{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T03:48:13Z","timestamp":1777348093302,"version":"3.51.4"},"reference-count":17,"publisher":"Walter de Gruyter GmbH","issue":"4","license":[{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:bold>Objective.<\/jats:bold>\n                    This study was aimed to evaluate the prevalence of Cushing\u2019s syndrome and the diagnostic performance of the 1 mg dexamethasone suppression test in class 3 obese patients.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods.<\/jats:bold>\n                    Anthropometric measurements and other laboratory data, including 1 mg dexamethasone suppression test of 753 class 3 obese patients, who applied to the Endocrinology and Metabolism Outpatient Clinic for the pre-bariatric surgery evaluation between 2011 and 2020, were evaluated retrospectively.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results.<\/jats:bold>\n                    An abnormal response to the 1 mg dexamethasone suppression test (cortisol \u22651.8 mcg\/dl) was observed in 24 patients and the presence of Cushing\u2019s syndrome was confirmed by additional tests in 6 patients. The prevalence of abnormal dexamethasone suppression test was 3.18% and the prevalence of Cushing\u2019s syndrome 0.79%. The specificity value was determined as 97.5% for 1 mg dexamethasone suppression test with cortisol threshold value \u22651.8 mcg\/dl.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions.<\/jats:bold>\n                    The prevalence of Cushing\u2019s syndrome was found to be low in class 3 obese patients and 1 mg of dexamethasone suppression test had a very sufficient performance for Cushing\u2019s syndrome screening in this patient group.\n                  <\/jats:p>","DOI":"10.2478\/enr-2022-0028","type":"journal-article","created":{"date-parts":[[2022,10,20]],"date-time":"2022-10-20T03:22:49Z","timestamp":1666236169000},"page":"265-270","source":"Crossref","is-referenced-by-count":3,"title":["Assessment of the diagnostic performance of the 1 mg dexamethasone suppression test in class 3 obese patients"],"prefix":"10.2478","volume":"56","author":[{"given":"Suleyman","family":"Baldane","sequence":"first","affiliation":[{"name":"Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine , Selcuk University , Konya , Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Celik","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine , Selcuk University , Konya , Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Levent","family":"Kebapcilar","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine , Selcuk University , Konya , Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suleyman Hilmi","family":"Ipekci","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine , Selcuk University , Konya , Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sedat","family":"Abusoglu","sequence":"additional","affiliation":[{"name":"Department Biochemistry, Faculty of Medicine , Selcuk University , Konya , Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huseyin","family":"Yilmaz","sequence":"additional","affiliation":[{"name":"Department of Surgery, Faculty of Medicine , Selcuk University , Konya , Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Husnu","family":"Alptekin","sequence":"additional","affiliation":[{"name":"Department of Surgery, Faculty of Medicine , Selcuk University , Konya , Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2022,10,20]]},"reference":[{"key":"2026042722155129591_j_enr-2022-0028_ref_001","doi-asserted-by":"crossref","unstructured":"Catargi B, Rigalleau V, Poussin A, Ronci-Chaix N, Bex V, Vergnot V, Gin H, Roger P, Tabarin A. 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