{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T07:28:19Z","timestamp":1761895699430},"reference-count":72,"publisher":"Polish Academy of Sciences Chancellery","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This paper describes a model of cell death, called autophagy, one among other typical and atypical processes of cell death. This phenomenon is present in the organism, from conception until death, and is conditioned by many genes of ATG family, or mTOR kinase and specific proteins, like BNIP3. This process plays a very important role not only in physiological functions of the organism but also in pathological, such as Alzheimer or Huntington disease, as well as diseases caused by viruses.<\/jats:p>","DOI":"10.2478\/pjvs-2013-0026","type":"journal-article","created":{"date-parts":[[2013,5,30]],"date-time":"2013-05-30T20:41:06Z","timestamp":1369946466000},"page":"173-180","source":"Crossref","is-referenced-by-count":7,"title":["Autophagy in physiological and pathological processes \u2013 selected aspects"],"prefix":"10.24425","volume":"16","author":[{"given":"P.","family":"Nied\u017awiedzka-Rystwej","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Tokarz-Deptu\u0142a","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Deptu\u0142a","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"37468","reference":[{"key":"ref331","first-page":"150","article-title":"tuberculosis DNA targets bacteria for autophagy by activating the host DNA - sensing pathway","author":"Watson RO","year":"2012","journal-title":"PS Cell"},{"key":"ref341","doi-asserted-by":"crossref","first-page":"7448","DOI":"10.1128\/JVI.00024-10","article-title":"Enhancement of autophagy during lytic replication by the Kaposi s sarcoma - associated herpesvirus replication and transcription activator","author":"Wen","year":"2010","journal-title":"J Virol"},{"key":"ref61","first-page":"1412","article-title":"in the remodeling of bovine mammary gland biology","author":"Gajewska","year":"2007","journal-title":"Autophagy Med Weter"},{"key":"ref321","first-page":"129","article-title":"pathophysiology","author":"Uchiyama","year":"2008","journal-title":"Autophagy physiology Histochem Cell Biol"},{"key":"ref701","doi-asserted-by":"crossref","first-page":"7448","DOI":"10.1128\/JVI.00024-10","article-title":"Enhancement of autophagy during lytic replication by the Kaposi s sarcoma - associated herpesvirus replication and transcription activator","author":"Wen","year":"2010","journal-title":"J Virol"},{"key":"ref101","doi-asserted-by":"crossref","first-page":"9349","DOI":"10.1158\/0008-5472.CAN-06-1597","article-title":"in cancer good bad or both","author":"Hippert","year":"2006","journal-title":"PS Autophagy Cancer Res"},{"key":"ref121","first-page":"13","article-title":"- the tool of cancer cell survival or death","volume":"32","author":"Lamparska","year":"2005","journal-title":"Autophagy"},{"key":"ref401","first-page":"23","article-title":"Role of autophagy in the host response to microbial infection and potential for therapy","author":"Fabri","year":"2011","journal-title":"Curr Opin Immunol"},{"key":"ref141","first-page":"132","article-title":"in the pathogenesis of disease","author":"Levine","year":"2008","journal-title":"Autophagy Cell"},{"key":"ref221","first-page":"455","article-title":"an important immunological phenomenon","author":"Nied\u017awiedzka","year":"2009","journal-title":"Autophagy"},{"key":"ref601","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/j.it.2012.06.003","article-title":"nz in the regulation of pathogen replication and adaptive immunity","author":"Randow","year":"2012","journal-title":"Autophagy Trends Immunol"},{"key":"ref241","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/j.it.2012.06.003","article-title":"nz in the regulation of pathogen replication and adaptive immunity","author":"Randow","year":"2012","journal-title":"Autophagy Trends Immunol"},{"key":"ref111","first-page":"185","article-title":"regulates metabolism during effector activation","author":"Hubbard","year":"2010","journal-title":"energy cell J Immunol"},{"key":"ref181","first-page":"351","article-title":"in viral and bacterial infections molecular