{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T02:43:14Z","timestamp":1777776194687,"version":"3.51.4"},"reference-count":14,"publisher":"Walter de Gruyter GmbH","issue":"1","license":[{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Left ventricular noncompaction is a rare structural cardiomyopathy that can occur isolated or in relationship with other conditions, mainly with musculoskeletal diseases or congenital heart defects. The association of left ventricular noncompaction and connective tissue disorders, including systemic lupus erythematosus, was scarcely described in the literature. Reported cases are, more likely, cardiomyopathies mimicking left ventricular noncompaction or transient left ventricular noncompaction with ventricular function improving after appropriate treatment.<\/jats:p>\n                  <jats:p>We present the case of a 23-year-old woman admitted for cardiac evaluation because of ECG abnormalities observed during a routine check-up. Echocardiography showed severe systolic and diastolic dysfunction, diffuse hypokinesis and hypertrabeculation, suggestive of left ventricular non-compaction. Cardiac magnetic resonance imaging confirmed the diagnosis. She later presented with specific clinical and biological parameters and was diagnosed with systemic lupus erythematosus. Corticosteroid and hydroxychloroquine treatment induced general improvement of signs and symptoms, but no recovery of cardiac function.<\/jats:p>","DOI":"10.2478\/rjim-2018-0032","type":"journal-article","created":{"date-parts":[[2018,10,31]],"date-time":"2018-10-31T05:03:55Z","timestamp":1540962235000},"page":"78-82","source":"Crossref","is-referenced-by-count":2,"title":["Left Ventricular noncompaction in a patient with systemic lupus erythematosus"],"prefix":"10.2478","volume":"57","author":[{"given":"Mihaela","family":"Dobranici","sequence":"first","affiliation":[{"name":"\u201cCarol Davila\u201d University of Medicine and Pharmacy , Bucharest , Romania"},{"name":"Cardiology Department, \u201cColentina\u201d Clinical Hospital , Bucharest , Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anamaria","family":"Tocitu","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, \u201cColentina\u201d Clinical Hospital , Bucharest , Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caterina","family":"Delcea","sequence":"additional","affiliation":[{"name":"\u201cCarol Davila\u201d University of Medicine and Pharmacy , Bucharest , Romania"},{"name":"Cardiology Department, \u201cColentina\u201d Clinical Hospital , Bucharest , Romania"},{"name":"CDPC Cardiology Laboratory, \u201cColentina\u201d Clinical Hospital , Bucharest , Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gheorghe-Andrei","family":"Dan","sequence":"additional","affiliation":[{"name":"\u201cCarol Davila\u201d University of Medicine and Pharmacy , Bucharest , Romania"},{"name":"Cardiology Department, \u201cColentina\u201d Clinical Hospital , Bucharest , Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2019,3,28]]},"reference":[{"key":"2026042914160688656_j_rjim-2018-0032_ref_001_w2aab3b7c10b1b6b1ab1ab1Aa","doi-asserted-by":"crossref","unstructured":"1. FINSTERER J, ST\u00d6LLBERGER C, TOWBIN JA. Left ventricular noncompaction cardiomyopathy: cardiac, neuromuscular and genetic factors. Nat Rev Cardiol 