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A total of 24 forty-day-old Kalimero-Super Master hybrid chickens were divided into 4 groups (n=6): the Fli group received Flimabend\n                    <jats:italic>per os<\/jats:italic>\n                    , 100 mg\/g suspension in 1.43 mg of active substance\/kg body weight during 7 day of experiment, Far group received Farmatan\n                    <jats:italic>per os<\/jats:italic>\n                    at 0.2 % concentration for 6 hours per day during 5 day (experimental days \u2013 from 3 to 7); the Far+Fli group received a combination of doses administered in the same way as for the first two groups; and control \u2013C group with no active substance administration. The results demonstrated mild increase of leukocytes, lymphocytes, monocytes, leucocyte common antigen CD45, IgM+ and IgA+ cells in peripheral blood after administration of Flimabend. Similarly, subpopulations of followed lymphocytes (CD3+, CD4+, CD8+, IgM+) were increased in the jejunum after application of that drug. On the other hand, administration of Farmatan revealed opposite effect on determined immunocompetent cells what proves anti-inflammatory effect. Morphology of villi was also negatively influenced by administration of Flimabend. Administration of Farmatan suggests also its preventive administration in chickens. This tanin-containing drug as plant natural product may be used due to its antibacterial activity and as promising alternative to conventional drug with possible antihelminthic effect.\n                  <\/jats:p>","DOI":"10.2478\/helm-2019-0029","type":"journal-article","created":{"date-parts":[[2019,11,6]],"date-time":"2019-11-06T04:30:49Z","timestamp":1573014649000},"page":"273-281","source":"Crossref","is-referenced-by-count":9,"title":["The influence of chestnut wood and flubendazole on morphology of small intestine and lymphocytes of peripheral blood, spleen and jejunum in broiler chickens"],"prefix":"10.2478","volume":"56","author":[{"suffix":"Jr.","given":"M.","family":"Levkut","sequence":"first","affiliation":[{"name":"Department of Pathological Anatomy and Pathological Physiology, University of Veterinary Medicine and Pharmacy , Komensk\u00e9ho 73 , Ko\u0161ice , Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Revajov\u00e1","sequence":"additional","affiliation":[{"name":"Department of Pathological Anatomy and Pathological Physiology, University of Veterinary Medicine and Pharmacy , Komensk\u00e9ho 73 , Ko\u0161ice , Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Levkutov\u00e1","sequence":"additional","affiliation":[{"name":"Department of Pathological Anatomy and Pathological Physiology, University of Veterinary Medicine and Pharmacy , Komensk\u00e9ho 73 , Ko\u0161ice , Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Seleck\u00e1","sequence":"additional","affiliation":[{"name":"Medivet , \u0160kolsk\u00e1 457\/23 , Dobr\u00e1 Niva , Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z.","family":"\u0160ev\u010d\u00edkov\u00e1","sequence":"additional","affiliation":[{"name":"Department of Pathological Anatomy and Pathological Physiology, University of Veterinary Medicine and Pharmacy , Komensk\u00e9ho 73 , Ko\u0161ice , Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Karaffov\u00e1","sequence":"additional","affiliation":[{"name":"Department of Pathological Anatomy and Pathological Physiology, University of Veterinary Medicine and Pharmacy , Komensk\u00e9ho 73 , Ko\u0161ice , Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Sr.","given":"M.","family":"Levkut","sequence":"additional","affiliation":[{"name":"Department of Pathological Anatomy and Pathological Physiology, University of Veterinary Medicine and Pharmacy , Komensk\u00e9ho 73 , Ko\u0161ice , Slovakia"},{"name":"Institute of Neuroimmunology, Slovak Academy of Science , D\u00fabravsk\u00e1 cesta 9, 845 10 Bratislava , Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2019,11,6]]},"reference":[{"key":"2026081304013838207_j_helm-2019-0029_ref_001_w2aab3b7b5b1b6b1ab1b7b1Aa","doi-asserted-by":"crossref","unstructured":"Awad, W.A., Hess, C., Hess, M. 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