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An experimental assessment of motor development in spatial cognition in a simulated virtual maze by school-age children is lacking. In this study children with Spina bifida, who were impaired in walking since birth, completed four visuospatial tasks in a small-scale space (Mental Rotation, Water-Level Task, Embedded Figures Test, Visual Short-term Memory Test), and a spatial behaviour and knowledge task in a virtual maze. These children showed poorer performance than children in the control group on most measures. 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