{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T15:28:38Z","timestamp":1789140518943,"version":"build-2803163510"},"reference-count":30,"publisher":"Walter de Gruyter GmbH","issue":"5","license":[{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Eosinophilia is a common, hematologic abnormality detected in periodic health checkups with diverse etiologies. There are a few clinical practice guidelines for the management of eosinophilia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To determine the prevalence of eosinophilia among patients undergoing periodic health examinations, evaluate its management and outcomes, and identify its associated factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective study that included patients with eosinophilia diagnosed during the 2018 periodic health examinations at Songklanagarind Hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The prevalence rate of eosinophilia was 9.6% (988\/10,299), and most patients (52.6%) were male with a median age of 53.0 (42.0\u201361.0) years. Only 174 patients (17.6%) were diagnosed and further examined to identify the cause of eosinophilia; including an examination of medical history (18.4%), physical examination (93.1%), laboratory analysis (9.2%), and consultation with internists (14.9%). Empirical anthelmintic therapy was administered in 130 patients (74.7%), and 49.2% achieved resolution. The possible causes of eosinophilia were identified in 20.7% (204\/988), the most common cause being atopic disease (51.5%). Patients with moderate-to-severe eosinophilia were significantly more likely to be diagnosed, undergo further laboratory tests, and proceed with consultations with internists (adjusted OR [95% CI] = 3.52 [1.97\u20136.32], 17.13 [5.74\u201351.11], and 6.38 [1.95\u201320.93], respectively).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Eosinophilia is commonly identified in periodic health examinations, and most primary physicians lack knowledge regarding the diagnostic work-up required to determine the cause of eosinophilia. Empirical anthelmintic therapy showed satisfactory efficacy for the management of eosinophilia in areas where parasite infection is endemic.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2478\/abm-2022-0030","type":"journal-article","created":{"date-parts":[[2023,6,16]],"date-time":"2023-06-16T03:38:48Z","timestamp":1686886728000},"page":"273-282","source":"Crossref","is-referenced-by-count":2,"title":["Prevalence and management of eosinophilia based on periodic health examinations in primary care clinics"],"prefix":"10.2478","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3386-242X","authenticated-orcid":false,"given":"Thareerat","family":"Ananchaisarp","sequence":"first","affiliation":[{"name":"Division of Family and Preventive Medicine, Faculty of Medicine , Prince of Songkla University , Songkhla , Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5821-4739","authenticated-orcid":false,"given":"Panya","family":"Chamroonkiadtikun","sequence":"additional","affiliation":[{"name":"Division of Family and Preventive Medicine, Faculty of Medicine , Prince of Songkla University , Songkhla , Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6526-9479","authenticated-orcid":false,"given":"Jakrawadee","family":"Julamanee","sequence":"additional","affiliation":[{"name":"Division of Internal Medicine, Faculty of Medicine , Prince of Songkla University , Songkhla , Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7048-5846","authenticated-orcid":false,"given":"Kewalee","family":"Perdvong","sequence":"additional","affiliation":[{"name":"Faculty of Medicine , Prince of Songkla University , Songkhla , Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5876-014X","authenticated-orcid":false,"given":"Thitawan","family":"Chimpalee","sequence":"additional","affiliation":[{"name":"Faculty of Medicine , Prince of Songkla University , Songkhla , Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2315-6345","authenticated-orcid":false,"given":"Nutnicha","family":"Rattanavirakul","sequence":"additional","affiliation":[{"name":"Faculty of Medicine , Prince of Songkla University , Songkhla , Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5470-2786","authenticated-orcid":false,"given":"Nattawat","family":"Leelarujijaroen","sequence":"additional","affiliation":[{"name":"Faculty of Medicine , Prince of Songkla University , Songkhla , Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9997-5235","authenticated-orcid":false,"given":"Tiprada","family":"Hathaipitak","sequence":"additional","affiliation":[{"name":"Faculty of Medicine , Prince of Songkla University , Songkhla , Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1134-8972","authenticated-orcid":false,"given":"Thanarat","family":"Tantinam","sequence":"additional","affiliation":[{"name":"Faculty of Medicine , Prince of Songkla University , Songkhla , Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2023,6,16]]},"reference":[{"key":"2026042708183321776_j_abm-2022-0030_ref_001","doi-asserted-by":"crossref","unstructured":"Butt NM, Lambert J, Ali S, Beer PA, Cross NC, Duncombe A, et al. 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