{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T04:31:05Z","timestamp":1790742665031,"version":"4.1.0"},"reference-count":41,"publisher":"American Veterinary Medical Association (AVMA)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2018,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p><jats:bold>OBJECTIVE<\/jats:bold> To identify risk factors associated with surgical site infection (SSI) in dogs following tibial plateau leveling osteotomy (TPLO).<\/jats:p>\n<jats:p><jats:bold>DESIGN<\/jats:bold> Retrospective cohort study.<\/jats:p>\n<jats:p><jats:bold>ANIMALS<\/jats:bold> 320 dogs that underwent unilateral or bilateral TPLO (n = 405 procedures) between 2007 and 2015 and were reexamined by a veterinarian at least once \u2265 8 weeks after the procedure.<\/jats:p>\n<jats:p><jats:bold>PROCEDURES<\/jats:bold> Data were extracted from medical records regarding signalment, TPLO procedure details, medical history of dermatitis, and SSI status. Logistic regression was performed to identify factors associated with SSI development.<\/jats:p>\n<jats:p><jats:bold>RESULTS<\/jats:bold> An SSI developed following 34 (8.4%; 95% confidence interval [CI], 6.1% to 11.5%) procedures. Prophylactic antimicrobial administration was provided following 36.8% (n = 149) of procedures. For 71 (17.5%) procedures, the dog had dermatitis at the time of surgery; 12 of these procedures involved dermatitis at the surgical site. The incidence of SSI following the 12 procedures for dogs with dermatitis at the surgical site was 16.7% (2\/12 [95% CI, 3.3% to 54.3%]) and was 10.2% (6\/59 [95% CI, 4.5% to 21.3%]) for dogs with dermatitis elsewhere; however, these differences in incidence were not significant. On multivariable analysis, German Shepherd Dogs (vs other breeds), meniscectomy (vs no meniscectomy), and attending surgeon having performed \u2264 20 (vs &gt; 20) procedures during the study period were associated with increased odds of SSI.<\/jats:p>\n<jats:p><jats:bold>CONCLUSIONS AND CLINICAL RELEVANCE<\/jats:bold> SSI following TPLO was associated with the German Shepherd breed, meniscectomy, and surgeon. Prospective studies are needed to investigate the mechanisms underlying these associations.<\/jats:p>","DOI":"10.2460\/javma.253.3.315","type":"journal-article","created":{"date-parts":[[2018,7,18]],"date-time":"2018-07-18T12:55:22Z","timestamp":1531918522000},"page":"315-321","source":"Crossref","is-referenced-by-count":35,"title":["Retrospective study of factors associated with surgical site infection in dogs following tibial plateau leveling osteotomy"],"prefix":"10.2460","volume":"253","author":[{"given":"Daniel J.","family":"Lopez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gretchen M.","family":"VanDeventer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ursula","family":"Krotscheck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yazdan","family":"Aryazand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina J.","family":"McConkey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kei","family":"Hayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rory J.","family":"Todhunter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Galina M.","family":"Hayes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"Vet Clin North Am Small Anim Pract","doi-asserted-by":"publisher","first-page":"777","DOI":"10.1016\/S0195-5616(93)50082-7","article-title":"Tibial plateau leveling osteotomy for repair of cranial cruciate ligament rupture in the canine","volume":"23","author":"Slocum","year":"1993"},{"key":"ref2","series-title":"Vet Surg","first-page":"2","article-title":"Prospective surgical site infection surveillance in dogs","volume":"44","author":"Turk","year":"2015"},{"key":"ref3","series-title":"Vet Surg","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1111\/j.1532-950X.2010.00663.x","article-title":"Predictive variables for complications after TPLO with stifle inspection by arthrotomy in 1000 consecutive dogs","volume":"39","author":"Fitzpatrick","year":"2010"},{"key":"ref4","series-title":"Vet Comp Orthop Traumatol","doi-asserted-by":"publisher","first-page":"333","DOI":"10.3415\/VCOT-10-07-0109","article-title":"Retrospective study of 476 tibial plateau levelling osteotomy procedures. 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