{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T04:16:14Z","timestamp":1783743374960,"version":"3.55.0"},"reference-count":44,"publisher":"WHO Press","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bull. World Health Organ."],"published-print":{"date-parts":[[2013,2,1]]},"DOI":"10.2471\/blt.12.108944","type":"journal-article","created":{"date-parts":[[2013,2,4]],"date-time":"2013-02-04T15:23:49Z","timestamp":1359991429000},"page":"93-101","source":"Crossref","is-referenced-by-count":29,"title":["Methadone maintenance treatment and mortality in HIV-positive people who inject opioids in China"],"prefix":"10.2471","volume":"91","author":[{"given":"Yan","family":"Zhao","sequence":"first","affiliation":[{"name":"National Center for AIDS\/STD Control and Prevention, Chinese Center for Disease Control and Prevention, 155 Changbai Road, Changping District, Beijing, 102206, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cynthia X","family":"Shi","sequence":"additional","affiliation":[{"name":"National Center for AIDS\/STD Control and Prevention, Chinese Center for Disease Control and Prevention, 155 Changbai Road, Changping District, Beijing, 102206, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer M","family":"McGoogan","sequence":"additional","affiliation":[{"name":"National Center for AIDS\/STD Control and Prevention, Chinese Center for Disease Control and Prevention, 155 Changbai Road, Changping District, Beijing, 102206, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keming","family":"Rou","sequence":"additional","affiliation":[{"name":"National Center for AIDS\/STD Control and Prevention, Chinese Center for Disease Control and Prevention, 155 Changbai Road, Changping District, Beijing, 102206, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fujie","family":"Zhang","sequence":"additional","affiliation":[{"name":"National Center for AIDS\/STD Control and Prevention, Chinese Center for Disease Control and Prevention, 155 Changbai Road, Changping District, Beijing, 102206, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zunyou","family":"Wu","sequence":"additional","affiliation":[{"name":"National Center for AIDS\/STD Control and Prevention, Chinese Center for Disease Control and Prevention, 155 Changbai Road, Changping District, Beijing, 102206, China."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1305","reference":[{"key":"key-10.2471\/BLT.12.108944-201302041119-R1","unstructured":"2012 China AIDS response progress report. Beijing: Ministry of Health; 2012."},{"key":"key-10.2471\/BLT.12.108944-201302041119-R2","doi-asserted-by":"publisher","first-page":"1733","DOI":"10.1016\/S0140-6736(08)61311-2","article-title":"Global epidemiology of injecting drug use and HIV among people who inject drugs: a systematic review.","volume":"372","author":"Mathers","year":"2008","journal-title":"Lancet"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R3","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1521\/aeap.16.3.5.7.35521","article-title":"The HIV\/AIDS epidemic in China: history, current strategies and future challenges.","volume":"16","author":"Wu","year":"2004","journal-title":"AIDS Educ Prev"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R4","unstructured":"National Narcotics Control Commission.Annual report on drug control in China 2011.Beijing: Ministry of Public Security; 2011."},{"key":"key-10.2471\/BLT.12.108944-201302041119-R5","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1016\/S0140-6736(07)60315-8","article-title":"Evolution of China\u2019s response to HIV\/AIDS.","volume":"369","author":"Wu","year":"2007","journal-title":"Lancet"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R6","doi-asserted-by":"publisher","first-page":"ii29","DOI":"10.1093\/ije\/dyq210","article-title":"Scaling up the national methadone maintenance treatment program in China: achievements and challenges.","volume":"39","author":"Yin","year":"2010","journal-title":"Int J Epidemiol"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R7","doi-asserted-by":"publisher","first-page":"ii47","DOI":"10.1093\/ije\/dyq212","article-title":"Design and implementation of a China comprehensive AIDS response programme (China CARES), 2003\u201308.","volume":"39","author":"Han","year":"2010","journal-title":"Int J Epidemiol"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R8","unstructured":"National Center for AIDS\/STD Control and Prevention, China CDC.National monthly report on statistics of epidemics and prevention and treatment of HIV\/AIDS, STD and hepatitis C in China (April 2012).Beijing: National Center for AIDS\/STD Control and Prevention, China CDC; 2012."},{"key":"key-10.2471\/BLT.12.108944-201302041119-R9","doi-asserted-by":"publisher","first-page":"825","DOI":"10.1086\/590945","article-title":"The effect of highly active antiretroviral therapy on mortality among HIV-infected former plasma donors in China.","volume":"47","author":"Zhang","year":"2008","journal-title":"Clin Infect Dis"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R10","doi-asserted-by":"crossref","first-page":"241","DOI":"10.7326\/0003-4819-151-4-200908180-00006","article-title":"Five-year outcomes of the China National Free Antiretroviral Treatment Program.","volume":"151","author":"Zhang","year":"2009","journal-title":"Ann Intern Med"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R11","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1086\/649215","article-title":"Predictors of virologic failure in HIV-1-infected adults receiving first-line antiretroviral therapy in 8 provinces in China.","volume":"50","author":"Ma","year":"2010","journal-title":"Clin Infect Dis"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R12","doi-asserted-by":"publisher","first-page":"516","DOI":"10.1016\/S1473-3099(11)70097-4","article-title":"Effect of earlier initiation of antiretroviral