{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T14:39:09Z","timestamp":1790087949102,"version":"4.0.1"},"reference-count":41,"publisher":"Japanese Society for Magnetic Resonance in Medicine","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["MRMS","magn reson med sci"],"published-print":{"date-parts":[[2025]]},"DOI":"10.2463\/mrms.rev.2025-0004","type":"journal-article","created":{"date-parts":[[2025,8,19]],"date-time":"2025-08-19T22:10:09Z","timestamp":1755641409000},"page":"387-402","source":"Crossref","is-referenced-by-count":4,"title":["Endometrial Cancer: A Daily Clinical Practice Guide for Radiologists"],"prefix":"10.2463","volume":"24","author":[{"given":"Pamela","family":"Causa Andrieu","sequence":"first","affiliation":[{"name":"Department of Radiology, Mayo Clinic, Rochester, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giacomo","family":"Avesani","sequence":"additional","affiliation":[{"name":"Department of Imaging and Radiation Oncology, Policlinico Universitario Fondazione Agostino Gemelli, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stanislas","family":"Quesada","sequence":"additional","affiliation":[{"name":"D\u00e9partement d\u2019Oncologie M\u00e9dicale, L\u2019Institut du Cancer de Montpellier, Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel L.","family":"McPhedran","sequence":"additional","affiliation":[{"name":"Resident in the Department of Radiology, Mayo Clinic School of Graduate Medical Education, Mayo Clinic College of Medicine and Science, Rochester, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Rigiroli","sequence":"additional","affiliation":[{"name":"Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"Aineseder","sequence":"additional","affiliation":[{"name":"Service of Radiology, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Chacon","sequence":"additional","affiliation":[{"name":"Service of Radiology, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aki","family":"Kido","sequence":"additional","affiliation":[{"name":"Department of Imaging and Radiation Oncology, Policlinico Universitario Fondazione Agostino Gemelli, Rome, Italy"},{"name":"Department of Radiology, Toyama University Hospital, Toyama, Toyama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Nougaret","sequence":"additional","affiliation":[{"name":"Department of Radiology, L\u2019Institut du Cancer de Montpellier, Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1295","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Ferlay J, Colombet M, Soerjomataram I, et al. Cancer incidence and mortality patterns in Europe: Estimates for 40 countries and 25 major cancers in 2018. Eur J Cancer 2018; 103:356\u2013387.","DOI":"10.1016\/j.ejca.2018.07.005"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Sala E, Rockall AG, Freeman SJ, Mitchell DG, Reinhold C. The added role of MR imaging in treatment stratification of patients with gynecologic malignancies: What the radiologist needs to know. Radiology 2013; 266:717\u2013740.","DOI":"10.1148\/radiol.12120315"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Abu-Rustum N, Yashar C, Arend R, et al. Uterine neoplasms, version 1.2023, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw 2023; 21:181\u2013209.","DOI":"10.6004\/jnccn.2023.0006"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Kandoth C, Schultz N, Cherniack AD, et al. Integrated genomic characterization of endometrial carcinoma. Nature 2013; 497:67\u201373.","DOI":"10.1038\/nature12113"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. de Boer SM, Powell ME, Mileshkin L, et al. Adjuvant chemoradiotherapy versus radiotherapy alone in women with high-risk endometrial cancer (PORTEC-3): Patterns of recurrence and post-hoc survival analysis of a randomised phase 3 trial. Lancet Oncol 2019; 20:1273\u20131285.","DOI":"10.1016\/S1470-2045(19)30395-X"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Berek JS, Matias\u2010Guiu X, Creutzberg C, et al. FIGO staging of endometrial cancer: 2023. Int J Gynaecol Obstet 2023; 162:383\u2013394.","DOI":"10.1002\/ijgo.14923"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Post CCB, De Boer SM, Powell ME, et al. Long-term toxicity and health-related quality of life after adjuvant chemoradiation therapy or radiation therapy alone for high-risk endometrial cancer in the randomized PORTEC-3 trial. Int J Radiat Oncol Biol Phys 2021; 109:975\u2013986.","DOI":"10.1016\/j.ijrobp.2020.10.030"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Avesani G, Bonatti M, Venkatesan AM, Nougaret S, Sala E. RadioGraphics update: 2023 FIGO staging system for endometrial cancer. Radiographics 2024; 44:e240084.","DOI":"10.1148\/rg.240084"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Kido A, Himoto Y, Kurata Y, Minamiguchi S, Nakamoto Y. Preoperative imaging evaluation of endometrial cancer in FIGO 2023. J Magn Reson Imaging 2024; 