roulette","author":"Matryniszyn","year":"2008","journal-title":"Autophagy"},{"key":"ref301","first-page":"420","article-title":"The types of cell death","author":"St\u0119pie\u0144","year":"2007"},{"key":"ref591","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.mib.2005.12.007","article-title":"Bacterial evasion of the autophagic defense system","author":"Ogawa","year":"2006","journal-title":"Curr Opin Microbiol"},{"key":"ref211","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.1038\/cdd.2012.52","article-title":"The role of autophagy in the pathogenesis of glycogen storage disease type II","volume":"19","author":"Nascimbeni","year":"2012","journal-title":"Cell Death Differ"},{"key":"ref561","first-page":"187","article-title":"- mediated dendritic cell activation is essential for innate cytokine production and APC function with respiratory syncytial virus responses","author":"Morris","year":"2011","journal-title":"Autophagy J Immunol"},{"key":"ref471","first-page":"185","article-title":"regulates metabolism during effector activation","author":"Hubbard","year":"2010","journal-title":"energy cell J Immunol"},{"key":"ref481","first-page":"13","article-title":"- the tool of cancer cell survival or death","volume":"32","author":"Lamparska","year":"2005","journal-title":"Autophagy"},{"key":"ref191","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.mam.2006.08.002","article-title":"Signalling regulation in disease","volume":"27","author":"Meijer","year":"2006","journal-title":"autophagy health aging Mol Aspects Med"},{"key":"ref451","first-page":"140","article-title":"cytokines","author":"Harris","year":"2011","journal-title":"Autophagy Cytokine"},{"key":"ref621","first-page":"247","article-title":"mechanisms detection","author":"Rudnicka","year":"2011","journal-title":"Apoptosis autophagy methods"},{"key":"ref371","first-page":"85","article-title":"Autophagosome formation during varicella - zoster virus infection following endoplasmic reticulum stress and the unfolded protein response","author":"Carpenter","year":"2011","journal-title":"J Virol"},{"key":"ref81","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1038\/cdd.2011.96","article-title":"Nun ez Molecular definitions of cell death subroutines : recomendations of the Nomenclature Committee on Cell Death","volume":"19","author":"Galluzzi","year":"2012","journal-title":"Cell Death Differ"},{"key":"ref51","first-page":"56","article-title":"autophagy and tumor supression : a novel IFN - \u03b3 induced signaling cascade involving Activated transcriptor factor that collaborates with beta and promotes tumor suppression","author":"Gade","year":"2011","journal-title":"Cytokine"},{"key":"ref201","first-page":"187","article-title":"- mediated dendritic cell activation is essential for innate cytokine production and APC function with respiratory syncytial virus responses","author":"Morris","year":"2011","journal-title":"Autophagy J Immunol"},{"key":"ref151","first-page":"469","article-title":"in inflammation","author":"Levine","year":"2011","journal-title":"Autophagy immunity Nature"},{"key":"ref381","first-page":"240","article-title":"in immunity and cell - autonomous defense against intracellular microbes","author":"Deretic","year":"2011","journal-title":"Autophagy Immunol Rev"},{"key":"ref711","first-page":"22","article-title":"for better or for worse","author":"Wiwaran","year":"2012","journal-title":"Autophagy Cell Res"},{"key":"ref461","doi-asserted-by":"crossref","first-page":"9349","DOI":"10.1158\/0008-5472.CAN-06-1597","article-title":"in cancer good bad or both","author":"Hippert","year":"2006","journal-title":"PS Autophagy Cancer Res"},{"key":"ref251","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1038\/cdd.2011.1","article-title":"TV Dying for a causa mechanisms behind an antimicrobial cell death sodality","volume":"18","author":"Remijsen","year":"2011","journal-title":"Cell Death Differ"},{"key":"ref611","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1038\/cdd.2011.1","article-title":"TV Dying for a causa mechanisms behind an antimicrobial cell death sodality","volume":"18","author":"Remijsen","year":"2011","journal-title":"Cell Death