{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T02:13:18Z","timestamp":1788142398845,"version":"build-2803163510"},"reference-count":17,"publisher":"Walter de Gruyter GmbH","issue":"4","license":[{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:bold>Purpose<\/jats:bold>\n                    : Several studies show conflicting results regarding the prognosis and predictors of the outcome of critically ill patients with a solid malignancy. This study aims to determine the outcome of critically ill patients, admitted to a hospital, with a solid malignancy and the factors associated with the outcomes.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods and Materials<\/jats:bold>\n                    : All patients with a solid malignancy admitted to an intensive care unit (ICU) at a tertiary academic medical center were enrolled. Clinical data upon admission and during ICU stay were collected. Hospital, ICU, and six months outcomes were documented.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results<\/jats:bold>\n                    : There were 252 patients with a solid malignancy during the study period. Urogenital malignancies were the most common (26.3%) followed by lung cancer (23.5%). Acute respiratory failure was the most common ICU diagnosis (51.6%) followed by sepsis in 46%. ICU mortality and hospital mortality were 21.8% and 34.3%. Six months mortality was 38.4%. Using multivariate analysis, acute kidney injury, OR 2.82, 95% CI 1.50-5.32 and P=0.001, use of mechanical ventilation, OR 2.67 95% CI 1.37 \u2013 5.19 and P=0.004 and performance status of \u22652 with OR of 3.05, 95% CI of 1.5-6.2 and P= 0.002 were associated with hospital mortality. There were no differences in outcome between African American patients (53% of all patients) and other races.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusion<\/jats:bold>\n                    : This study reports encouraging survival rates in patients with a solid malignancy who are admitted to ICU. Patients with a poor baseline performance status require mechanical ventilation or develop acute renal failure have worse outcomes.\n                  <\/jats:p>","DOI":"10.2478\/jccm-2018-0019","type":"journal-article","created":{"date-parts":[[2018,11,17]],"date-time":"2018-11-17T04:32:39Z","timestamp":1542429159000},"page":"137-142","source":"Crossref","is-referenced-by-count":11,"title":["Factors Associated with Mortality in Patients with a Solid Malignancy Admitted to the Intensive Care Unit - A Prospective Observational Study"],"prefix":"10.2478","volume":"4","author":[{"given":"Pascal","family":"Kingah","sequence":"first","affiliation":[{"name":"Division of Pulmonary, Critical Care and Sleep Medicine , Wayne State University School of Medicine , 3990 John R, 3 Hudson, Detroit MI 48201 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nasser","family":"Alzubaidi","sequence":"additional","affiliation":[{"name":"Division of Pulmonary, Critical Care and Sleep Medicine , Wayne State University School of Medicine , 3990 John R, 3 Hudson, Detroit MI 48201 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jihane Zaza Dit","family":"Yafawi","sequence":"additional","affiliation":[{"name":"Division of Pulmonary, Critical Care and Sleep Medicine , Wayne State University School of Medicine , 3990 John R, 3 Hudson, Detroit MI 48201 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emad","family":"Shehada","sequence":"additional","affiliation":[{"name":"Division of Pulmonary, Critical Care and Sleep Medicine , Wayne State University School of Medicine , 3990 John R, 3 Hudson, Detroit MI 48201 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khaled","family":"Alshabani","sequence":"additional","affiliation":[{"name":"Division of Pulmonary, Critical Care and Sleep Medicine , Wayne State University School of Medicine , 3990 John R, 3 Hudson, Detroit MI 48201 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayman O.","family":"Soubani","sequence":"additional","affiliation":[{"name":"Division of Pulmonary, Critical Care and Sleep Medicine , Wayne State University School of Medicine , 3990 John R, 3 Hudson, Detroit MI 48201 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2018,11,14]]},"reference":[{"key":"2025012821053509031_j_jccm-2018-0019_ref_001_w2aab3b7b3b1b6b1ab1ab1Aa","doi-asserted-by":"crossref","unstructured":"1. 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