{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T02:24:43Z","timestamp":1776133483817,"version":"3.50.1"},"reference-count":20,"publisher":"Walter de Gruyter GmbH","issue":"2","license":[{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,5,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_jccm-2022-0002_s_005\">\n                  <jats:title>Introduction<\/jats:title>\n                  <jats:p>Takotsubo cardiomyopathy is a rare reversible type of heart failure, often precipitated by emotional stress; other risk factors include intracranial bleeding, ischemic stroke, sepsis, major surgery, pheochromocytoma. The clinical, electrical and blood sample analysis features resemble those of a myocardial infarction- however, they occur in the absence of angiographic coronary filling defects.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jccm-2022-0002_s_006\">\n                  <jats:title>Case presentation<\/jats:title>\n                  <jats:p>A 61-year-old male patient, 71 kg, 175 cm, underwent liver transplantation for Child-Pugh B cirrhosis secondary to mixed viral hepatitis (B and D). His medical records revealed mild mitral, aortic, and tricuspid insufficiencies and heart failure with preserved ejection fraction. An initially uneventful perioperative stage was succeeded by cardiogenic shock (cardiac index \u2013 1.2 l\/min\/ sqm), which the patient developed 24 hours after the intervention. Elevated cardiac markers and ECG abnormalities showing ST-T changes in the V2-V5 leads were additionally noted. Transesophageal echocardiography (TEE) revealed an acute onset reduction in the left ventricular systolic function secondary to basal hypokinesia. No coronary obstruction was detected by percutaneous angiography. The above findings lead to the diagnosis of reverseTakotsubo cardiomyopathy. Further, the patient developed acute kidney injury and liver graft failure, succumbing within 48 hours after the surgical procedure.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jccm-2022-0002_s_007\">\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>We report a rare case of reverse Takotsubo cardiomyopathy in a male patient after orthotopic liver transplant.<\/jats:p>\n               <\/jats:sec>","DOI":"10.2478\/jccm-2022-0002","type":"journal-article","created":{"date-parts":[[2022,5,11]],"date-time":"2022-05-11T20:30:53Z","timestamp":1652301053000},"page":"117-122","source":"Crossref","is-referenced-by-count":3,"title":["Reverse Takotsubo cardiomyopathy after orthotopic liver transplantation. A case report"],"prefix":"10.2478","volume":"8","author":[{"given":"Lucian","family":"Mihalcea","sequence":"first","affiliation":[{"name":"Department of Anesthesiology and Intensive Care I, Fundeni Clinical Institute , Bucharest , Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isac","family":"Sebastian","sequence":"additional","affiliation":[{"name":"Carol Davila University of Medicine and Pharmacy Faculty of Pharmacy , Bucharest , Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mihail","family":"Simion-Cotorogea","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Intensive Care I, Fundeni Clinical Institute , Bucharest , Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Artsiom","family":"Klimko","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular Neuro-Oncology, Department of Neurology, University Hospital Zurich and University of Zurich , Zurich , Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriela","family":"Droc","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Intensive Care I, Fundeni Clinical Institute , Bucharest , Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2022,5,12]]},"reference":[{"key":"2024042805492983974_j_jccm-2022-0002_ref_001","unstructured":"Previtali M, Repetto A, Camporotondo R, et al. Clinical characteristics and outcome of left ventricular ballooning syndrome in a European population. Am J Cardiol. Jan 2011;107(1):120-5."