Differ"},{"key":"ref551","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.mam.2006.08.002","article-title":"Signalling regulation in disease","volume":"27","author":"Meijer","year":"2006","journal-title":"autophagy health aging Mol Aspects Med"},{"key":"ref311","first-page":"1","article-title":"as an atypical representative of the Bcl protein family Part a regulator of non - apoptotic programmed cell death","author":"Swoboda","year":"2009"},{"key":"ref281","first-page":"222","article-title":"Role of autophagy in the mammogenesis of bovine mammary glands on the model of mammospheres","author":"Sobolewska","year":"2010","journal-title":"Med Weter"},{"key":"ref531","first-page":"651","article-title":"The origin and evolution of cell death","author":"Maruniewicz","year":"2007"},{"key":"ref231","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.mib.2005.12.007","article-title":"Bacterial evasion of the autophagic defense system","author":"Ogawa","year":"2006","journal-title":"Curr Opin Microbiol"},{"key":"ref581","first-page":"455","article-title":"an important immunological phenomenon","author":"Nied\u017awiedzka","year":"2009","journal-title":"Autophagy"},{"key":"ref391","first-page":"203","article-title":"Cells cleaning their own backyard","author":"Deretic","year":"2008"},{"key":"ref31","first-page":"203","article-title":"Cells cleaning their own backyard","author":"Deretic","year":"2008"},{"key":"ref671","first-page":"1","article-title":"as an atypical representative of the Bcl protein family Part a regulator of non - apoptotic programmed cell death","author":"Swoboda","year":"2009"},{"key":"ref271","first-page":"32","article-title":"The ever - expanding function of NOD viral recognition activation","author":"Kamada","year":"2011","journal-title":"Shaw autophagy cell Trends Immunol"},{"key":"ref521","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1007\/s00018-004-4012-4","article-title":"molecular mechanisms physiological functions and relevance in human pathology","author":"Marin","year":"2004","journal-title":"Autophagy Cell Mol Life Sci"},{"key":"ref261","first-page":"247","article-title":"mechanisms detection","author":"Rudnicka","year":"2011","journal-title":"Apoptosis autophagy methods"},{"key":"ref651","first-page":"88","article-title":"sex steroids regulate autophagy in bovine mammary epithelial cells via the mTOR pathway","author":"Sobolewska","year":"2009","journal-title":"Eur J Cell Biol"},{"key":"ref161","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1007\/s00018-004-4012-4","article-title":"molecular mechanisms physiological functions and relevance in human pathology","author":"Marin","year":"2004","journal-title":"Autophagy Cell Mol Life Sci"},{"key":"ref91","first-page":"140","article-title":"cytokines","author":"Harris","year":"2011","journal-title":"Autophagy Cytokine"},{"key":"ref571","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.1038\/cdd.2012.52","article-title":"The role of autophagy in the pathogenesis of glycogen storage disease type II","volume":"19","author":"Nascimbeni","year":"2012","journal-title":"Cell Death Differ"},{"key":"ref361","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1038\/cdd.2010.157","article-title":"hler in Drosophila ovaries is induced by starvation and is required for oogenesis","volume":"18","author":"Barth","year":"2011","journal-title":"Autophagy Cell Death Differ"},{"key":"ref691","first-page":"150","article-title":"tuberculosis DNA targets bacteria for autophagy by activating the host DNA - sensing pathway","author":"Watson RO","year":"2012","journal-title":"PS Cell"},{"key":"ref411","first-page":"56","article-title":"autophagy and tumor supression : a novel IFN - \u03b3 induced signaling cascade involving Activated transcriptor factor that collaborates with beta and promotes tumor suppression","author":"Gade","year":"2011","journal-title":"Cytokine"},{"key":"ref01","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1038\/cdd.2010.157","article-title":"hler in Drosophila ovaries is induced by starvation and is required for oogenesis","volume":"18","author":"Barth","year":"2011","journal-title":"Autophagy Cell Death Differ"},{"key":"ref661","first-page":"420","article-title":"The