60:1225\u20131242.","DOI":"10.1002\/jmri.29161"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Nougaret S, Horta M, Sala E, et al. Endometrial cancer MRI staging: Updated guidelines of the European Society of Urogenital Radiology. Eur Radiol 2019; 29:792\u2013805.","DOI":"10.1007\/s00330-018-5515-y"},{"key":"11","unstructured":"11. Japan Radiological Society. Diagnostic Imaging Guidelines. Tokyo:Kanehara &amp; Co. Ltd, 2021. https:\/\/www.radiology.jp\/content\/files\/gl2021\/diagnostic_imaging_guidelines_2021e.pdf"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Lee MS, Moon MH, Kim TM, Jang S, Oh S, Cho JY. Contrast-enhanced MRI in women with endometrial cancer: Dynamic versus single-phase acquisitions. Clin Med Insights Oncol 2023; 17:11795549231207833.","DOI":"10.1177\/11795549231207833"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Nougaret S, Lakhman Y, Vargas HA, et al. From staging to prognostication: Achievements and challenges of MR imaging in the assessment of endometrial cancer. Magn Reson Imaging Clin N Am 2017; 25:611\u2013633.","DOI":"10.1016\/j.mric.2017.03.010"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Maheshwari E, Nougaret S, Stein EB, et al. Update on MRI in evaluation and treatment of endometrial cancer. Radiographics 2022; 42:2112\u20132130.","DOI":"10.1148\/rg.220070"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. ACOG Committee Opinion No. 734: The role of transvaginal ultrasonography in evaluating the endometrium of women with postmenopausal bleeding. Obstet Gynecol 2018; 131:e124\u2013e129.","DOI":"10.1097\/AOG.0000000000002631"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Beddy P, Moyle P, Kataoka M, et al. Evaluation of depth of myometrial invasion and overall staging in endometrial cancer: Comparison of diffusion-weighted and dynamic contrast-enhanced MR imaging. Radiology 2012; 262:530\u2013537.","DOI":"10.1148\/radiol.11110984"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Sala E, Rockall A, Kubik-Huch RA. Advances in magnetic resonance imaging of endometrial cancer. Eur Radiol 2011; 21:468\u2013473.","DOI":"10.1007\/s00330-010-2010-5"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Gui B, Lupinelli M, Russo L, et al. MRI in uterine cancers with uncertain origin: Endometrial or cervical? Radiological point of view with review of the literature. Eur J Radiol 2022; 153:110357.","DOI":"10.1016\/j.ejrad.2022.110357"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Andreano A, Rechichi G, Rebora P, Sironi S, Valsecchi MG, Galimberti S. MR diffusion imaging for preoperative staging of myometrial invasion in patients with endometrial cancer: A systematic review and meta-analysis. Eur Radiol 2014; 24:1327\u20131338.","DOI":"10.1007\/s00330-014-3139-4"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Mad\u00e1r I, Szab\u00f3 A, Vlesk\u00f3 G, et al. Diagnostic accuracy of transvaginal ultrasound and magnetic resonance imaging for the detection of myometrial infiltration in endometrial cancer: A systematic review and meta-analysis. Cancers (Basel) 2024; 16:907.","DOI":"10.3390\/cancers16050907"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Frei KA, Kinkel K, Bon\u00e9l HM, Lu Y, Zaloudek C, Hricak H. Prediction of deep myometrial invasion in patients with endometrial cancer: Clinical utility of contrast-enhanced MR imaging-a meta-analysis and bayesian analysis. Radiology 2000; 216:444\u2013449.","DOI":"10.1148\/radiology.216.2.r00au17444"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Bhosale P, Ma J, Iyer R, et al. Feasibility of a reduced field\u2010of\u2010view diffusion\u2010weighted (rFOV) sequence in assessment of myometrial invasion in patients with clinical FIGO stage I endometrial cancer. J Magn Reson Imaging 2016; 43:316\u2013324.","DOI":"10.1002\/jmri.25001"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Concin N, Matias-Guiu X, Vergote I, et al. ESGO\/ESTRO\/ESP guidelines for the management of patients with endometrial carcinoma. Radiother Oncol 2021; 154:327\u2013353.","DOI":"10.1016\/j.radonc.2020.11.018"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Turan T, H\u0131zl\u0131 D, Y\u0131lmaz SS, et al. What is the impact of cervical invasion on lymph node metastasis in patients with stage IIIC endometrial cancer? Arch Gynecol Obstet 2012; 285:1119\u20131124.","DOI":"10.1007\/s00404-011-2030-7"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Malek M, Rahmani M, Pourashraf M, et al. Prediction of lymphovascular space invasion in cervical carcinoma using diffusion kurtosis imaging. Cancer Treat Res Commun 2022; 31:100559.","DOI":"10.1016\/j.ctarc.2022.100559"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26. Himoto Y, Lakhman Y, Fujii S, et al. Multiparametric magnetic resonance imaging facilitates the selection of patients prior to fertility-sparing management of endometrial cancer. Abdom Radiol (NY) 2021; 