2017;14:224-37.10.1038\/nrcardio.2016.207","DOI":"10.1038\/nrcardio.2016.207"},{"key":"2026042914160688656_j_rjim-2018-0032_ref_002_w2aab3b7c10b1b6b1ab1ab2Aa","doi-asserted-by":"crossref","unstructured":"2. ELLIOTT P, ANDERSSON B, ARBUSTINI E, BILINSKA Z, CECCHI F, CHARRON P, et al. Classification of the cardiomyopathies: a position statement from the European society of cardiology working group on myocardial and pericardial diseases. Eur Heart J 2008;29:270-6.10.1093\/eurheartj\/ehm342","DOI":"10.1093\/eurheartj\/ehm342"},{"key":"2026042914160688656_j_rjim-2018-0032_ref_003_w2aab3b7c10b1b6b1ab1ab3Aa","doi-asserted-by":"crossref","unstructured":"3. HUSSEIN A, KARIMIANPOUR A, COLLIER P, KRASUSKI RA. Isolated Noncompaction of the Left Ventricle in Adults. J Am Coll Cardiol 2015;66:578\u201385.10.1016\/j.jacc.2015.06.017","DOI":"10.1016\/j.jacc.2015.06.017"},{"key":"2026042914160688656_j_rjim-2018-0032_ref_004_w2aab3b7c10b1b6b1ab1ab4Aa","doi-asserted-by":"crossref","unstructured":"4. JENNI R, OECHSLIN E, SCHNEIDER J, ATTENHOFER JOST C, KAUFMANN PA. Echocardiographic and pathoanatomical characteristics of isolated left ventricular non-compaction: a step towards classification as a distinct cardiomyopathy. Heart 2001;86:666-71.10.1136\/heart.86.6.666","DOI":"10.1136\/heart.86.6.666"},{"key":"2026042914160688656_j_rjim-2018-0032_ref_005_w2aab3b7c10b1b6b1ab1ab5Aa","doi-asserted-by":"crossref","unstructured":"5. ST\u00d6LLBERGER C, FINSTERER J. Left ventricular hypertrabeculation\/noncompaction. J Am Soc Echocardiogr 2004;17:91-100.10.1016\/S0894-7317(03)00514-5","DOI":"10.1016\/S0894-7317(03)00514-5"},{"key":"2026042914160688656_j_rjim-2018-0032_ref_006_w2aab3b7c10b1b6b1ab1ab6Aa","unstructured":"6. RABELO CF, BATISTELLA F, GODINHO RN, MACHADO TS, VELHO FJP, STAUB HL. Systemic lupus erythematosus and transient left ventricular noncompaction. Acta Reumatol Port 2014;39:274-6."},{"key":"2026042914160688656_j_rjim-2018-0032_ref_007_w2aab3b7c10b1b6b1ab1ab7Aa","doi-asserted-by":"crossref","unstructured":"7. OZKOK A, ACAR G, ELCIOGLU OC, BAKAN A, ATILGAN KG, SASAK G, et al. Cardiomyopathy mimicking left ventricular noncompaction in a patient with lupus nephritis. CEN Case Reports 2012;1:69-72.10.1007\/s13730-012-0015-4541152528509061","DOI":"10.1007\/s13730-012-0015-4"},{"key":"2026042914160688656_j_rjim-2018-0032_ref_008_w2aab3b7c10b1b6b1ab1ab8Aa","doi-asserted-by":"crossref","unstructured":"8. ST\u00d6LLBERGER C, GERECKE B, FINSTERER J, ENGBERDING R. Refinement of echocardiographic criteria for left ventricular noncompaction. Int J Cardiol 2013;165:463-7.10.1016\/j.ijcard.2011.08.84521944384","DOI":"10.1016\/j.ijcard.2011.08.845"},{"key":"2026042914160688656_j_rjim-2018-0032_ref_009_w2aab3b7c10b1b6b1ab1ab9Aa","doi-asserted-by":"crossref","unstructured":"9. LIN K, LLOYD-JONES DM, LI D, LIU Y, YANG J, MARKL M, et al. Imaging of cardiovascular complications in patients with systemic lupus erythematosus. Lupus 2015;24:1126-34.10.1177\/0961203315588577456742726038342","DOI":"10.1177\/0961203315588577"},{"key":"2026042914160688656_j_rjim-2018-0032_ref_010_w2aab3b7c10b1b6b1ab1ac10Aa","doi-asserted-by":"crossref","unstructured":"10. ASHRAFI R, GARG P, MCKAY E, GOSNEY J, CHUAH S, DAVIS G. Aggressive cardiac involvement in systemic lupus erythematosus: a case report and a comprehensive literature review. 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