{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T10:52:42Z","timestamp":1776423162925,"version":"3.51.2"},"reference-count":88,"publisher":"Polish Academy of Sciences Chancellery","issue":"1","license":[{"start":{"date-parts":[[2014,3,1]],"date-time":"2014-03-01T00:00:00Z","timestamp":1393632000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Adenomyosis is defined as the presence of glandular foci beside the endometrium of uterus: in the myometrium and\/or perimetrium depending on the progress of the disorder. So far, adenomyosis has been diagnosed in women and rodents, and studies conducted on cows have been rare. In this review we: (1) summarize the knowledge regarding adenomyosis, (2) compare the symptoms and aetiopathology between women and cows, (3) describe angiogenic uterine processes related to adenomyosis development and (4) outline the influence of adenomyosis on proper fertility processes in cattle (conception and fertility rates).<\/jats:p>","DOI":"10.2478\/pjvs-2014-0028","type":"journal-article","created":{"date-parts":[[2014,9,3]],"date-time":"2014-09-03T15:14:47Z","timestamp":1409757287000},"page":"187-194","source":"Crossref","is-referenced-by-count":11,"title":["Is adenomyosis a problem in reproduction and fertility?"],"prefix":"10.24425","volume":"17","author":[{"given":"A.","family":"Korzekwa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"\u0141upicka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Socha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ch.","family":"Mannelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.J.","family":"Skarzynski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"37468","reference":[{"key":"ref801","first-page":"280","article-title":"The pathophysiology of endometriosis adenomyosis tissue injury repair","author":"Leyendecker","year":"2009","journal-title":"Arch Gynecol Obstet"},{"key":"ref781","first-page":"3","article-title":"An update on adenomyosis Imaging","author":"Levy","year":"2013"},{"key":"ref111","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1093\/molehr\/gat007","article-title":"Gene expression analysis reveals an angiogenic profile in uterine leiomyoma pseudocapsule","volume":"19","author":"Di Tommaso","year":"2013","journal-title":"Mol Hum Reprod"},{"key":"ref741","first-page":"186","article-title":"The aetiology diagnosis and classification of chronic degenerative endometritis In ed Workshop on equine endometritis","volume":"25","author":"Kenney","year":"1992","journal-title":"Equine Vet J"},{"key":"ref841","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1007\/s11259-011-9470-1","article-title":"de EC Differential immunohistochemical expression of matrix metalloproteinase and tissue inhibitor of metalloproteinase in cow uteri with adenomyosis during follicular phase","author":"Moreira","year":"2011","journal-title":"Vet Res Commun"},{"key":"ref121","first-page":"151","article-title":"Mechanism of phytoestrogens action in reproductive processes of mammals and birds","author":"Dusza","year":"2006","journal-title":"Reprod Biol"},{"key":"ref401","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.jri.2011.12.001","article-title":"KP The distribution of immune cells and macrophages in the endometrium of women with recurrent reproductive failure II adenomyosis and macrophages","volume":"93","author":"Tremellen","year":"2012","journal-title":"Russell J Reprod Immunol"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/S0889-8545(21)00148-0","article-title":"current prospectives","volume":"16","author":"Azziz","year":"1989","journal-title":"Obstet Gynecol Clin Am"},{"key":"ref461","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1111\/j.1600-0897.2005.00363.x","article-title":"Increased interleukin messenger RNA expression in macrophage - 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latent cause of infertility Wet","author":"Katkiewicz","year":"2005","journal-title":"Med"},{"key":"ref731","first-page":"1378","article-title":"Adenomyosis of cows uterus - latent cause of infertility Wet","author":"Katkiewicz","year":"2005","journal-title":"Med"},{"key":"ref691","first-page":"71","article-title":"Immunohistochemical and histochemical identification of proteins and carbohydrates in the equine endometrium Expression patterns for mares suffering from endometrosis","author":"Hoffmann","year":"2009","journal-title":"Theriogenology"},{"key":"ref701","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1080\/713773947","article-title":"Endometrial endothelial cells express estrogen and progesterone receptors and exhibit a tissue specific response to angiogenic growth factors","author":"Iruela","year":"1999","journal-title":"Microcirculation"},{"key":"ref881","article-title":"Expression of in the mid - luteal endometrium from women with endometriosis - associated infertility","volume":"11","author":"Szczepa\u0144ska","year":"2012","journal-title":"Reprod Biol"},{"key":"ref61","first-page":"155","article-title":"Biopsy in Holstein Cows Technique histological criteria results","author":"Bonnett","year":"1991","journal-title":"Dairy Can J Vet Res"},{"key":"ref341","first-page":"10387","article-title":"cell - like properties of the endometrial side population : implication