{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T22:24:44Z","timestamp":1787264684416,"version":"build-2736575974"},"reference-count":53,"publisher":"Walter de Gruyter GmbH","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Bowel-associated dermatosis\u2013arthritis syndrome (BADAS) is a rare neutrophilic dermatosis characterized by recurrent erythematous macules, papules or vesicopustules accompanied by fever, malaise, arthralgia and peripheral arthritis. Although originally described after intestinal bypass procedures, BA-DAS is increasingly recognized in inflammatory bowel disease (IBD), yet remains underdiagnosed and lacks practical guidance. We reviewed published IBD-associated BADAS cases to define clinical patterns and therapeutic options, and report two additional cases managed by an interdisciplinary team. Across the literature, 21 IBD-associated BADAS cases were identified, with a female predominance (65%) and a mean age at onset of 36.7 years; pediatric presentations accounted for 17%. Ulcerative colitis (12 cases) and Crohn\u2019s disease (10 cases) were the most frequent underlying conditions. BADAS was often diagnosed concurrently with IBD, indicating that the combination of cutaneous eruptions, joint inflammation and systemic symptoms should prompt gastrointestinal evaluation. Frequently reported abnormalities included leukocytosis, anemia and elevated inflammatory markers, and skin histopathology typically showed a neutrophilic dermatosis often with leukocytoclastic vasculitis. Case 1 (30-year-old woman with ulcerative colitis) achieved sustained remission with antibiotics, corticosteroid taper, cyclosporine induction and azathioprine maintenance. Case 2 (67-year-old man with Crohn\u2019s disease) responded to antibiotics followed by infliximab, with resolution of skin, joint and intestinal activity. We propose a pragmatic management approach integrating antibiotics, optimization of IBD therapy and early use of biologics (preferably anti-TNF) in severe or steroid-refractory disease.<\/jats:p>","DOI":"10.2478\/aite-2026-0010","type":"journal-article","created":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T18:59:28Z","timestamp":1771700368000},"source":"Crossref","is-referenced-by-count":1,"title":["Bowel-Associated Dermatosis and Arthritis Syndrome (BADAS) \u2013 A Literature Review With Diagnostic and Therapeutic Implications and a Report of Two Cases of BADAS Associated With Inflammatory Bowel Disease"],"prefix":"10.2478","volume":"74","author":[{"given":"Raman","family":"Nitskovich","sequence":"first","affiliation":[{"name":"Department of Dermatology, Center of Postgraduate Medical Education , National Medical Institute of Ministry of the Interior and Administration , Warsaw , Poland"},{"name":"Chair and Department of Dermatology and Pediatric Dermatology , Centre of Postgraduate Medical Education , Woloska 137 , Warsaw , Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aleksandra","family":"J\u00f3\u017awik","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Center of Postgraduate Medical Education , National Medical Institute of Ministry of the Interior and Administration , Warsaw , Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piotr","family":"Sobolewski","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Center of Postgraduate Medical Education , National Medical Institute of Ministry of the Interior and Administration , Warsaw , Poland"},{"name":"Chair and Department of Dermatology and Pediatric Dermatology , Centre of Postgraduate Medical Education , Woloska 137 , Warsaw , Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pawe\u0142","family":"G\u0142uszak","sequence":"additional","affiliation":[{"name":"Department of Dermatology, University Clinical Hospital , Poznan University of Medical Sciences , Pozna\u0144 , Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dagmara S.","family":"Mahadea","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Dietetics and Internal Medicine, University Clinical Hospital , Poznan University of Medical Sciences , Pozna\u0144 , Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irena","family":"Walecka","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Center of Postgraduate Medical Education , National Medical Institute of Ministry of the Interior and Administration , Warsaw , Poland"},{"name":"Chair and Department of Dermatology and Pediatric Dermatology , Centre of Postgraduate Medical Education , Woloska 137 , Warsaw , Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2026,2,21]]},"reference":[{"key":"2026082022004237443_j_aite-2026-0010_ref_001","doi-asserted-by":"crossref","unstructured":"Ahn C, Negus D, Huang W (2018) Pyoderma gangrenosum: A review of pathogenesis and treatment. 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