{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T00:10:35Z","timestamp":1783901435784,"version":"3.55.0"},"reference-count":25,"publisher":"Walter de Gruyter GmbH","issue":"2-3","license":[{"start":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T00:00:00Z","timestamp":1543622400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:bold>Background:<\/jats:bold>\n                    Protein-energy wasting (PEW) is common in patients with chronic kidney disease (CKD), and is associated with high morbidity and mortality. Malnutrition-Inflammation Score (MIS) has significant correlations with prospective hospitalization and mortality, as well as measures of anemia, inflammation, and nutrition in dialysis patients.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Material and Methods:<\/jats:bold>\n                    The study was conducted on 100 adult patients of CKD selected from K&amp;D clinic PGIMS, Rohtak. All the patients went under detailed socioeconomic, clinical, biochemical and radiological examination. The average of three measurements of body weight, height, triceps skin fold thickness (TST), and mid-arm muscle circumference (MAMC) were measured in all patients. MIS was calculated for all the patients.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:<\/jats:bold>\n                    Out of total 100 patients, 64 were male and 36 were female. Overall, the prevalence of malnutrition was 60%. A total of 42%, 16% and 2% patients had mild, moderate and severe malnutrition respectively. Our study also shows significant association between staging of CKD (3 to 5-D) and MIS. A significant negative correlation was found between MIS and factors such as BMI, eGFR, serum calcium and hemoglobin levels. A significant positive correlation of this score was found with blood urea serum creatinine, serum uric acid, serum potassium and serum phosphate. Multivariate analysis showed significant association between MIS and serum albumin, TIBC, BMI, family income and hs-CRP.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusion:<\/jats:bold>\n                    Assessment of key components of malnutrition and inflammation early in disease course will help to identify high risk subjects in whom modifying these predictors will help in providing active and healthy life for CKD patients.\n                  <\/jats:p>","DOI":"10.2478\/prilozi-2018-0042","type":"journal-article","created":{"date-parts":[[2019,1,9]],"date-time":"2019-01-09T04:03:06Z","timestamp":1547006586000},"page":"51-61","source":"Crossref","is-referenced-by-count":17,"title":["Assessment of Malnutrition Inflammation Score in Different Stages of Chronic Kidney Disease"],"prefix":"10.2478","volume":"39","author":[{"given":"H.K.","family":"Aggarwal","sequence":"first","affiliation":[{"name":"Senior Professor & Head Department of Medicine III and Division of Nephrology Pt. B.D. Sharma University of Health Sciences, Rohtak (Haryana)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepak","family":"Jain","sequence":"additional","affiliation":[{"name":"Associate Professor, Department of Medicine and Division of Nephrology , Pt. B.D. Sharma University of Health Sciences , Rohtak (Haryana)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rahul","family":"Chauda","sequence":"additional","affiliation":[{"name":"Resident, Department of Medicine Pt. B.D. Sharma University of Health Sciences , Rohtak (Haryana)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shailesh","family":"Bhatia","sequence":"additional","affiliation":[{"name":"Resident, Department of Medicine Pt. B.D. Sharma University of Health Sciences , Rohtak (Haryana)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajnish","family":"Sehgal","sequence":"additional","affiliation":[{"name":"Ex Resident, Department of Medicine Pt. B.D. Sharma University of Health Sciences , Rohtak (Haryana)"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2018,12,31]]},"reference":[{"key":"2026071214581839962_j_prilozi-2018-0042_ref_001_w2aab3b7b6b1b6b1ab1ab1Aa","doi-asserted-by":"crossref","unstructured":"1. Coresh J, Astor BC, Greene T, Eknoyan G, Levey AS. Prevalence of chronic kidney disease and decreased kidney function in the adult U.S. population: Third National Health and Nutrition Examination Survey. Am J Kidney Dis 2003; 41: 1\u201312.10.1053\/ajkd.2003.5000712500213","DOI":"10.1053\/ajkd.2003.50007"},{"key":"2026071214581839962_j_prilozi-2018-0042_ref_002_w2aab3b7b6b1b6b1ab1ab2Aa","doi-asserted-by":"crossref","unstructured":"2. Fouque D, Kalantar-Zadeh K, Kopple J, Cano N, Chauveau P, Cuppari L, et al. A proposed nomenclature and diagnostic criteria for protein-energy wasting in acute and chronic kidney disease. Kidney Int 2008; 73: 391\u20138.10.1038\/sj.ki.500258518094682","DOI":"10.1038\/sj.ki.5002585"},{"key":"2026071214581839962_j_prilozi-2018-0042_ref_003_w2aab3b7b6b1b6b1ab1ab3Aa","doi-asserted-by":"crossref","unstructured":"3. Carrero JJ, Stenvinkel P, Cuppari L, Ikizler TA, Kalantar-Zadeh K, Kaysen G, et al. Etiology of the protein-energy wasting syndrome in chronic kidney disease: a consensus statement from the International Society of Renal Nutrition and Metabolism (ISRNM). J RenNutr 2013; 23: 77\u201390.10.1053\/j.jrn.2013.01.00123428357","DOI":"10.1053\/j.jrn.2013.01.001"},{"key":"2026071214581839962_j_prilozi-2018-0042_ref_004_w2aab3b7b6b1b6b1ab1ab4Aa","doi-asserted-by":"crossref","unstructured":"4. Kopple JD. MaCollum award lecture, PEM in maintainence dialysis patients. Am J ClinNutr 1996; 65: 1544\u201357.10.1093\/ajcn\/65.5.1544","DOI":"10.1093\/ajcn\/65.5.1544"},{"key":"2026071214581839962_j_prilozi-2018-0042_ref_005_w2aab3b7b6b1b6b1ab1ab5Aa","unstructured":"5. 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ASAIO J1997; 43: 246\u201350.915250310.1097\/00002480-199743030-00026","DOI":"10.1097\/00002480-199743030-00026"},{"key":"2026071214581839962_j_prilozi-2018-0042_ref_011_w2aab3b7b6b1b6b1ab1ac11Aa","doi-asserted-by":"crossref","unstructured":"11. Singh T, Sharma S, Nagesh S. Socio-economic status scales updated for 2017.Int J Res Med Sci 2017; 5(7): 3264\u20137.10.18203\/2320-6012.ijrms20173029","DOI":"10.18203\/2320-6012.ijrms20173029"},{"key":"2026071214581839962_j_prilozi-2018-0042_ref_012_w2aab3b7b6b1b6b1ab1ac12Aa","unstructured":"12. Gonz\u00e1lez-Ortiz AJ, Arce-Santander CV, Vega-Vega O, Correa-Rotter R, Espinosa-Cuevas Mde L. Assessment of the reliability and consistency of the \u201cmalnutrition inflammation score\u201d (MIS) in Mexican adults with chronic kidney disease for diagnosis of protein-energy wasting syndrome (PEW). Nutr Hosp 2014; 31(3): 1352\u20138."},{"key":"2026071214581839962_j_prilozi-2018-0042_ref_013_w2aab3b7b6b1b6b1ab1ac13Aa","doi-asserted-by":"crossref","unstructured":"13. Kalantar-Zadeh K, Ikizler TA, Block G, Avram MM, Kopple JD. Malnutrition-inflammation complex syndrome in dialysis patients: causes and consequences. Am J Kidney Dis 2003; 42(5): 864\u201381.10.1016\/j.ajkd.2003.07.01614582032","DOI":"10.1016\/j.ajkd.2003.07.016"},{"key":"2026071214581839962_j_prilozi-2018-0042_ref_014_w2aab3b7b6b1b6b1ab1ac14Aa","unstructured":"14. Kir HM, Eraldemir C, Dervisoglu E, Caglayan C, Kalender B. Effects of chronic kidney disease and type of dialysis on serum levels of adiponectin, TNF-alpha and high sensitive C-reactive protein. Clin Lab 2012; 58: 495\u2013500."