46:4410\u20134419.","DOI":"10.1007\/s00261-021-03050-7"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27. Saida T, Sakata A, Tanaka YO, et al. Clinical and MRI characteristics of uterine cervical adenocarcinoma: Its variants and mimics. Korean J Radiol 2019; 20:364\u2013377.","DOI":"10.3348\/kjr.2018.0458"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28. Anglesio MS, Wang YK, Maassen M, et al. Synchronous endometrial and ovarian carcinomas: Evidence of clonality. J Natl Cancer Inst 2016; 108:djv428.","DOI":"10.1093\/jnci\/djv428"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29. Schultheis AM, Ng CKY, De Filippo MR, et al. Massively parallel sequencing-based clonality analysis of synchronous endometrioid endometrial and ovarian carcinomas. J Natl Cancer Inst 2016; 108:djv427.","DOI":"10.1093\/jnci\/djv427"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30. Sadowski EA, Thomassin-Naggara I, Rockall A, et al. O-RADS MRI risk stratification system: Guide for assessing adnexal lesions from the ACR O-RADS Committee. Radiology 2022; 303:35\u201347.","DOI":"10.1148\/radiol.204371"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31. Vargas HA, Akin O, Zheng J, et al. The value of MR imaging when the site of uterine cancer origin is uncertain. Radiology 2011; 258:785\u2013792.","DOI":"10.1148\/radiol.10101147"},{"key":"32","doi-asserted-by":"crossref","unstructured":"32. Shen G, Zhou H, Jia Z, Deng H. Diagnostic performance of diffusion-weighted MRI for detection of pelvic metastatic lymph nodes in patients with cervical cancer: A systematic review and meta-analysis. Br J Radiol 2015; 88:20150063.","DOI":"10.1259\/bjr.20150063"},{"key":"33","doi-asserted-by":"crossref","unstructured":"33. Micc\u00f2 M, Sala E, Lakhman Y, Hricak H, Vargas HA. Role of imaging in the pretreatment evaluation of common gynecological cancers. Womens Health (Lond Engl) 2014; 10:299\u2013321.","DOI":"10.2217\/WHE.14.19"},{"key":"34","doi-asserted-by":"crossref","unstructured":"34. Liu Y, Chi S, Zhou X, Zhao R, Xiao C, Wang H. Prognostic value of distant metastatic sites in stage IV endometrial cancer: A SEER database study of 2948 women. Int J Gynaecol Obstet 2020; 149:16\u201323.","DOI":"10.1002\/ijgo.13084"},{"key":"35","doi-asserted-by":"crossref","unstructured":"35. Mapelli P, Ironi G, Bergamini A, et al. Synergic role of preoperative 18Ffluorodeoxyglucose PET and MRI parameters in predicting histopathological features of endometrial cancer. Nucl Med Commun 2020; 41:1073\u20131080.","DOI":"10.1097\/MNM.0000000000001257"},{"key":"36","doi-asserted-by":"crossref","unstructured":"36. Ironi G, Mapelli P, Bergamini A, et al. Hybrid PET\/MRI in staging endometrial cancer: Diagnostic and predictive value in a prospective cohort. Clin Nucl Med 2022; 47:e221\u2013e229.","DOI":"10.1097\/RLU.0000000000004064"},{"key":"37","doi-asserted-by":"crossref","unstructured":"37. Bian L, Wang M, Gong J, et al. Comparison of integrated PET\/MRI with PET\/CT in evaluation of endometrial cancer: A retrospective analysis of 81 cases. PeerJ 2019; 7:e7081.","DOI":"10.7717\/peerj.7081"},{"key":"38","doi-asserted-by":"crossref","unstructured":"38. Kesner AL. The evolution of PET\/MR is hindered by our field\u2019s reluctance to provide critical evaluation. J Nucl Med 2021; 62:462\u2013463.","DOI":"10.2967\/jnumed.120.260950"},{"key":"39","doi-asserted-by":"crossref","unstructured":"39. Nguyen NC, Beriwal S, Moon C-H, et al. Diagnostic value of FDG PET\/MRI in females with pelvic malignancy\u2014A systematic review of the literature. Front Oncol 2020; 10:519440.","DOI":"10.3389\/fonc.2020.519440"},{"key":"40","doi-asserted-by":"crossref","unstructured":"40. Bollineni VR, Ytre-Hauge S, Bollineni-Balabay O, Salvesen HB, Haldorsen IS. High diagnostic value of 18F-FDG PET\/CT in endometrial cancer: Systematic review and meta-analysis of the literature. J Nucl Med 2016; 57:879\u2013885.","DOI":"10.2967\/jnumed.115.170597"},{"key":"41","doi-asserted-by":"crossref","unstructured":"41. Nougaret S, Sala E, Lakhman Y, et al. Updated ESUR guidelines for endometrial cancer: Integrating MRI with the 2023 FIGO Staging Revolution. Eur Radiol 2025. [Epub ahead of print].","DOI":"10.1007\/s00330-025-11700-3"}],"container-title":["Magnetic Resonance in Medical Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/mrms\/24\/3\/24_rev.2025-0004\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,23]],"date-time":"2025-08-23T05:04:37Z","timestamp":1755925477000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/mrms\/24\/3\/24_rev.2025-0004\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":41,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.2463\/mrms.rev.2025-0004","relation":{},"ISSN":["1347-3182","1880-2206"],"issn-type":[{"value":"1347-3182","type":"print"},{"value":"1880-2206","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]},"article-number":"rev.2025-0004"}}