types of cell death","author":"St\u0119pie\u0144","year":"2007"},{"key":"ref631","first-page":"32","article-title":"The ever - expanding function of NOD viral recognition activation","author":"Kamada","year":"2011","journal-title":"Shaw autophagy cell Trends Immunol"},{"key":"ref11","first-page":"85","article-title":"Autophagosome formation during varicella - zoster virus infection following endoplasmic reticulum stress and the unfolded protein response","author":"Carpenter","year":"2011","journal-title":"J Virol"},{"key":"ref541","first-page":"351","article-title":"in viral and bacterial infections molecular roulette","author":"Matryniszyn","year":"2008","journal-title":"Autophagy"},{"key":"ref641","first-page":"222","article-title":"Role of autophagy in the mammogenesis of bovine mammary glands on the model of mammospheres","author":"Sobolewska","year":"2010","journal-title":"Med Weter"},{"key":"ref291","first-page":"88","article-title":"sex steroids regulate autophagy in bovine mammary epithelial cells via the mTOR pathway","author":"Sobolewska","year":"2009","journal-title":"Eur J Cell Biol"},{"key":"ref501","first-page":"132","article-title":"in the pathogenesis of disease","author":"Levine","year":"2008","journal-title":"Autophagy Cell"},{"key":"ref21","first-page":"240","article-title":"in immunity and cell - autonomous defense against intracellular microbes","author":"Deretic","year":"2011","journal-title":"Autophagy Immunol Rev"},{"key":"ref71","first-page":"59","article-title":"Role of autophagy in mammary gland development","author":"Gajewska","year":"2008","journal-title":"J Physiol Pharmacol"},{"key":"ref351","first-page":"22","article-title":"for better or for worse","author":"Wiwaran","year":"2012","journal-title":"Autophagy Cell Res"},{"key":"ref421","first-page":"1412","article-title":"in the remodeling of bovine mammary gland biology","author":"Gajewska","year":"2007","journal-title":"Autophagy Med Weter"},{"key":"ref41","first-page":"23","article-title":"Role of autophagy in the host response to microbial infection and potential for therapy","author":"Fabri","year":"2011","journal-title":"Curr Opin Immunol"},{"key":"ref171","first-page":"651","article-title":"The origin and evolution of cell death","author":"Maruniewicz","year":"2007"},{"key":"ref491","first-page":"20","article-title":"antiviral","author":"Lee","year":"2008","journal-title":"Autophagy immunity Curr Opin Immunol"},{"key":"ref681","first-page":"129","article-title":"pathophysiology","author":"Uchiyama","year":"2008","journal-title":"Autophagy physiology Histochem Cell Biol"},{"key":"ref511","first-page":"469","article-title":"in inflammation","author":"Levine","year":"2011","journal-title":"Autophagy immunity Nature"},{"key":"ref431","first-page":"59","article-title":"Role of autophagy in mammary gland development","author":"Gajewska","year":"2008","journal-title":"J Physiol Pharmacol"},{"key":"ref441","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1038\/cdd.2011.96","article-title":"Nun ez Molecular definitions of cell death subroutines : recomendations of the Nomenclature Committee on Cell Death","volume":"19","author":"Galluzzi","year":"2012","journal-title":"Cell Death Differ"},{"key":"ref131","first-page":"20","article-title":"antiviral","author":"Lee","year":"2008","journal-title":"Autophagy immunity Curr Opin Immunol"}],"container-title":["Polish Journal of Veterinary Sciences"],"original-title":[],"link":[{"URL":"http:\/\/content.sciendo.com\/view\/journals\/pjvs\/16\/1\/article-p173.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyter.com\/view\/j\/pjvs.2013.16.issue-1\/pjvs-2013-0026\/pjvs-2013-0026.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,22]],"date-time":"2023-03-22T14:02:59Z","timestamp":1679493779000},"score":1,"resource":{"primary":{"URL":"http:\/\/journals.pan.pl\/dlibra\/publication\/114081\/edition\/99139\/content"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3,1]]},"references-count":72,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.2478\/pjvs-2013-0026","relation":{},"ISSN":["1505-1773"],"issn-type":[{"value":"1505-1773","type":"print"}],"subject":[],"published":{"date-parts":[[2013,3,1]]}}}