},{"key":"2026071214581839962_j_prilozi-2018-0042_ref_015_w2aab3b7b6b1b6b1ab1ac15Aa","doi-asserted-by":"crossref","unstructured":"15. Lawson JA, Lazarus R, Kelly JJ. Prevalence and prognostic significance of malnutrition in chronic renal insufficiency. J RenNutr 2001; 11: 16\u201322.10.1016\/S1051-2276(01)85914-8","DOI":"10.1016\/S1051-2276(01)85914-8"},{"key":"2026071214581839962_j_prilozi-2018-0042_ref_016_w2aab3b7b6b1b6b1ab1ac16Aa","doi-asserted-by":"crossref","unstructured":"16. Prakash J, Raja R, Mishra RN, Vohra R, Sharma N, Wani IA, et al. High prevalence of malnutrition and inflammation in undialyzed patients with chronic renal failure in developing countries: A single center experience from eastern India. Renal Failure 2007; 29: 811\u20136.10.1080\/08860220701573491","DOI":"10.1080\/08860220701573491"},{"key":"2026071214581839962_j_prilozi-2018-0042_ref_017_w2aab3b7b6b1b6b1ab1ac17Aa","unstructured":"17. Ebrahimzadehkor B, Dorri A, Gharavi AY. Malnutrition inflammation score in hemodialysis patient. Zahedan J Res Med Sci 2014; 16(8): 25\u20138."},{"key":"2026071214581839962_j_prilozi-2018-0042_ref_018_w2aab3b7b6b1b6b1ab1ac18Aa","doi-asserted-by":"crossref","unstructured":"18. Amparo FC, Kamimura MA, Molnar MZ, Cuppari L, Lindholm B, Amodeo C, et al. Diagnostic validation and prognostic significance of the Malnutrition-Inflammation Score in nondialyzed chronic kidney disease patients. Nephrol Dial Transplant 2015; 30(5): 821\u20138.10.1093\/ndt\/gfu380","DOI":"10.1093\/ndt\/gfu380"},{"key":"2026071214581839962_j_prilozi-2018-0042_ref_019_w2aab3b7b6b1b6b1ab1ac19Aa","doi-asserted-by":"crossref","unstructured":"19. Garg AX, Blake PG, Clark WF,Clase CM, Haynes RB, Moist LM. Association between renal insufficiency and malnutrition in older adults: Results from the NHANES III. Kidney Int 2001; 60(5): 1867\u201374.10.1046\/j.1523-1755.2001.00001.x","DOI":"10.1046\/j.1523-1755.2001.00001.x"},{"key":"2026071214581839962_j_prilozi-2018-0042_ref_020_w2aab3b7b6b1b6b1ab1ac20Aa","doi-asserted-by":"crossref","unstructured":"20. Ho LC, Wang HH, Chiang CK, Hung KY, Wu KD. Malnutrition-inflammation score independently determined cardiovascular and infection risk in peritoneal dialysis patients. Blood Purif 2010; 29(3): 308\u201316.10.1159\/000280641","DOI":"10.1159\/000280641"},{"key":"2026071214581839962_j_prilozi-2018-0042_ref_021_w2aab3b7b6b1b6b1ab1ac21Aa","doi-asserted-by":"crossref","unstructured":"21. Stevinkel P, Alvestrand D. Inflammation in end-stage renal disease: Sources, consequences, and therapy. Semin Dial 2002; 15(5): 329\u201337.10.1046\/j.1525-139X.2002.00083.x","DOI":"10.1046\/j.1525-139X.2002.00083.x"},{"key":"2026071214581839962_j_prilozi-2018-0042_ref_022_w2aab3b7b6b1b6b1ab1ac22Aa","doi-asserted-by":"crossref","unstructured":"22. 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Abigon Press 2003; 182\u20133."},{"key":"2026071214581839962_j_prilozi-2018-0042_ref_025_w2aab3b7b6b1b6b1ab1ac25Aa","doi-asserted-by":"crossref","unstructured":"25. Kanwar M, Hashem M, Rosman H, Kamalakannan D, Cheema A, Ali A, et al. Usefulness of clinical evaluation, troponins, and C-reactive protein in predicting mortality among stable hemodialysis patients. Am J Cardiol 2006; 98: 1283\u20137.10.1016\/j.amjcard.2006.05.06417056347","DOI":"10.1016\/j.amjcard.2006.05.064"}],"container-title":["PRILOZI"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/content.sciendo.com\/view\/journals\/prilozi\/39\/2-3\/article-p51.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/reference-global.com\/pdf\/10.2478\/prilozi-2018-0042","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,12]],"date-time":"2026-07-12T23:55:30Z","timestamp":1783900530000},"score":1,"resource":{"primary":{"URL":"https:\/\/reference-global.com\/article\/10.2478\/prilozi-2018-0042"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12,1]]},"references-count":25,"journal-issue":{"issue":"2-3","published-online":{"date-parts":[[2018,12,31]]},"published-print":{"date-parts":[[2018,12,1]]}},"alternative-id":["10.2478\/prilozi-2018-0042"],"URL":"https:\/\/doi.org\/10.2478\/prilozi-2018-0042","relation":{},"ISSN":["1857-8985","1857-9345"],"issn-type":[{"value":"1857-8985","type":"electronic"},{"value":"1857-9345","type":"print"}],"subject":[],"published":{"date-parts":[[2018,12,1]]}}}