{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:54:49Z","timestamp":1787025289235,"version":"build-2736575974"},"reference-count":15,"publisher":"American Veterinary Medical Association (AVMA)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2020,1,15]]},"abstract":"Abstract<\/jats:title>\n \n CASE DESCRIPTION<\/jats:title>\n A 1.5-year-old 4.0-kg (8.8-lb) castrated male mixed-breed cat was evaluated because of an 8-month history of repeated bleeding from a hole in the skin next to the left metatarsal pad.<\/jats:p>\n <\/jats:sec>\n \n CLINICAL FINDINGS<\/jats:title>\n The cat had swelling in the distal region of the left pelvic limb, and blood dripped from a 2-mm-diameter hole in the skin adjacent and proximal to the metatarsal pad. Radiographic findings for the distal aspect of the left pelvic limb were compatible with a soft tissue inflammatory process. Results of histologic examination of a wedge biopsy sample, including the affected skin and subcutaneous tissue, indicated cutaneous angiomatosis. Angiography revealed anomalous vessels in the metatarsal region.<\/jats:p>\n <\/jats:sec>\n \n TREATMENT AND OUTCOME<\/jats:title>\n Surgical resection of the skin, subcutaneous tissue, and anomalous vessels in the affected metatarsal region of the left pelvic limb was performed. However, similar abnormal clinical signs recurred and did not respond to treatment, including prednisolone (2.0 mg\/kg [0.9 mg\/lb], PO, q 12 h for 4 days) and doxycycline (10 mg\/kg [4.5 mg\/lb], PO, q 24 h). The left pelvic limb was amputated, and no recurrence of similar abnormalities in the cat's other limbs was evident within a 15-month follow-up period.<\/jats:p>\n <\/jats:sec>\n \n CLINICAL RELEVANCE<\/jats:title>\n Findings in the cat of the present report highlighted that cutaneous angiomatosis could recur in a short period of time and that amputation of the affected limb was a viable treatment option when surgical resection was not successful.<\/jats:p>\n <\/jats:sec>","DOI":"10.2460\/javma.256.2.226","type":"journal-article","created":{"date-parts":[[2020,1,7]],"date-time":"2020-01-07T14:17:52Z","timestamp":1578406672000},"page":"226-229","source":"Crossref","is-referenced-by-count":9,"title":["Progressive cutaneous angiomatosis in the metatarsal region of a cat"],"prefix":"10.2460","volume":"256","author":[{"given":"Camila Paula","family":"Baron","sequence":"first","affiliation":[{"name":"1Department of Veterinary Sciences, Veterinary Hospital, Federal University of Paran\u00e1, Palotina, 85950-000, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabiana Carla","family":"Puntel","sequence":"additional","affiliation":[{"name":"1Department of Veterinary Sciences, Veterinary Hospital, Federal University of Paran\u00e1, Palotina, 85950-000, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fab\u00edola Bono","family":"Fukushima","sequence":"additional","affiliation":[{"name":"1Department of Veterinary Sciences, Veterinary Hospital, Federal University of Paran\u00e1, Palotina, 85950-000, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olicies","family":"da Cunha","sequence":"additional","affiliation":[{"name":"1Department of Veterinary Sciences, Veterinary Hospital, Federal University of Paran\u00e1, Palotina, 85950-000, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"J Am Vet Med Assoc","doi-asserted-by":"publisher","first-page":"381","DOI":"10.2460\/javma.234.3.381","article-title":"Invasive cutaneous angiomatosis and thrombocytopenia in a cat","volume":"234","author":"Bulman-Fleming","year":"2009"},{"key":"ref2","series-title":"Vet Pathol","doi-asserted-by":"publisher","first-page":"378","DOI":"10.1354\/vp.42-3-378","article-title":"Cutaneous angiomatosis in a young dog","volume":"42","author":"Kim","year":"2005"},{"key":"ref3","series-title":"J Vet Diagn Invest","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1177\/1040638714548681","article-title":"Vascular hamartoma in the central nervous system of a foal","volume":"26","author":"Borel","year":"2014"},{"key":"ref4","series-title":"J Pediatr Hematol Oncol","doi-asserted-by":"publisher","first-page":"e236","DOI":"10.1097\/MPH.0000000000000800","article-title":"Delayed appearance of cutaneous lesions of cutaneovisceral angiomatosis (CAT) leading to misdiagnosis of immune thrombocytopenia","volume":"39","author":"Com","year":"2017"},{"key":"ref5","series-title":"J Cutan Pathol","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1111\/j.1600-0560.1994.tb00710.x","article-title":"Arteriovenous hemangioma: a clinicopathological and immunohistochemical study","volume":"21","author":"Koutlas","year":"1994"},{"key":"ref6","series-title":"Can Vet J","first-page":"547","article-title":"Cecal vascular hamartoma causing recurrent colic in an Arabian mare","volume":"55","author":"Nolf","year":"2014"},{"key":"ref7","series-title":"J Vet Cardiol","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1016\/j.jvc.2015.07.004","article-title":"Vascular hamartoma in the right ventricle of a dog: diagnosis and treatment","volume":"17","author":"Tjostheim","year":"2015"},{"key":"ref8","series-title":"Vet Pathol","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1354\/vp.39-2-286","article-title":"Angiolipomatous tumors in dogs and a cat","volume":"39","author":"Liggett","year":"2002"},{"key":"ref9","series-title":"J Feline Med Surg","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1016\/j.jfms.2010.12.006","article-title":"Cerebral vascular hamartoma in a geriatric cat","volume":"13","author":"Martin-Vaquero","year":"2011"},{"key":"ref10","series-title":"J Am Acad Dermatol","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1016\/S0190-9622(97)70169-5","article-title":"Cutaneous vascular anomalies. 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Hamartomas, malformations, and dilatation of preexisting vessels","volume":"37","author":"Requena","year":"1997"},{"key":"ref11","series-title":"Vet Pathol","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1354\/vp.38-1-108","article-title":"Cerebral vascular hamartomas in five dogs","volume":"38","author":"Smith","year":"2001"},{"key":"ref12","series-title":"J Am Vet Med Assoc","doi-asserted-by":"publisher","first-page":"1094","DOI":"10.2460\/javma.2001.219.1094","article-title":"Use of laser photocoagulation for treatment of cutaneous angiomatosis in one dog and two cats","volume":"219","author":"Peavy","year":"2001"},{"key":"ref13","series-title":"BMC Vet Res","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1186\/s12917-016-0637-4","article-title":"Nasal tissue-derived hamartoma in the maxillary gingiva of a calf","volume":"12","author":"Tsuka","year":"2016"},{"key":"ref14","series-title":"Skin diseases of the dog and cat: clinical and histopathologic diagnosis","first-page":"735","article-title":"Vascular tumors","author":"Gross","year":"2005"},{"key":"ref15","series-title":"Vet Dermatol","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1111\/j.1365-3164.2010.00883.x","article-title":"Cutaneous progressive angiomatosis on the muzzle of a dog, treated by laser photocoagulation therapy","volume":"21","author":"Olivieri","year":"2010"}],"container-title":["Journal of the American Veterinary Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/256\/2\/javma.256.2.226.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/256\/2\/javma.256.2.226.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/256\/2\/javma.256.2.226.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T20:54:34Z","timestamp":1696539274000},"score":1,"resource":{"primary":{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/256\/2\/javma.256.2.226.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,15]]},"references-count":15,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.2460\/javma.256.2.226","relation":{},"ISSN":["0003-1488"],"issn-type":[{"value":"0003-1488","type":"print"}],"subject":[],"published":{"date-parts":[[2020,1,15]]}}}