in endometrial regeneration One","author":"Masuda","year":"2010"},{"key":"ref561","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1007\/s10397-011-0723-3","article-title":"Is adenomyosis the neglected phenotype of an endomyometrial dysfunction syndrome","author":"Brosens","year":"2012","journal-title":"Gynecol"},{"key":"ref621","first-page":"1","article-title":"den Expression of angiogenic basic fibroblast growth factor platelet derived growth factor thrombospondin and their receptors at the porcine maternal - fetal interface","volume":"9","author":"Edwards","year":"2011","journal-title":"Reprod Biol"},{"key":"ref831","first-page":"10387","article-title":"cell - like properties of the endometrial side population : implication in endometrial regeneration One","author":"Masuda","year":"2010"},{"key":"ref721","first-page":"415","article-title":"Medical treatments for","author":"Kappou","year":"2010","journal-title":"endometriosis Minerva Ginecol"},{"key":"ref251","first-page":"186","article-title":"The aetiology diagnosis and classification of chronic degenerative endometritis In ed Workshop on equine endometritis","volume":"25","author":"Kenney","year":"1992","journal-title":"Equine Vet J"},{"key":"ref971","first-page":"160","article-title":"study in vitro on differentiation of bone marrow mesenchymal stem cells into endometrial epithelial cells in mice","author":"Zhang","year":"2012","journal-title":"Eur Obstet Gynecol Reprod Biol"},{"key":"ref821","first-page":"140","article-title":"Human uterine stem \/ progenitor cells : their possible role in uterine physiology and pathology","author":"Maruyama","year":"2010","journal-title":"Reproduction"},{"key":"ref301","first-page":"1","article-title":"Steroidal regulation of uterine resistance to bacterial infection in livestock","author":"Lewis","year":"2003","journal-title":"Reprod Biol"},{"key":"ref521","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/S0889-8545(21)00148-0","article-title":"current prospectives","volume":"16","author":"Azziz","year":"1989","journal-title":"Obstet Gynecol Clin Am"},{"key":"ref81","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/786132","article-title":"Infertility adenomyosis","author":"Campo","year":"2012","journal-title":"Obstet Gynecol Int"},{"key":"ref891","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.jri.2011.12.001","article-title":"KP The distribution of immune cells and macrophages in the endometrium of women with recurrent reproductive failure II adenomyosis and macrophages","volume":"93","author":"Tremellen","year":"2012","journal-title":"Russell J Reprod Immunol"},{"key":"ref421","first-page":"134","article-title":"Quantitative analysis of changes in endometrial gland morphology during the bovine oestrous cycle and their association with progesterone levels","author":"Wang","year":"2007","journal-title":"Reproduction"},{"key":"ref291","first-page":"3","article-title":"An update on adenomyosis Imaging","author":"Levy","year":"2013"},{"key":"ref531","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.fertnstert.2005.07.1290","article-title":"Short synthetic endostatin peptides inhibit endothelial migration in vitro and endometriosis in a mouse model","volume":"85","author":"Becker","year":"2006","journal-title":"Fertil Steril"},{"key":"ref441","first-page":"235","article-title":"the master of","author":"Wu","year":"2010","journal-title":"endometriosis Exp Biol Med"},{"key":"ref501","first-page":"358","article-title":"Mechanisms of endometrial progesterone resistance","author":"Sabbagh","year":"2012","journal-title":"Mol Cell Endocrinol"},{"key":"ref811","first-page":"1","article-title":"enhances survival and invasiveness of endometrial stromal cells in an autocrine manner by activating akt and mapk erk signal pathway","author":"Li","year":"2012","journal-title":"Fertil Steril"},{"key":"ref271","first-page":"1","article-title":"Induction of \u03b2 and activation of distinct mineralocorticoid receptor - and glucocorticoid receptor - dependent gene networks in decidualizing human endometrial stromal cells","volume":"11","author":"Kuroda","year":"2013","journal-title":"Mol Endocrinol"},{"key":"ref761","first-page":"1","article-title":"Induction of \u03b2 and activation of distinct mineralocorticoid receptor - and glucocorticoid receptor - dependent gene networks in decidualizing human endometrial stromal cells","volume":"11","author":"Kuroda","year":"2013","journal-title":"Mol Endocrinol"},{"key":"ref571","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/786132","article-title":"Infertility adenomyosis","author":"Campo","year":"2012","journal-title":"Obstet Gynecol Int"},{"key":"ref681","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1093\/humrep\/14.3.716","article-title":"IS Changes in vascular basement membrane in the endometrium of Norplant users","volume":"14","author":"Hickey","year":"1999","journal-title":"Hum Reprod"},{"key":"ref141","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1177\/1933719110371854","article-title":"Reciprocal communication between endometrial stromal cells and macrophages","volume":"17","author":"Eyster","year":"2010","journal-title":"Reprod Sci"},{"key":"ref931","first-page":"235","article-title":"the master