treatment and increased treatment coverage on HIV-related mortality in China: a national observational cohort study.","volume":"11","author":"Zhang","year":"2011","journal-title":"Lancet Infect Dis"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R13","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1007\/s11904-010-0059-z","article-title":"Drug treatment as HIV prevention: expanding treatment options.","volume":"7","author":"Metzger","year":"2010","journal-title":"Curr HIV\/AIDS Rep"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R14","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1016\/S0140-6736(10)60832-X","article-title":"Treatment and care for injecting drug users with HIV infection: a review of barriers and ways forward.","volume":"376","author":"Wolfe","year":"2010","journal-title":"Lancet"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R15","doi-asserted-by":"publisher","first-page":"ii56","DOI":"10.1093\/ije\/dyq215","article-title":"Changing baseline characteristics among patients in the China National Free Antiretroviral Treatment Program, 2002\u201309.","volume":"39","author":"Dou","year":"2010","journal-title":"Int J Epidemiol"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R16","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1097\/QAI.0b013e3181b31b8a","article-title":"Differential survival benefit of universal HAART access in Brazil: a nation-wide comparison of injecting drug users versus men who have sex with men.","volume":"52","author":"Malta","year":"2009","journal-title":"J Acquir Immune Defic Syndr"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R17","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1111\/j.1360-0443.2009.02827.x","article-title":"Impact of injecting drug use on mortality in Danish HIV-infected patients: a nation-wide population-based cohort study.","volume":"105","author":"Larsen","year":"2010","journal-title":"Addiction"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R18","doi-asserted-by":"publisher","first-page":"e4445","DOI":"10.1371\/journal.pone.0004445","article-title":"Late HIV diagnosis and determinants of progression to AIDS or death after HIV diagnosis among injection drug users, 33 US states, 1996\u20132004.","volume":"4","author":"Grigoryan","year":"2009","journal-title":"PLoS One"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R19","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1016\/j.drugpo.2007.05.002","article-title":"Antiretroviral HIV treatment and care for injecting drug users: an evidence-based overview.","volume":"18","author":"Lert","year":"2007","journal-title":"Int J Drug Policy"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R20","doi-asserted-by":"publisher","first-page":"1828","DOI":"10.1111\/j.1360-0443.2008.02323.x","article-title":"The impact of methadone or buprenorphine treatment and ongoing injection on highly active antiretroviral therapy (HAART) adherence: evidence from the MANIF2000 cohort study.","volume":"103","author":"Roux","year":"2008","journal-title":"Addiction"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R21","doi-asserted-by":"publisher","first-page":"1433","DOI":"10.1086\/630209","article-title":"Retention in opioid substitution treatment: a major predictor of long-term virological success for HIV-infected injection drug users receiving antiretroviral treatment.","volume":"49","author":"Roux","year":"2009","journal-title":"Clin Infect Dis"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R22","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1111\/j.1468-1293.2009.00701.x","article-title":"Uptake of and virological response to antiretroviral therapy among HIV-infected former and current injecting drug users and persons in an opiate substitution treatment programme: the Swiss HIV Cohort Study.","volume":"10","author":"Weber","year":"2009","journal-title":"HIV Med"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R23","doi-asserted-by":"publisher","first-page":"907","DOI":"10.1111\/j.1360-0443.2010.02905.x","article-title":"Methadone maintenance therapy promotes initiation of antiretroviral therapy among injection drug users.","volume":"105","author":"Uhlmann","year":"2010","journal-title":"Addiction"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R24","doi-asserted-by":"publisher","first-page":"S103","DOI":"10.1097\/01.aids.0000304704.71917.64","article-title":"Effectiveness of first eight methadone maintenance treatment clinics in China.","volume":"21","author":"Pang","year":"2007","journal-title":"AIDS"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R25","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1016\/j.addbeh.2011.11.004","article-title":"Concurrent heroin use among methadone maintenance clients in China.","volume":"37","author":"Li","year":"2012","journal-title":"Addict Behav"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R26","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1111\/j.1360-0443.2004.00963.x","article-title":"Decreasing international HIV transmission: the role of expanding access to opioid agonist therapies for injection drug users.","volume":"100","author":"Sullivan","year":"2005","journal-title":"Addiction"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R27","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1093\/ije\/dyq213","article-title":"Integration of methadone maintenance treatment and HIV care for injecting drug users: a cohort study in Bandung, Indonesia.","volume":"41","author":"Achmad","year":"2009","journal-title":"Acta Med Indones"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R28","unstructured":"World Health Organization.Antiretroviral therapy for HIV infection in adults and adolescents: recommendations for a public health approach.2010 revision. Geneva: World Health Organization; 2010."