","year":"1978"},{"key":"ref10","series-title":"Small animal clinical oncology","first-page":"530","article-title":"Miscellaneous tumors: thymoma","author":"Withrow","year":"1996"},{"key":"ref11","series-title":"J Am Anim Hosp Assoc","first-page":"63","article-title":"Thymoma and acquired myasthenia gravis in the dog: a case report and review of 13 additional cases","volume":"28","author":"Klebanow","year":"1992"},{"key":"ref12","series-title":"Can Vet J","first-page":"267","article-title":"Congestive heart failure associated with thymoma in two Nubian goats","volume":"26","author":"Rostkowski","year":"1985"},{"key":"ref13","series-title":"Can Vet J","first-page":"165","article-title":"Metastatic thymoma in a goat","volume":"37","author":"Olchowy","year":"1996"},{"key":"ref14","series-title":"Vet Rec","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1136\/vr.139.4.94","article-title":"Clinical megaoesophagus in a goat with thymoma","volume":"139","author":"Parish","year":"1996"},{"key":"ref15","series-title":"J Am Anim Hosp Assoc","doi-asserted-by":"publisher","first-page":"489","DOI":"10.5326\/15473317-37-5-489","article-title":"Radiation therapy in the treatment of canine and feline thymomas: a retrospective study (1985\u20131999)","volume":"37","author":"Smith","year":"2001"},{"key":"ref16","series-title":"Crit Rev Oncol Hematol","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/j.critrevonc.2007.04.005","article-title":"Management of thymomas","volume":"65","author":"Wright","year":"2008"},{"key":"ref17","series-title":"Semin Thorac Cardiovasc Surg","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1053\/j.semtcvs.2004.12.001","article-title":"Surgical treatment of thymic tumors","volume":"17","author":"Wright","year":"2005"},{"key":"ref18","series-title":"Small animal radiology and ultrasonography","first-page":"25","article-title":"The thorax","author":"Burk","year":"2003"},{"key":"ref19","series-title":"Textbook of veterinary anatomy","first-page":"627","article-title":"The head and ventral cervical of the ruminants","author":"Dyce","year":"2002"},{"key":"ref20","series-title":"Textbook of veterinary anatomy","first-page":"403","article-title":"The thorax of the carnivores","author":"Dyce","year":"2002"},{"key":"ref21","series-title":"Vet Clin North Am Small Anim Pract","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1016\/S0195-5616(85)50034-0","article-title":"Canine thymoma","volume":"15","author":"Aronsohn","year":"1985"}],"container-title":["Journal of the American Veterinary Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/251\/7\/javma.251.7.829.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/251\/7\/javma.251.7.829.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/251\/7\/javma.251.7.829.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T11:57:25Z","timestamp":1741348645000},"score":1,"resource":{"primary":{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/251\/7\/javma.251.7.829.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10,1]]},"references-count":21,"journal-issue":{"issue":"7"},"URL":"https:\/\/doi.org\/10.2460\/javma.251.7.829","relation":{},"ISSN":["0003-1488"],"issn-type":[{"value":"0003-1488","type":"print"}],"subject":[],"published":{"date-parts":[[2017,10,1]]}}}