of","author":"Wu","year":"2010","journal-title":"endometriosis Exp Biol Med"},{"key":"ref91","doi-asserted-by":"crossref","first-page":"1738","DOI":"10.1095\/biolreprod.103.024109","article-title":"of human endometrial epithelial and stromal cells","author":"Chan","year":"2004","journal-title":"Biol Reprod"},{"key":"ref151","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1093\/humupd\/4.4.312","article-title":"Pathophysiology of adenomyosis","author":"Ferenczy","year":"1998","journal-title":"Hum Reprod Update"},{"key":"ref911","first-page":"134","article-title":"Quantitative analysis of changes in endometrial gland morphology during the bovine oestrous cycle and their association with progesterone levels","author":"Wang","year":"2007","journal-title":"Reproduction"},{"key":"ref551","first-page":"155","article-title":"Biopsy in Holstein Cows Technique histological criteria results","author":"Bonnett","year":"1991","journal-title":"Dairy Can J Vet Res"},{"key":"ref311","first-page":"280","article-title":"The pathophysiology of endometriosis adenomyosis tissue injury repair","author":"Leyendecker","year":"2009","journal-title":"Arch Gynecol Obstet"},{"key":"ref371","first-page":"1","article-title":"The expression of vascular endothelial growth factor and its receptors flt fms flk KDR flt and vascular endothelial growth inhibitor in the bovine uterus during the sexual cycle and their correlation with serum sex steroids","author":"Sagsoz","year":"2011","journal-title":"Theriogenology"},{"key":"ref791","first-page":"1","article-title":"Steroidal regulation of uterine resistance to bacterial infection in livestock","author":"Lewis","year":"2003","journal-title":"Reprod Biol"},{"key":"ref261","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.theriogenology.2012.09.023","article-title":"Adenomyosis in the bovine uterus : correlation between frequency age \u03b2 - estradiol - progesterone equilibrium","volume":"17","author":"Korzekwa","year":"2013","journal-title":"Theriogenology"},{"key":"ref771","first-page":"95","article-title":"symptoms histology pregnancy terminations","author":"Levgur","year":"2000","journal-title":"Obstet Gynecol"},{"key":"ref101","first-page":"73","article-title":"biopsy a valuable clinical and research tool in bovine reproduction","author":"Chapwanya","year":"2010","journal-title":"Theriogenology"},{"key":"ref941","first-page":"103","article-title":"Effect of estradiol on proliferation and differentiation of side population stem \/ progenitor cells from murine endometrium","author":"Xu","year":"2011","journal-title":"Reprod Biol"},{"key":"ref961","first-page":"45","article-title":"van der Non - fertility in cows : treatment with PGF and investigation of uterine biopsies","author":"Zaayer","year":"1986","journal-title":"Cytobios"},{"key":"ref671","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1095\/biolreprod65.5.1311","article-title":"of Uterine Glands","author":"Gray","year":"2001","journal-title":"Developmental Biology Biol Reprod"},{"key":"ref11","first-page":"358","article-title":"Mechanisms of endometrial progesterone resistance","author":"Sabbagh","year":"2012","journal-title":"Mol Cell Endocrinol"},{"key":"ref331","first-page":"140","article-title":"Human uterine stem \/ progenitor cells : their possible role in uterine physiology and pathology","author":"Maruyama","year":"2010","journal-title":"Reproduction"},{"key":"ref391","article-title":"Expression of in the mid - luteal endometrium from women with endometriosis - associated infertility","volume":"11","author":"Szczepa\u0144ska","year":"2012","journal-title":"Reprod Biol"},{"key":"ref281","first-page":"95","article-title":"symptoms histology pregnancy terminations","author":"Levgur","year":"2000","journal-title":"Obstet Gynecol"},{"key":"ref131","first-page":"1","article-title":"den Expression of angiogenic basic fibroblast growth factor platelet derived growth factor thrombospondin and their receptors at the porcine maternal - fetal interface","volume":"9","author":"Edwards","year":"2011","journal-title":"Reprod Biol"},{"key":"ref361","first-page":"360","article-title":"Is adenomyosis an immune disease","author":"Igarashi","year":"1998","journal-title":"Hum Reprod Update"},{"key":"ref641","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1093\/humupd\/4.4.312","article-title":"Pathophysiology of adenomyosis","author":"Ferenczy","year":"1998","journal-title":"Hum Reprod Update"}],"container-title":["Polish Journal of Veterinary Sciences"],"original-title":[],"link":[{"URL":"https:\/\/content.sciendo.com\/view\/journals\/pjvs\/17\/1\/article-p187.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyter.com\/view\/j\/pjvs.2014.17.issue-1\/pjvs-2014-0028\/pjvs-2014-0028.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,22]],"date-time":"2023-03-22T14:03:36Z","timestamp":1679493816000},"score":1,"resource":{"primary":{"URL":"http:\/\/journals.pan.pl\/dlibra\/publication\/114202\/edition\/99256\/content"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3,1]]},"references-count":88,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.2478\/pjvs-2014-0028","relation":{},"ISSN":["2300-2557"],"issn-type":[{"value":"2300-2557","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,3,1]]}}}