{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T20:58:06Z","timestamp":1791406686497,"version":"4.3.3"},"reference-count":23,"publisher":"American Veterinary Medical Association (AVMA)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2021,7,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:sec id=\"s001\">\n<jats:title>CASE DESCRIPTION<\/jats:title>\n<jats:p>A 16-year old castrated male domestic shorthair cat was evaluated at a veterinary teaching hospital because of polyuria, polydipsia, and weight loss of 2 months\u2019 duration.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"s002\">\n<jats:title>CLINICAL FINDINGS<\/jats:title>\n<jats:p>Hematologic and biochemical examination results were within respective reference ranges except for moderately high pancreas-specific lipase concentration. Ultrasonographic and cytologic evaluation revealed a hepatic mass with findings consistent with mild cholestasis and inflammation and a pancreatic mass that was initially identified as a neuroendocrine tumor.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"s003\">\n<jats:title>TREATMENT AND OUTCOME<\/jats:title>\n<jats:p>The cat underwent additional CT assessment and stereotactic body radiation therapy (SBRT; 3 fractions of 8 Gy, administered every other day) for treatment of the pancreatic tumor. Follow-up ultrasonographic and CT examinations indicated a partial response to SBRT, with a maximum CT-measured size reduction from 3.6 \u00d7 4.8 \u00d7 4.0 cm at the time of treatment planning to 2.0 \u00d7 2.0 \u00d7 1.9 cm 8 months later. Increased pancreatic tumor size and signs of carcinomatosis were detected 15 months after SBRT treatment; the initial cytologic diagnosis was changed to exocrine pancreatic carcinoma on reevaluation of the slides by another veterinary pathologist. Carboplatin treatment was elected, and signs of carcinomatosis resolved. The cat was euthanized without further testing because of weakness 589 days after SBRT was started.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"s004\">\n<jats:title>CLINICAL RELEVANCE<\/jats:title>\n<jats:p>To the authors\u2019 knowledge, this is the first report of SBRT for suspected exocrine pancreatic carcinoma in a cat. Further investigation is needed to determine optimal fractionation schedules for SBRT of pancreatic tumors and utility of SBRT of exocrine pancreatic carcinoma in cats. (<jats:italic>J Am Vet Med Assoc<\/jats:italic> 2021;259:184\u2013189)<\/jats:p>\n<\/jats:sec>","DOI":"10.2460\/javma.259.2.184","type":"journal-article","created":{"date-parts":[[2021,7,6]],"date-time":"2021-07-06T14:46:05Z","timestamp":1625582765000},"page":"184-189","source":"Crossref","is-referenced-by-count":2,"title":["Use of stereotactic body radiation therapy for treatment of a pancreatic tumor in a cat"],"prefix":"10.2460","volume":"259","author":[{"given":"Alba L.","family":"Gaitan-Cobo","sequence":"first","affiliation":[{"name":"From the College of Veterinary Medicine and Biological Sciences, Colorado State University, Ft Collins, CO 80523 (Gaitan-Cobo) and Department of Radiological Health Sciences (Griffin, Kruckman-Gatesy), College of Veterinary Medicine and Biological Sciences, Colorado State University, Ft Collins, CO 80523. Alba Gaitan-Cobo was a fourth-year veterinary student at the time the report was submitted."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynn R.","family":"Griffin","sequence":"additional","affiliation":[{"name":"From the College of Veterinary Medicine and Biological Sciences, Colorado State University, Ft Collins, CO 80523 (Gaitan-Cobo) and Department of Radiological Health Sciences (Griffin, Kruckman-Gatesy), College of Veterinary Medicine and Biological Sciences, Colorado State University, Ft Collins, CO 80523. Alba Gaitan-Cobo was a fourth-year veterinary student at the time the report was submitted."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolynne R.","family":"Kruckman-Gatesy","sequence":"additional","affiliation":[{"name":"From the College of Veterinary Medicine and Biological Sciences, Colorado State University, Ft Collins, CO 80523 (Gaitan-Cobo) and Department of Radiological Health Sciences (Griffin, Kruckman-Gatesy), College of Veterinary Medicine and Biological Sciences, Colorado State University, Ft Collins, CO 80523. 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