{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T16:32:24Z","timestamp":1790785944711,"version":"4.1.0"},"reference-count":16,"publisher":"Walter de Gruyter GmbH","issue":"3","license":[{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,8,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_jccm-2019-0013_s_005_w2aab3b7b1b1b6b1aab1c17b1Aa\">\n                    <jats:title id=\"d1482944e4206_w2aab3b7b1b1b6b1aab1c17b1aAa\">Introduction<\/jats:title>\n                    <jats:p>Human brucellosis, the most prevalent zoonotic disease worldwide, is a systemic infection which can involve several organs. Among musculoskeletal complaints, spondylitis is the most frequent complication of brucellosis and primarily affects the lumbar and thoracic vertebrae. The involvement of the cervical spine is infrequent.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jccm-2019-0013_s_006_w2aab3b7b1b1b6b1aab1c17b2Aa\">\n                    <jats:title id=\"d1482944e4214_w2aab3b7b1b1b6b1aab1c17b2aAa\">Case report<\/jats:title>\n                    <jats:p>This case report concerns an unusual case of cervical spine spondylitis with an epidural abscess due to Brucella in a 43-year-old man. The diagnosis was based on the patient being domiciled in an endemic region, his symptoms and his occupation. Clinical outcomes improved following antimicrobial therapy of rifampin, doxycycline, and gentamycin, and were confirmed radiologically.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jccm-2019-0013_s_007_w2aab3b7b1b1b6b1aab1c17b3Aa\">\n                    <jats:title id=\"d1482944e4222_w2aab3b7b1b1b6b1aab1c17b3aAa\">Conclusion<\/jats:title>\n                    <jats:p>Early diagnosis and treatment are crucial for these patients. The timely commencement of medical treatment can help prevent surgery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2478\/jccm-2019-0013","type":"journal-article","created":{"date-parts":[[2019,8,12]],"date-time":"2019-08-12T05:31:10Z","timestamp":1565587870000},"page":"103-106","source":"Crossref","is-referenced-by-count":15,"title":["Cervical Spine Spondylitis with an Epidural Abscess in a Patient with Brucellosis: A Case Report"],"prefix":"10.2478","volume":"5","author":[{"given":"Mohammad Reza Hasanjani","family":"Roushan","sequence":"first","affiliation":[{"name":"Infectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences , Babol , I.R. Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soheil","family":"Ebrahimpour","sequence":"additional","affiliation":[{"name":"Infectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences , Babol , I.R. Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeinab Mohseni","family":"Afshar","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Kermanshah University of Medical Sciences , Kermanshah , Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arefeh","family":"Babazadeh","sequence":"additional","affiliation":[{"name":"Infectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences , Babol , I.R. Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2019,8,9]]},"reference":[{"key":"2026021210064713498_j_jccm-2019-0013_ref_001_w2aab3b7b1b1b6b1ab1b6b1Aa","doi-asserted-by":"crossref","unstructured":"Herrick JA, Lederman RJ, Sullivan B, Powers JH, Palmore TN. Brucella arteritis: clinical manifestations, treatment, and prognosis. Lancet Infect Dis. 2014;14(6):520-6.","DOI":"10.1016\/S1473-3099(13)70270-6"},{"key":"2026021210064713498_j_jccm-2019-0013_ref_002_w2aab3b7b1b1b6b1ab1b6b2Aa","doi-asserted-by":"crossref","unstructured":"Tuon FF, Gondolfo RB, Cerchiari N. Human-to-human transmission of Brucella - a systematic review. Trop Med Int Health. 2017;22(5):539-46.","DOI":"10.1111\/tmi.12856"},{"key":"2026021210064713498_j_jccm-2019-0013_ref_003_w2aab3b7b1b1b6b1ab1b6b3Aa","unstructured":"Hasanjani MR, Bayani M, Soleimani SA, Mohammadnia-Afrouzi M, Nouri H, Ebrahimpour S. Evaluation of CD4+ CD25+ FoxP3+ regulatory T cells during treatment of patients with brucellosis. J Biol Regul Homeost Agents. 2016;30(3):675-82."},{"key":"2026021210064713498_j_jccm-2019-0013_ref_004_w2aab3b7b1b1b6b1ab1b6b4Aa","unstructured":"Ebrahimpour S, Bayani M, Moulana Z, Hasanjani Roushan MR. Skeletal complications of brucellosis: A study of 464 cases in Babol, Iran. Caspian J Intern Med. 2017;8(1):44-8."