{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T04:20:28Z","timestamp":1768623628256,"version":"3.49.0"},"reference-count":55,"publisher":"American Veterinary Medical Association (AVMA)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2019,10,15]]},"abstract":"Abstract<\/jats:title>\n\nOBJECTIVE<\/jats:title>\nTo determine complication rates for dogs in which full-thickness large intestinal incisions were performed, assess potential risk factors for death during hospitalization and for intestinal dehiscence following these surgeries, and report short-term mortality rates for these patients.<\/jats:p>\n<\/jats:sec>\n\nANIMALS<\/jats:title>\n90 dogs.<\/jats:p>\n<\/jats:sec>\n\nPROCEDURES<\/jats:title>\nMedical records of 4 veterinary referral hospitals were reviewed to identify dogs that underwent large intestinal surgery requiring full-thickness incisions. Signalment, history, clinicopathologic data, medical treatments, surgical procedures, complications, and outcomes were recorded. Descriptive statistics were calculated; data were analyzed for association with survival to discharge (with logistic regression analysis) and postoperative intestinal dehiscence (with Fisher exact or Wilcoxon rank sum tests).<\/jats:p>\n<\/jats:sec>\n\nRESULTS<\/jats:title>\nOverall 7-day postoperative intestinal dehiscence and mortality rates were 9 of 90 (10%) and 15 of 90 (17%). Dogs with preoperative anorexia, hypoglycemia, or neutrophils with toxic changes and those that received preoperative antimicrobial treatment had greater odds of death than did dogs without these findings. Preexisting colon trauma or dehiscence, preexisting peritonitis, administration of blood products, administration of > 2 classes of antimicrobials, positive microbial culture results for a surgical sample, and open abdominal management of peritonitis after surgery were associated with development of intestinal dehiscence. Five of 9 dogs with intestinal dehiscence died or were euthanized.<\/jats:p>\n<\/jats:sec>\n\nCONCLUSIONS AND CLINICAL RELEVANCE<\/jats:title>\nFactors associated with failure to survive to discharge were considered suggestive of sepsis. Results suggested the dehiscence rate for full-thickness large intestinal incisions may not be as high as previously reported, but several factors may influence this outcome and larger, longer-term studies are needed to confirm these findings.<\/jats:p>\n<\/jats:sec>","DOI":"10.2460\/javma.255.8.915","type":"journal-article","created":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T19:16:43Z","timestamp":1569957403000},"page":"915-925","source":"Crossref","is-referenced-by-count":13,"title":["Evaluation of short-term outcomes and potential risk factors for death and intestinal dehiscence following full-thickness large intestinal incisions in dogs"],"prefix":"10.2460","volume":"255","author":[{"given":"Christian R.","family":"Latimer","sequence":"first","affiliation":[{"name":"1Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN 37996."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cassie N.","family":"Lux","sequence":"additional","affiliation":[{"name":"1Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN 37996."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janet A.","family":"Grimes","sequence":"additional","affiliation":[{"name":"2Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA 30602."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marian E.","family":"Benitez","sequence":"additional","affiliation":[{"name":"3Department of Small Animal Clinical Sciences, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William T. N.","family":"Culp","sequence":"additional","affiliation":[{"name":"4Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California-Davis, Davis, CA 95616."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Ben-Aderet","sequence":"additional","affiliation":[{"name":"4Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California-Davis, Davis, CA 95616."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dorothy C.","family":"Brown","sequence":"additional","affiliation":[{"name":"5Martingale Consulting LLC, Media, PA 19063."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"Vet Surg","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1111\/vsu.12428","article-title":"Frequency of dehiscence in hand-sutured and stapled intestinal anastomoses in 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