{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T07:02:24Z","timestamp":1777359744643,"version":"3.51.4"},"reference-count":29,"publisher":"Walter de Gruyter GmbH","issue":"3","license":[{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:bold>Objective.<\/jats:bold>\n                    The present study evaluates the occurrence of subacute thyroiditis in temporal connection with SARS-Cov2 vaccinations described in the literature last year and confirmed by our clinical routine.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods.<\/jats:bold>\n                    Systematic literature search in Medline for studies reporting diagnosis of subacute thyroiditis in temporal connection with vaccinations against Covid 19.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results.<\/jats:bold>\n                    The literature search yielded 24 relevant references out of which 22 were \u201ccase reports\u201d and two \u201cLetters to the Editor\u201d and encompassed 37 patient cases, in total. They had received a SARS-Cov2 vaccination shortly before the diagnosis (median interval to vaccination six days). In none of these cases, infection of the upper respiratory tract had previously been identified as a classic trigger of the disease. Newly occurring hyperthyroidism and increased laboratory signs of inflammation were described in 78% and 74% of cases, respectively. Atypical clinical pictures (asymptomatic, euthyroid, no inflammation marks) have been observed in both the literature and our patients suspected of thyroid cancer referred to surgery.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions.<\/jats:bold>\n                    In times of pandemics and the resulting vaccination, new rapidly occurring sonographic changes in the thyroid gland should be revaluated after 2\u20133 weeks, or recommended to undergo a fine-needle biopsy, in order to avoid unnecessary surgical interventions.\n                  <\/jats:p>","DOI":"10.2478\/enr-2022-0024","type":"journal-article","created":{"date-parts":[[2022,7,13]],"date-time":"2022-07-13T14:01:52Z","timestamp":1657720912000},"page":"227-231","source":"Crossref","is-referenced-by-count":2,"title":["Subacute thyroiditis after SARS-Cov2 vaccination: A review of the cases being described and personal experience"],"prefix":"10.2478","volume":"56","author":[{"given":"Costanza","family":"Chiapponi","sequence":"first","affiliation":[{"name":"Department of General, Visceral, Cancer and Transplant Surgery , University Clinic of Cologne , Cologne , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Faust","sequence":"additional","affiliation":[{"name":"Policlinic for Endocrinology, Diabetes and Prevention Medicine , University Clinic of Cologne , Cologne , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias","family":"Schmidt","sequence":"additional","affiliation":[{"name":"Department for Nuclear Medicine , University Clinic of Cologne , Cologne , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Thomas","sequence":"additional","affiliation":[{"name":"Department of General, Visceral, Cancer and Transplant Surgery , University Clinic of Cologne , Cologne , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne Maria","family":"Schultheis","sequence":"additional","affiliation":[{"name":"Institute for Pathology , University Clinic of Cologne , Cologne , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baki","family":"Akgul","sequence":"additional","affiliation":[{"name":"Institute for Virology , University of Cologne, Medical Faculty and University Hospital of Cologne , Cologne , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hakan","family":"Alakus","sequence":"additional","affiliation":[{"name":"Department of General, Visceral, Cancer and Transplant Surgery , University Clinic of Cologne , Cologne , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2022,7,13]]},"reference":[{"key":"2026042723193339000_j_enr-2022-0024_ref_001","doi-asserted-by":"crossref","unstructured":"Bornemann C, Woyk K, Bouter C. Case Report: Two Cases of Subacute Thyroiditis Following SARS-CoV-2 Vaccination. Front Med (Lausanne) 8, 737142, 2021.10.3389\/fmed.2021.737142842159934504856","DOI":"10.3389\/fmed.2021.737142"},{"key":"2026042723193339000_j_enr-2022-0024_ref_002","doi-asserted-by":"crossref","unstructured":"Chatzi S, Karampela A, Spiliopoulou C, Boutzios G. Subacute thyroiditis after SARS-CoV-2 vaccination: a report of two sisters and summary of the literature. Hormones (Athens) 21, 177\u2013179, 2021.10.1007\/s42000-021-00332-z853624834686971","DOI":"10.1007\/s42000-021-00332-z"},{"key":"2026042723193339000_j_enr-2022-0024_ref_003","doi-asserted-by":"crossref","unstructured":"Das L, Bhadada SK, Sood A. Post-COVID-vaccine autoimmune\/inflammatory syndrome in response to adjuvants (ASIA syndrome) manifesting as subacute thyroiditis. 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