{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T15:24:20Z","timestamp":1761578660198},"reference-count":36,"publisher":"American Veterinary Medical Association (AVMA)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2020,8,15]]},"abstract":"Abstract<\/jats:title>\n\nCASE DESCRIPTION<\/jats:title>\n3 dogs were examined because of a sudden onset of signs of pain (1 dog) or paraparesis (2 dogs).<\/jats:p>\n<\/jats:sec>\n\nCLINICAL FINDINGS<\/jats:title>\nNeurologic findings consisted of myelopathy affecting the lumbar intumescence (1 dog) and T3-L3 myelopathy (2 dogs). In all dogs, MRI revealed spinal cord compression caused by L3-4 disk herniation. All dogs underwent routine surgical decompression of the intervertebral disk herniation. During MRI and decompressive surgery, physiologic variables were monitored. Immediately after surgery, all dogs were paraplegic with pelvic limb neurologic dysfunction consistent with myelopathy affecting the L4 through caudal spinal cord segments.<\/jats:p>\n<\/jats:sec>\n\nTREATMENT AND OUTCOME<\/jats:title>\nWithin 24 hours after surgery, repeated MRI in all dogs revealed hyperintensity in the spinal cord gray matter of the lumbar intumescence on T2-weighted images. In the absence of neurologic improvement, dogs were euthanized at 3, 91, and 34 days after surgery. Postmortem microscopic examination of each dog's spinal cord at the lumbar intumescence revealed necrosis of the gray matter with relative white matter preservation suggestive of an ischemic injury.<\/jats:p>\n<\/jats:sec>\n\nCLINICAL RELEVANCE<\/jats:title>\nDramatic neurologic deterioration following decompressive surgery for intervertebral disk herniation in dogs may be associated with the development of poliomyelomalacia secondary to ischemia. In these 3 dogs, ischemia developed despite probable maintenance of normal spinal cord blood flow and perfusion during anesthesia. To exclude other causes, such as compression or hemorrhage, MRI was repeated and revealed hyperintensity of the spinal cord gray matter on T2-weighted images, which microscopically corresponded with ischemic neurons and neuronal loss.<\/jats:p>\n<\/jats:sec>","DOI":"10.2460\/javma.257.4.397","type":"journal-article","created":{"date-parts":[[2020,7,27]],"date-time":"2020-07-27T12:27:39Z","timestamp":1595852859000},"page":"397-405","source":"Crossref","is-referenced-by-count":2,"title":["Poliomyelomalacia in three dogs that underwent hemilaminectomy for intervertebral disk herniation"],"prefix":"10.2460","volume":"257","author":[{"given":"Marc","family":"Kent","sequence":"first","affiliation":[{"name":"1Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA 30602."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renee M.","family":"Barber","sequence":"additional","affiliation":[{"name":"1Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA 30602."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric N.","family":"Glass","sequence":"additional","affiliation":[{"name":"3Section of Neurology and Neurosurgery, Red Bank Veterinary Hospital, Compassion First Pet Hospitals, Tinton Falls, NJ 07724."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan A.","family":"Arnold","sequence":"additional","affiliation":[{"name":"1Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA 30602."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherine F.","family":"Bibi","sequence":"additional","affiliation":[{"name":"1Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA 30602."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georgina V.","family":"Stewart","sequence":"additional","affiliation":[{"name":"1Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA 30602."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer L.","family":"Ruby","sequence":"additional","affiliation":[{"name":"2Department of Veterinary Biosciences and Diagnostic Imaging, College of Veterinary Medicine, University of Georgia, Athens, GA 30602."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Perlini","sequence":"additional","affiliation":[{"name":"2Department of Veterinary Biosciences and Diagnostic Imaging, College of Veterinary Medicine, University of Georgia, Athens, GA 30602."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon R.","family":"Platt","sequence":"additional","affiliation":[{"name":"1Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, 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