},{"key":"2024042805492983974_j_jccm-2022-0002_ref_002","doi-asserted-by":"crossref","unstructured":"Pelliccia F, Kaski JC, Crea F, Camici PG. Pathophysiology of Takotsubo Syndrome. Circulation. 2017;135(24):2426-2441.","DOI":"10.1161\/CIRCULATIONAHA.116.027121"},{"key":"2024042805492983974_j_jccm-2022-0002_ref_003","doi-asserted-by":"crossref","unstructured":"Lyon AR, Rees PS, Prasad S, et al. Stress (Takotsubo) cardiomyopathy-a novel pathophysiological hypothesis to explain catecholamine-induced acute myocardial stunning. Nat Clin Pract Cardiovasc Med. Jan 2008;5(1):22-9.","DOI":"10.1038\/ncpcardio1066"},{"key":"2024042805492983974_j_jccm-2022-0002_ref_004","doi-asserted-by":"crossref","unstructured":"Y-Hassan, S., Tornvall, P. Epidemiology, pathogenesis, and management of takotsubo syndrome. Clin Auton Res. 2018;28(1):53\u201365.","DOI":"10.1007\/s10286-017-0465-z"},{"key":"2024042805492983974_j_jccm-2022-0002_ref_005","doi-asserted-by":"crossref","unstructured":"Sharkey SW, Windenburg DC, Lesser JR, et al. Natural history and expansive clinical profile of stress (tako-tsubo) cardiomyopathy. J Am Coll Cardiol. Jan 2010;55(4):333-41.","DOI":"10.1016\/j.jacc.2009.08.057"},{"key":"2024042805492983974_j_jccm-2022-0002_ref_006","doi-asserted-by":"crossref","unstructured":"Endo S, Suzuki Y, Takahashi G, et al. Presepsin as a powerful monitoring tool for the prognosis and treatment of sepsis: a multicenter prospective study. J Infect Chemother. Epub 2013 Dec 11. Jan 2014;20(1):30-4.","DOI":"10.1016\/j.jiac.2013.07.005"},{"key":"2024042805492983974_j_jccm-2022-0002_ref_007","doi-asserted-by":"crossref","unstructured":"Masson S, Caironi P, Spanuth E, et al. Presepsin (soluble CD14 subtype) and procalcitonin levels for mortality prediction in sepsis: data from the Albumin Italian Outcome Sepsis trial. Crit Care. Jan 2014; 18(1):R6.","DOI":"10.1186\/cc13183"},{"key":"2024042805492983974_j_jccm-2022-0002_ref_008","doi-asserted-by":"crossref","unstructured":"Litton E, Morgan M. The PiCCO monitor: a review. Anaesth Intensive Care. May 2012;40(3):393-409.","DOI":"10.1177\/0310057X1204000304"},{"key":"2024042805492983974_j_jccm-2022-0002_ref_009","doi-asserted-by":"crossref","unstructured":"Redfors B, Shao Y, Lyon AR, et al. Diagnostic criteria for takotsubo syndrome: a call for consensus. Int J Cardiol. Epub 2014 Jul 8. Sep 2014;176(1):274-6.","DOI":"10.1016\/j.ijcard.2014.06.094"},{"key":"2024042805492983974_j_jccm-2022-0002_ref_010","doi-asserted-by":"crossref","unstructured":"Ghadri JR, Cammann VL, Jurisic S, et al. A novel clinical score (InterTAK Diagnostic Score) to differentiate takotsubo syndrome from acute coronary syndrome: results from the International Takotsubo Registry. Eur J Heart Fail. 2017;19(8):1036-1042.","DOI":"10.1002\/ejhf.683"},{"key":"2024042805492983974_j_jccm-2022-0002_ref_011","doi-asserted-by":"crossref","unstructured":"Templin C, Ghadri J R, Diekmann J, et al. (2015). Clinical features and outcomes of takotsubo (stress) cardiomyopathy. New Eng J Med. Sep 2015;373(10), 929-938.","DOI":"10.1056\/NEJMoa1406761"},{"key":"2024042805492983974_j_jccm-2022-0002_ref_012","doi-asserted-by":"crossref","unstructured":"Awad