{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T03:50:41Z","timestamp":1777348241004,"version":"3.51.4"},"reference-count":28,"publisher":"Walter de Gruyter GmbH","issue":"1","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:bold>Objective.<\/jats:bold>\n                    Hyperparathyroidism is a prevalent disease with parathyroid adenomas being the most common cause. Surgical excision remains the standard treatment for parathyroid adenoma. Successful preoperative localization of the parathyroid adenoma could facilitate the decision regarding the extent of surgical exploration. The aim of the current study was to assess the correlation between the preoperative values of parathyroid hormone and ionized calcium with the adenoma weight and volume in patient with primary hyperparathyroidism caused by single-gland adenoma.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Patients and Methods.<\/jats:bold>\n                    We did this retrospective review for all patients who were diagnosed with primary hyperparathyroidism due to a solitary parathyroid adenoma in our general surgery department over 4 years. SPSS software was used to get the correlation coefficient between the peak preoperative levels of calcium and parathyroid hormone with the parathyroid adenoma weight and volume.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results.<\/jats:bold>\n                    Ninety-nine patients were included into the study. The average age at surgery was 62.65\u00b112.00 years. The correlation coefficient between the adenoma volume and weight with the preoperative ionized calcium level was weakly positive (r=0.329, p&lt;0.01) and (r=0.281, p=0.019), respectively, while the correlation with the preoperative parathyroid hormone level was stronger (r=0.708, p&lt;0.01) and (r=0.650, p&lt;0.01), respectively.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions.<\/jats:bold>\n                    The strong positive relationship between the preoperative parathyroid hormone and calcium levels with the parathyroid adenoma size and weight can help the surgeon to predict the volume of the involved gland and avoid an unnecessary dissection.\n                  <\/jats:p>","DOI":"10.2478\/enr-2023-0002","type":"journal-article","created":{"date-parts":[[2023,2,8]],"date-time":"2023-02-08T15:41:31Z","timestamp":1675870891000},"page":"12-17","source":"Crossref","is-referenced-by-count":5,"title":["Correlation between preoperative calcium and parathormone levels with parathyroid gland volume"],"prefix":"10.2478","volume":"57","author":[{"given":"Emad","family":"Rezkallah","sequence":"first","affiliation":[{"name":"General Surgery Department , James Cook University Hospital , England"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Elsaify","sequence":"additional","affiliation":[{"name":"Misr University for Science and Technology , Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ragai","family":"Hanna","sequence":"additional","affiliation":[{"name":"General Surgery Department , Faculty of Medicine Assiut University , Egypt ;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wael","family":"Elsaify","sequence":"additional","affiliation":[{"name":"General Surgery Department , James Cook University Hospital , England"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2023,2,8]]},"reference":[{"key":"2026042722160070632_j_enr-2023-0002_ref_001","unstructured":"Adami S, Marcocci C, Gatti D. Epidemiology of primary hyperparathyroidism in Europe. J Bone Miner Res 17, N18\u2013N23, 2002."},{"key":"2026042722160070632_j_enr-2023-0002_ref_002","unstructured":"Akerstrom G, Malmaeus J, Bergstrom R. Surgical anatomy of human parathyroid glands. Surgery 95, 14\u201321, 1984."},{"key":"2026042722160070632_j_enr-2023-0002_ref_003","doi-asserted-by":"crossref","unstructured":"Baloch ZW, LiVolsi VA. Pathology of the parathyroid glands in hyperparathyroidism. Semin Diagn Pathol 30, 165\u2013177, 2013.","DOI":"10.1053\/j.semdp.2013.06.003"},{"key":"2026042722160070632_j_enr-2023-0002_ref_004","doi-asserted-by":"crossref","unstructured":"Bindlish V, Freeman JL, Witterick IJ, Asa SL. Correlation of the biochemical parameters with single parathyroid adenoma weight and volume. Head Neck 24, 1000\u20131003, 2002.","DOI":"10.1002\/hed.10165"},{"key":"2026042722160070632_j_enr-2023-0002_ref_005","doi-asserted-by":"crossref","unstructured":"Botushanova AD, Botushanov NP, Yaneva MP. 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