{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T12:07:40Z","timestamp":1787314060508,"version":"build-2736575974"},"reference-count":23,"publisher":"American Veterinary Medical Association (AVMA)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2018,7,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:bold>OBJECTIVE<\/jats:bold>\n                    To characterize and investigate potential associations between causes of pleural effusion and various clinical factors in a large cohort of affected cats.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>DESIGN<\/jats:bold>\n                    Retrospective case series with nested cross-sectional study.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>ANIMALS<\/jats:bold>\n                    380 client-owned cats with a diagnosis of pleural effusion from January 1, 2009, through July 14, 2014, for which the cause of pleural effusion had been fully investigated.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>PROCEDURES<\/jats:bold>\n                    Electronic medical records were reviewed and data collected regarding cat characteristics, clinical signs, cause of pleural effusion, treatment, and survival status at discharge from the hospital. Variables were examined for associations with causes of pleural effusion.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>RESULTS<\/jats:bold>\n                    87 (22.9%) cats died or were euthanized before discharge from the hospital. Congestive heart failure (CHF) was the most common cause (155 [40.8%]) of pleural effusion, followed by neoplasia (98 [25.8%]). Other causes included pyothorax, idiopathic chylothorax, trauma, feline infectious peritonitis, and nontraumatic diaphragmatic hernia. Cats with trauma or feline infectious peritonitis were significantly younger than those with CHF or neoplasia. Cats with lymphoma were significantly younger than those with carcinoma. Cats with CHF had a significantly lower rectal temperature at hospital admission (mean \u00b1 SD, 36.9 \u00b1 1.2\u00b0C [98.4 \u00b1 2.2\u00b0F]) than did cats with pleural effusion from other causes (37.9 \u00b1 1.2\u00b0C [100.2 \u00b1 2.2\u00b0F]).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>CONCLUSIONS AND CLINICAL RELEVANCE<\/jats:bold>\n                    Cats with pleural effusion in this study had a poor prognosis; CHF and neoplasia were common causes. Age and hypothermia may be helpful to raise the index of suspicion for certain underlying causes of pleural effusion in cats.\n                  <\/jats:p>","DOI":"10.2460\/javma.253.2.181","type":"journal-article","created":{"date-parts":[[2018,7,2]],"date-time":"2018-07-02T08:47:20Z","timestamp":1530521240000},"page":"181-187","source":"Crossref","is-referenced-by-count":36,"title":["Characterization of and factors associated with causes of pleural effusion in cats"],"prefix":"10.2460","volume":"253","author":[{"given":"Marina Dom\u00ednguez","family":"Ruiz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florence","family":"Vessi\u00e8res","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillaume R.","family":"Ragetly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan 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Surg","doi-asserted-by":"publisher","first-page":"847","DOI":"10.1016\/j.jfms.2009.04.005","article-title":"A new approach to pleural effusion in cats: markers for distinguishing transudates from exudates","volume":"11","author":"Zoia","year":"2009"},{"key":"ref8","series-title":"Vet Clin Pathol","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1111\/j.1939-165X.1999.tb01065.x","article-title":"Sensitivity and specificity of cytologic evaluation in the diagnosis of neoplasia in body fluids from dogs and cats","volume":"28","author":"Hirschberger","year":"1999"},{"key":"ref9","series-title":"J Vet Intern Med","first-page":"329","article-title":"Feline lymphoma in the post-feline leukemia virus era","volume":"19","author":"Louwerens","year":"2005"},{"key":"ref10","series-title":"Vet Clin Pathol","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1111\/j.1939-165X.1990.tb00548.x","article-title":"Lipoprotein electrophoresis differentiation of chylous and nonchylous pleural effusions in dogs and cats and its correlation with pleural effusion triglyceride concentration","volume":"19","author":"Waddle","year":"1990"},{"key":"ref11","series-title":"Int J Appl Res Vet Med","first-page":"159","article-title":"Corticosteroid-associated congestive heart failure in 12 cats","volume":"2","author":"Smith","year":"2004"},{"key":"ref12","series-title":"J Vet Intern Med","doi-asserted-by":"publisher","first-page":"1485","DOI":"10.1111\/jvim.12407","article-title":"Cardiac troponin I and T as prognostic markers in cats with hypertrophic cardiomyopathy","volume":"28","author":"Langhorn","year":"2014"},{"key":"ref13","series-title":"J Am Vet Med Assoc","doi-asserted-by":"publisher","first-page":"202","DOI":"10.2460\/javma.2002.220.202","article-title":"Population and survival characteristics of cats with hypertrophic cardiomyopathy: 260 cases (1990\u20131999)","volume":"220","author":"Rush","year":"2002"},{"key":"ref14","series-title":"J Small Anim Pract","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1111\/j.1748-5827.2011.01143.x","article-title":"Clinical signs and left atrial size in cats with cardiovascular disease in general practice","volume":"53","author":"Smith","year":"2012"},{"key":"ref15","series-title":"J Vet Intern Med","doi-asserted-by":"publisher","first-page":"1427","DOI":"10.1111\/jvim.12215","article-title":"Prognostic indicators in cats with hypertrophic cardiomyopathy","volume":"27","author":"Payne","year":"2013"},{"key":"ref16","series-title":"J Am Vet Med Assoc","first-page":"302","article-title":"Changes in clinical and laboratory findings in cats with hyperthyroidism from 1983 to 1993","volume":"206","author":"Broussard","year":"1995"},{"key":"ref17","series-title":"J Am Vet Med Assoc","first-page":"672","article-title":"Chylothorax in cats: 37 cases (1969\u20131989)","volume":"198","author":"Fossum","year":"1991"},{"key":"ref18","series-title":"J Feline Med Surg","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1016\/j.jfms.2004.12.004","article-title":"Feline pyothorax: a retrospective study of 27 cases in Australia","volume":"7","author":"Barrs","year":"2005"},{"key":"ref19","series-title":"Eur J Heart Fail","doi-asserted-by":"publisher","first-page":"1382","DOI":"10.1093\/eurjhf\/hft113","article-title":"Association of low body temperature and poor outcomes in patients admitted with worsening heart failure: a substudy of the Efficacy of Vasopressin Antagonism in Heart Failure Outcome Study with Tolvaptan (EVEREST) trial","volume":"15","author":"Payvar","year":"2013"},{"key":"ref20","series-title":"J Vet Intern Med","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1111\/jvim.12249","article-title":"Arterial thromboembolism in 250 cats in general practice: 2004\u20132012","volume":"28","author":"Borgeat","year":"2014"},{"key":"ref21","series-title":"J Vet Intern Med","doi-asserted-by":"publisher","first-page":"1002","DOI":"10.1111\/j.1939-1676.2007.tb03056.x","article-title":"Pericardial effusion in cats: a retrospective study of clinical findings and outcome in 146 cats","volume":"21","author":"Hall","year":"2007"},{"key":"ref22","series-title":"J Am Anim Hosp Assoc","doi-asserted-by":"publisher","first-page":"5","DOI":"10.5326\/0440005","article-title":"Disease association and clinical assessment of feline pericardial effusion","volume":"44","author":"Davidson","year":"2008"},{"key":"ref23","series-title":"J Am Anim Hosp Assoc","first-page":"39","article-title":"Pericardial disease in the cat: a retrospective evaluation of 66 cases","volume":"26","author":"Rush","year":"1990"}],"container-title":["Journal of the American Veterinary Medical 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