HH, McNeal AR, Goyal H. Reverse Takotsubo cardiomyopathy: a comprehensive review. Ann Transl Med. 2018;6(23):460.","DOI":"10.21037\/atm.2018.11.08"},{"key":"2024042805492983974_j_jccm-2022-0002_ref_013","doi-asserted-by":"crossref","unstructured":"Stiermaier T, Eitel C, Desch S, et al. Incidence, determinants and prognostic relevance of cardiogenic shock in patients with Takotsubo cardiomyopathy. Eur Heart J Acute Cardiovasc Care. 2016;5(6):489-496.","DOI":"10.1177\/2048872615612456"},{"key":"2024042805492983974_j_jccm-2022-0002_ref_014","doi-asserted-by":"crossref","unstructured":"Frangieh AH, Obeid S, Ghadri JR, et al. ECG Criteria to Differentiate Between Takotsubo (Stress) Cardiomyopathy and Myocardial Infarction. J Am Heart Assoc. Jun 2016;5(6):e003418.","DOI":"10.1161\/JAHA.116.003418"},{"key":"2024042805492983974_j_jccm-2022-0002_ref_015","doi-asserted-by":"crossref","unstructured":"Lanza GA, Careri G, Stazi A, et al. Clinical Spectrum and Outcome of Patients With Non-ST-Segment Elevation Acute Coronary Syndrome and No Obstructive Coronary Atherosclerosis. Circ J. 2016;80(7):1600-1606.","DOI":"10.1253\/circj.CJ-16-0145"},{"key":"2024042805492983974_j_jccm-2022-0002_ref_016","doi-asserted-by":"crossref","unstructured":"Pelliccia F, Parodi G, Greco C, et al. Comorbidities frequency in Takotsubo syndrome: an international collaborative systematic review including 1109 patients. Am J Med. 2015;128(6):654. e11-654.e6.54E19.","DOI":"10.1016\/j.amjmed.2015.01.016"},{"key":"2024042805492983974_j_jccm-2022-0002_ref_017","doi-asserted-by":"crossref","unstructured":"Lu X, Li P, Teng C, et al. Prognostic factors of Takotsubo cardiomyopathy: a systematic review. ESC Heart Fail. 2021;8(5):3663-3689.","DOI":"10.1002\/ehf2.13531"},{"key":"2024042805492983974_j_jccm-2022-0002_ref_018","doi-asserted-by":"crossref","unstructured":"Palanisamy AP, Nadig SN, Chedister GR, et al. Use of intraaortic counterpulsation in cardiogenic shock post-liver transplantation. Clin Transplant. Epub 2017 Jun 5. Jul 2017;31(7).","DOI":"10.1111\/ctr.13002"},{"key":"2024042805492983974_j_jccm-2022-0002_ref_019","doi-asserted-by":"crossref","unstructured":"Andrei S, Isac S, Carstea M, et al. Isolated liver trauma: A clinical perspective in a non-emergency center for liver surgery. Exp Ther Med. Epub Nov 11 2021. 2022;23,39.","DOI":"10.3892\/etm.2021.10961"},{"key":"2024042805492983974_j_jccm-2022-0002_ref_020","doi-asserted-by":"crossref","unstructured":"Botea F, Ionescu M, Bra\u015foveanu V, et al. Liver Resections in a High-Volume Center: From Standard Procedures to Extreme Surgery and Ultrasound-guided Resections. Chirurgia. 2017 May-Jun;112(3):259-277.","DOI":"10.21614\/chirurgia.112.3.259"}],"container-title":["The Journal of Critical Care Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.sciendo.com\/pdf\/10.2478\/jccm-2022-0002","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,28]],"date-time":"2024-04-28T05:49:46Z","timestamp":1714283386000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.sciendo.com\/article\/10.2478\/jccm-2022-0002"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,1]]},"references-count":20,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2022,5,12]]},"published-print":{"date-parts":[[2022,5,12]]}},"alternative-id":["10.2478\/jccm-2022-0002"],"URL":"https:\/\/doi.org\/10.2478\/jccm-2022-0002","relation":{},"ISSN":["2393-1817"],"issn-type":[{"value":"2393-1817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,1]]}}}