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The patient was transported to the emergency department (ED) at 5:15 a.m. in a very poor general condition, in a deep coma, with acute respiratory failure, hyperthermia (&gt; 39\u00b0C) and generalized seizures. Laboratory tests showed marked leukocytosis, signs of massive rhabdomyolysis, hepatic failure and beginning of acute renal failure. Despite intensive therapy, the patient died 4 weeks after the poisoning in the course of multi-organ dysfunction syndrome. Chemical and toxicological studies of serum and urine samples collected on the poisoning day at 1:40 p.m. confirmed that amphetamine and MXE had been taken earlier that day. Concentration of amphetamine in the serum (0.06 \u03bcg\/ml) was within the non-toxic range, while MXE (0.32 \u03bcg\/ml) was within the toxic range of concentrations. Amphetamine was also detected in the patient\u2019s hair, which suggested a possibility of its use within the last dozen weeks or so. The serious clinical course of intoxication and co-existence of amphetamine and MXE in the patient\u2019s blood and urine suggest the possibility of adverse interactions between them.<\/jats:p>","DOI":"10.2478\/s13382-014-0290-8","type":"journal-article","created":{"date-parts":[[2014,7,24]],"date-time":"2014-07-24T01:16:53Z","timestamp":1406164613000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Acute methoxetamine and amphetamine poisoning with fatal outcome: A case report"],"prefix":"10.13075","volume":"27","author":[{"given":"Marek","family":"Wiergowski","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacek","family":"Anand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maciej","family":"Krzy\u017canowski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zbigniew","family":"Jankowski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5258","reference":[{"issue":"3","key":"290_CR1","first-page":"317","volume":"25","author":"R Skowronek","year":"2012","unstructured":"Skowronek R, Celi\u0144ski R, Chowaniec C, Skowronek A. 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