{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T22:51:58Z","timestamp":1769986318092,"version":"3.49.0"},"reference-count":68,"publisher":"Polish Academy of Sciences Chancellery","issue":"4","license":[{"start":{"date-parts":[[2013,12,1]],"date-time":"2013-12-01T00:00:00Z","timestamp":1385856000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The effect of Enterococcus faecium CCM7420 (EF) - enterocin-producing and probiotic strain of rabbit origin, Eleutherococcus senticosus extract (ES) and their combination (ES+EF) was determined on selected bacteria in faeces and caecum content, leukocytes phagocytosis, blood biochemistry and growth performance. Ninety-six weaned rabbits were divided into 3 experimental (ES, EF, ES+EF) and control group (CG). The rabbits in the groups ES and EF+ES were fed commercial diet enriched with E. senticosus extract (30 g\/100 kg feed), rabbits in groups EF and CG were fed untreated diet. The rabbits in the EF and ES+EF groups were administered with an overnight culture of E. faecium CCM7420 strain (500 \u03bcl\/animal\/day into water, 109 CFU\/ml). The treatment period lasted 21 days. The microbiological examinations in faecal samples confirmed the presence of E. faecium CCM7420 strain. In groups EF and ES+EF, the reduction of faecal coliforms, Pseudomonas-like sp., Clostridium-like sp. and S. aureus was recorded. Leucocyte phagocytosis significantly increased in all experimental groups (P&lt;0.0001) compared to CG. The lowest GPx values were measured in the ES+EF group. Higher total protein, triglycerides and calcium concentrations were detected in experimental groups compared to CG. The cholesterol concentration decreased in the ES group. The highest average daily gain was recorded in EF group; in ES+EF the better feed conversion ratio and no mortality was recorded. These results indicated that the dietary supplementation with the E. faecium CCM7420 and E. senticosus extract stimulate the leukocytes phagocytosis and reduces the potential pathogens in rabbits digestive tract without oxidative stress and improve the growth performance.<\/jats:p>","DOI":"10.2478\/pjvs-2013-0089","type":"journal-article","created":{"date-parts":[[2014,5,22]],"date-time":"2014-05-22T20:14:07Z","timestamp":1400789647000},"page":"619-627","source":"Crossref","is-referenced-by-count":14,"title":["Combined administration of bacteriocin- -producing, probiotic strain Enterococcus faecium CCM7420 with Eleutherococcus senticosus and their effect in rabbits"],"prefix":"10.24425","volume":"16","author":[{"given":"M. Pog\u00e1ny","family":"Simonov\u00e1","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Laukov\u00e1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Chrastinov\u00e1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Plach\u00e1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Strompfov\u00e1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"\u010cobanov\u00e1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Z.","family":"Formelov\u00e1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Chrenkov\u00e1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"37468","reference":[{"key":"ref391","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1046\/j.1365-2710.2003.00467.x","article-title":"The 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Arzneimittelforsch","author":"Esperester","year":"2001"},{"key":"ref431","first-page":"176","article-title":"Bioactive plants and plant products Effects on animal function welfare","author":"Durmic","year":"2012","journal-title":"health Anim Feed Sci Tech"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/S0723-2020(96)80003-8","article-title":"Pot Characterization of antagonistic activity of Lactobacillus amylovorus and large scale isolation of its bacteriocin amylovorin","volume":"19","author":"De Vuyst","year":"1996","journal-title":"Syst Appl Microbiol"},{"key":"ref681","first-page":"4231","article-title":"ny obanova Effect of combined administration of enterocin sage in rabbits","volume":"14","author":"Szab\u00f3ov\u00e1","year":"2011","journal-title":"Pol J Vet Sci"},{"key":"ref461","first-page":"2315","article-title":"Effect of probiotic treatment in broiler chicks on intestinal macrophage numbers and phagocytosis of Salmonella enteritidis by 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