},{"key":"2026021210064713498_j_jccm-2019-0013_ref_005_w2aab3b7b1b1b6b1ab1b6b5Aa","doi-asserted-by":"crossref","unstructured":"Kutlu SS, Kutlu M, Tuzun T, Ozdemir K. Spondylodiscitis: a common complication of brucellosis. J Infect Dev Countries. 2018;12(07):550-6.","DOI":"10.3855\/jidc.10557"},{"key":"2026021210064713498_j_jccm-2019-0013_ref_006_w2aab3b7b1b1b6b1ab1b6b6Aa","doi-asserted-by":"crossref","unstructured":"Lampropoulos C, Kamposos P, Papaioannou I, Niarou V. Cervical epidural abscess caused by brucellosis. BMJ Case Rep. 2012;2012:bcr2012007070.","DOI":"10.1136\/bcr-2012-007070"},{"key":"2026021210064713498_j_jccm-2019-0013_ref_007_w2aab3b7b1b1b6b1ab1b6b7Aa","doi-asserted-by":"crossref","unstructured":"Re\u015forlu H, Sa\u00e7ar S, Inceer B\u015e, et al. Cervical spondylitis and epidural abscess caused by brucellosis: a case report and literature review. Folia Med. 2016;58(4):289-92.","DOI":"10.1515\/folmed-2016-0035"},{"key":"2026021210064713498_j_jccm-2019-0013_ref_008_w2aab3b7b1b1b6b1ab1b6b8Aa","doi-asserted-by":"crossref","unstructured":"Turan H, Serefhanoglu K, Karadeli E, Togan T, Arslan H. Osteoarticular involvement among 202 brucellosis cases identified in Central Anatolia region of Turkey. Intern Med. 2011;50(5):421-8.","DOI":"10.2169\/internalmedicine.50.4700"},{"key":"2026021210064713498_j_jccm-2019-0013_ref_009_w2aab3b7b1b1b6b1ab1b6b9Aa","doi-asserted-by":"crossref","unstructured":"Lim K-B, Kwak Y-G, Kim D-Y, Kim Y-S, Kim J-A. Back pain secondary to Brucella spondylitis in the lumbar region. Ann Rehabil Med. 2012;36(2):282-6.","DOI":"10.5535\/arm.2012.36.2.282"},{"key":"2026021210064713498_j_jccm-2019-0013_ref_010_w2aab3b7b1b1b6b1ab1b6c10Aa","doi-asserted-by":"crossref","unstructured":"Yang B, Hu H, Chen J, He X, Li H. The Evaluation of the Clinical, Laboratory, and Radiological Findings of 16 Cases of Brucellar Spondylitis. BioMed Res Int. 2016;2016:6.","DOI":"10.1155\/2016\/8903635"},{"key":"2026021210064713498_j_jccm-2019-0013_ref_011_w2aab3b7b1b1b6b1ab1b6c11Aa","unstructured":"Ural O, S\u00fcmer \u015e, Demir NA, Dikici N, Firat V. Isolated Cervical Spondylodiscitis Due to Brucellosis: A Case Report. J Physic Med Rehabil Sci. 2013;16(3)."},{"key":"2026021210064713498_j_jccm-2019-0013_ref_012_w2aab3b7b1b1b6b1ab1b6c12Aa","unstructured":"Hasanjani Roushan MR, Ebrahimpour S. Human brucellosis: An overview. Caspian J Intern Med. 2015;6(1):46."},{"key":"2026021210064713498_j_jccm-2019-0013_ref_013_w2aab3b7b1b1b6b1ab1b6c13Aa","doi-asserted-by":"crossref","unstructured":"Garg RK, Somvanshi DS. Spinal tuberculosis: a review. J Spinal Cord Med. 2011;34(5):440-54.","DOI":"10.1179\/2045772311Y.0000000023"},{"key":"2026021210064713498_j_jccm-2019-0013_ref_014_w2aab3b7b1b1b6b1ab1b6c14Aa","doi-asserted-by":"crossref","unstructured":"Gangi SMS, Hasanjani Roushan MR, Janmohammadi N, Mehraeen R, Amiri MJS, Khalilian E. Outcomes of treatment in 50 cases with spinal brucellosis in Babol, Northern Iran. J Infect Dev Countries. 2012;6(09):654-9.","DOI":"10.3855\/jidc.2175"},{"key":"2026021210064713498_j_jccm-2019-0013_ref_015_w2aab3b7b1b1b6b1ab1b6c15Aa","doi-asserted-by":"crossref","unstructured":"Lee HJ, Hur JW, Lee JW, Lee SR. Brucellar spondylitis.J Korean Neurosurg Soc. 2008;44(4):277-9.","DOI":"10.3340\/jkns.2008.44.4.277"},{"key":"2026021210064713498_j_jccm-2019-0013_ref_016_w2aab3b7b1b1b6b1ab1b6c16Aa","unstructured":"Hasanjani Roushan MR, Gangi SMS, Janmohammadi N. Update on the treatment of adult cases of human brucellosis. Arch Clin Infect Dis. 2008;3(3):167-73."}],"container-title":["The Journal of Critical Care Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/content.sciendo.com\/view\/journals\/jccm\/5\/3\/article-p103.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.sciendo.com\/pdf\/10.2478\/jccm-2019-0013","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T10:07:14Z","timestamp":1770890834000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.sciendo.com\/article\/10.2478\/jccm-2019-0013"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7,1]]},"references-count":16,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2019,8,9]]},"published-print":{"date-parts":[[2019,8,9]]}},"alternative-id":["10.2478\/jccm-2019-0013"],"URL":"https:\/\/doi.org\/10.2478\/jccm-2019-0013","relation":{},"ISSN":["2393-1817"],"issn-type":[{"value":"2393-1817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,7,1]]}}}