{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T21:53:57Z","timestamp":1790027637085,"version":"4.0.1"},"reference-count":32,"publisher":"Walter de Gruyter GmbH","issue":"1","license":[{"start":{"date-parts":[[2019,1,19]],"date-time":"2019-01-19T00:00:00Z","timestamp":1547856000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,1,19]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_raon-2019-0005_s_005\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Peripheral T-cell lymphoma (PTCL) is an uncommon disease with poor clinical outcomes. Radiological reports on the survival of patients with PTCL are scarce. The purpose of this study is to investigate the prognostic value of CT findings to predict clinical outcomes in fifty-one patients with histologically proven PTCL.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_raon-2019-0005_s_006\">\n                    <jats:title>Patients and methods<\/jats:title>\n                    <jats:p>The clinical data and CT images of all patients were retrospectively reviewed. CT features including number of involvement sites, lesion size, shape, margin, density, peritumoral invasion, intratumoral necrosis, lymph node involvement, and degree of contrast enhancement were evaluated. Univariate and multiple logistic regression analysis were used to determine the association between the clinical outcome and radiologic factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_raon-2019-0005_s_007\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Multiple site involvement, an ill-defined margin with peritumoral invasion, inhomogeneous density, and intratumoral necrosis were found to be associated with poor outcomes in univariate analysis (P &lt; 0.05). An ill-defined margin with peritumoral invasion, was identified as an independent risk sign by further multivariate logistic regression analysis (P &lt; 0.05). The area under the ROC curve of this CT feature was 0.745 (P &lt; 0.05).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_raon-2019-0005_s_008\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>An ill-defined margin with peritumoral invasion was a valuable prognostic factor to predict the worse clinical outcomes in patients with PTCL.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2478\/raon-2019-0005","type":"journal-article","created":{"date-parts":[[2019,1,25]],"date-time":"2019-01-25T04:12:53Z","timestamp":1548389573000},"page":"31-38","source":"Crossref","is-referenced-by-count":6,"title":["CT findings predict survival of patients with peripheral T cell lymphoma: a preliminary study"],"prefix":"10.2478","volume":"53","author":[{"given":"Wenbin","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Radiology , Cancer Hospital , Shantou University Medical College , Guangdong , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sen","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Radiology , Cancer Hospital , Shantou University Medical College , Guangdong , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianbang","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Radiology , Cancer Hospital , Shantou University Medical College , Guangdong , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yangkang","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Radiology , Cancer Hospital , Shantou University Medical College , Guangdong , China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2019,1,19]]},"reference":[{"key":"2026071215023131933_j_raon-2019-0005_ref_001","doi-asserted-by":"crossref","unstructured":"Anderson JR, Armitage JO, Weisenburger DD. 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