},{"key":"key-10.2471\/BLT.12.108944-201302041119-R29","unstructured":"Ministry of Health Working Group on Clinical AIDS Treatment.China free antiretroviral treatment manual.Beijing: People's Medical Publishing House; 2012."},{"key":"key-10.2471\/BLT.12.108944-201302041119-R30","unstructured":"Community maintenance treatment procedures for opiate addicts.Beijing; Ministry of Health, Ministry of Public Security, State Food and Drug Administration; 2006. [Chinese]."},{"key":"key-10.2471\/BLT.12.108944-201302041119-R31","doi-asserted-by":"publisher","first-page":"ii79","DOI":"10.1093\/ije\/dyq213","article-title":"Development of a unified web-based national HIV\/AIDS information system in China.","volume":"39","author":"Mao","year":"2010","journal-title":"Int J Epidemiol"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R32","doi-asserted-by":"publisher","first-page":"973","DOI":"10.1093\/ije\/dyp233","article-title":"Cohort profile: the Chinese national free antiretroviral treatment cohort.","volume":"39","author":"Ma","year":"2010","journal-title":"Int J Epidemiol"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R33","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1016\/j.drugpo.2006.12.014","article-title":"Adherence to HIV treatment among IDUs and the role of opioid substitution treatment (OST).","volume":"18","author":"Spire","year":"2007","journal-title":"Int J Drug Policy"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R34","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1111\/j.1468-1293.2008.00582.x","article-title":"Poor adherence to HIV monitoring and treatment guidelines for HIV-infected injection drug users.","volume":"9","author":"Wood","year":"2008","journal-title":"HIV Med"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R35","doi-asserted-by":"publisher","first-page":"1484","DOI":"10.1111\/j.1360-0443.2008.02249.x","article-title":"Key findings from the WHO collaborative study on substitution therapy for opioid dependence and HIV\/AIDS.","volume":"103","author":"Lawrinson","year":"2008","journal-title":"Addiction"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R36","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1016\/j.cct.2009.05.003","article-title":"Rationale, design, and sample characteristics of a randomized controlled trial of directly observed antiretroviral therapy delivered in methadone clinics.","volume":"30","author":"Berg","year":"2009","journal-title":"Contemp Clin Trials"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R37","doi-asserted-by":"publisher","first-page":"1628","DOI":"10.1086\/503905","article-title":"Directly administered antiretroviral therapy in methadone clinics is associated with improved HIV treatment outcomes, compared with outcomes among concurrent comparison groups.","volume":"42","author":"Lucas","year":"2006","journal-title":"Clin Infect Dis"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R38","doi-asserted-by":"publisher","first-page":"e28691","DOI":"10.1371\/journal.pone.0028691","article-title":"Early mortality in adults initiating antiretroviral therapy (ART) in low- and middle-income countries (LMIC): a systematic review and meta-analysis.","volume":"6","author":"Gupta","year":"2011","journal-title":"PLoS One"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R39","doi-asserted-by":"publisher","first-page":"1454","DOI":"10.1086\/383031","article-title":"Anemia in HIV infection: clinical impact and evidence-based management strategies.","volume":"38","author":"Volberding","year":"2004","journal-title":"Clin Infect Dis"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R40","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1097\/01.qai.0000166374.16222.a2","article-title":"Anemia is an independent predictor of mortality and immunologic progression of disease among women with HIV in Tanzania.","volume":"40","author":"O\u2019Brien","year":"2005","journal-title":"J Acquir Immune Defic Syndr"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R41","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1097\/QAI.0b013e31824bd33f","article-title":"Predictors of 5-year mortality in HIV-infected adults starting highly active antiretroviral therapy in Thailand.","volume":"60","author":"Fregonese","year":"2012","journal-title":"J Acquir Immune Defic Syndr"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R42","doi-asserted-by":"publisher","first-page":"544","DOI":"10.1001\/jama.280.6.544","article-title":"Self-reported antiretroviral therapy in injection drug users.","volume":"280","author":"Celentano","year":"1998","journal-title":"JAMA"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R43","doi-asserted-by":"publisher","first-page":"e1000423","DOI":"10.1371\/journal.pmed.1000423","article-title":"Effectiveness and cost effectiveness of expanding harm reduction and antiretroviral therapy in a mixed HIV epidemic: a modeling analysis for Ukraine.","volume":"8","author":"Alistar","year":"2011","journal-title":"PLoS Med"},{"key":"key-10.2471\/BLT.12.108944-201302041119-R44","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1080\/09540121.2011.608420","article-title":"Cost-effectiveness of methadone maintenance treatment for HIV-positive drug users in Vietnam.","volume":"24","author":"Tran","year":"2012","journal-title":"AIDS Care"}],"container-title":["Bulletin of the World Health Organization"],"original-title":[],"deposited":{"date-parts":[[2025,3,19]],"date-time":"2025-03-19T17:11:20Z","timestamp":1742404280000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3605005\/pdf\/BLT.12.108944.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2,1]]},"references-count":44,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,2,1]]}},"URL":"https:\/\/doi.org\/10.2471\/blt.12.108944","relation":{},"ISSN":["0042-9686"],"issn-type":[{"value":"0042-9686","type":"print"}],"subject":[],"published":{"date-parts":[[2013,2,1]]}}}