{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,1,10]],"date-time":"2024-01-10T11:40:52Z","timestamp":1704886852143},"reference-count":10,"publisher":"Walter de Gruyter GmbH","issue":"3","license":[{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,10,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Lactic acidosis results from an acid-base balance disorder of the body due to an excess of lactic acid. It is frequently found in critically ill patients admitted to the intensive care. The most common cause is type A, found in pathologies such as cardiogenic, septic and hypovolemic shock, trauma and severe hypoxemia. The type B is less common and arises without evidence of tissue hypoperfusion or shock. Divers etiologies have been described for this type of hyperlactatemia: Grand Mal seizures, liver failure, hematologic malignancies, congenital enzyme deficiencies, thiamine deficiencies and diabetes mellitus and also alcohol abuse, which may induce a lactic acid under-use or an increased production. The authors describe a rare complication of type 1 Diabetes Mellitus (T1DM), leading to a major and persistent expression of a type B lactic acidosis during ketoacidosis.<\/jats:p>","DOI":"10.2478\/jtim-2019-0024","type":"journal-article","created":{"date-parts":[[2019,10,12]],"date-time":"2019-10-12T09:31:21Z","timestamp":1570872681000},"page":"115-117","source":"Crossref","is-referenced-by-count":6,"title":["Elevated lactic acid during ketoacidosis: pathophysiology and management"],"prefix":"10.2478","volume":"7","author":[{"given":"Hamda Houssein","family":"Ahmed","sequence":"first","affiliation":[{"name":"Intensive Care Unit, CHU Brugmann, Free University of Brussels ULB (ULB) , Brussels , Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"De Bels","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, CHU Brugmann, Free University of Brussels ULB (ULB) , Brussels , Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachid","family":"Attou","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, CHU Brugmann, Free University of Brussels ULB (ULB) , Brussels , Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick M.","family":"Honore","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, CHU Brugmann, Free University of Brussels ULB (ULB) , Brussels , Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebastien","family":"Redant","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, CHU Brugmann, Free University of Brussels ULB (ULB) , Brussels , Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2019,10,12]]},"reference":[{"key":"2023042508090655560_j_jtim-2019-0024_ref_001_w2aab3b7b8b1b6b1ab1b6b1Aa","doi-asserted-by":"crossref","unstructured":"Deemer KS, Alvarez GF. A rare case of persistent lactic acidosis in the ICU: glycogenic hepatopathy and Mauriac Syndrome Case Rep Crit Care 2016; 2016: 6072909.","DOI":"10.1155\/2016\/6072909"},{"key":"2023042508090655560_j_jtim-2019-0024_ref_002_w2aab3b7b8b1b6b1ab1b6b2Aa","doi-asserted-by":"crossref","unstructured":"van den Nouland DP, Brouwers MC, Stassen PM. Prognostic value of plasma lactate levels in a retrospective cohort presenting at a university hospital emergency department. BMJ Open 2017; 30: e011450.","DOI":"10.1136\/bmjopen-2016-011450"},{"key":"2023042508090655560_j_jtim-2019-0024_ref_003_w2aab3b7b8b1b6b1ab1b6b3Aa","doi-asserted-by":"crossref","unstructured":"Kraut JA, Madias NE. Lactic Acidosis. N Engl J Med 2014; 371: 2309\u201319.","DOI":"10.1056\/NEJMra1309483"},{"key":"2023042508090655560_j_jtim-2019-0024_ref_004_w2aab3b7b8b1b6b1ab1b6b4Aa","unstructured":"Mauriac P. 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