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J Dermatol Sci 72, 218\u201324.","DOI":"10.1016\/j.jdermsci.2013.07.003"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2) Kamijima M, Hisanaga N, Wang H, Nakajima T (2007) Occupational trichloroethylene exposure as a cause of idiosyncratic generalized skin disorders and accompanying hepatitis similar to drug hypersensitivities. Int Arch Occup Environ Health 80, 357\u201370.","DOI":"10.1007\/s00420-006-0147-y"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3) Huang H, Kamijima M, Wang H, Li S, Yoshikawa T, Lai G, Huang Z, Liu H, Chen J, Takeuchi Y, Nakajima T, Li L (2006) Human herpesvirus 6 reactivation in trichloroethylene-exposed workers suffering from generalized skin disorders accompanied by hepatic dysfunction. J Occup Health 48, 417\u201323.","DOI":"10.1539\/joh.48.417"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4) Jung HG, Kim HH, Song BG, Kim EJ (2012) Trichloroethylene hypersensitivity syndrome: a disease of fatal outcome. Yonsei Med J 53, 231\u20135.","DOI":"10.3349\/ymj.2012.53.1.231"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5) Phoon WH, Chan MO, Rajan VS, Tan KJ, Thirumoorthy T, Goh CL (1984) Stevens-Johnson syndrome associated with occupational exposure to trichloroethylene. Contact Dermat 10, 270\u20136.","DOI":"10.1111\/j.1600-0536.1984.tb00145.x"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6) Fukuchi T, Takizawa D, Adachi T, Ueno T, Hatanaka T, Shimada Y, Kobayashi H, Kakizaki S, Satou K, Yamada M (2017) A case of drug-induced hypersensitivity syndrome due to trichloroethylene. J Jpn Soc Int Med 106, 598\u2013604 (in Japanese).","DOI":"10.2169\/naika.106.598"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7) Ikeoka T, Saito T, Hosaka Y, Takahara N, Suzuki R, Fukushima T, Sato T, Oshima H, Kuramochi S, Chong T (2009) Drug-induced hypersensitivity syndrome caused by trichloroethylene exposure. J Jpn Soc Int Med 98, 1120\u20133 (in Japanese).","DOI":"10.2169\/naika.98.1120"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8) Watanabe H (2011) Hypersensitivity syndrome due to trichloroethylene exposure: a severe generalized skin reaction resembling drug-induced hypersensitivity syndrome. J Dermatol 38, 229\u201335.","DOI":"10.1111\/j.1346-8138.2010.01155.x"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9) Kamijima M, Wang H, Huang H, Li L, Shibata E, Lin B, Sakai K, Liu H, Tsuchiyama F, Chen J, Okamura A, Huang X, Hisanaga N, Huang Z, Ito Y, Takeuchi Y, Nakajima T (2008) Trichloroethylene causes generalized hypersensitivity skin disorders complicated by hepatitis. J Occup Health 50, 328\u201338.","DOI":"10.1539\/joh.L8013"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10) Japan Society for Occupational Health (2017) Recommendation of Occupational Exposure Limits (2017\u20132018). J Occup Health 59, 436\u201369.","DOI":"10.1539\/joh.ROEL2017"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11) Ikeda M, Imanura T (1973) Biological half-life of trichloroethylene and tetrachloroethylene in human subjects. Int Arch Arbeitsmed 31, 209\u201324.","DOI":"10.1007\/BF00539241"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12) Br\u00fcning T, Bolt HM (2000) Renal toxicity and carcinogenicity of trichloroethylene: key results, mechanisms, and controversies. Crit Rev Toxicol 30, 253\u201385.","DOI":"10.1080\/10408440091159202"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13) Nakajima T (1997) Cytochrome P450 isoforms and the metabolism of volatile hydrocarbons of low relative molecular mass. J Occup Health 39, 83\u201391.","DOI":"10.1539\/joh.39.83"},{"key":"14","unstructured":"14) ACGIH (2015) 2015 TLVs and BEIs \u2212 Threshold limit values for chemical substances and physical agents &amp; biological exposure indices with 7th edition documentation, ACGIH, Cincinnati."},{"key":"15","unstructured":"15) Ministry of Health of the People\u2019s Republic of China (2007) Diagnostic criteria of occupational medicamentose-like dermatitis due to trichloroethylene. National Occupational Health Standard GBZ 185\u20132006 of P.R. of China (in Chinese)."},{"key":"16","doi-asserted-by":"crossref","unstructured":"16) Ikeda M (1977) Metabolism of trichloroethylene and tetrachloroethylene in human subjects. Environ Health Perspect 21, 239\u201345.","DOI":"10.1289\/ehp.7721239"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17) Ohara A, Michitsuji H, Jyoyama Y, Yamaguchi K, Fujiki Y (1991) Determination of trichloroacetic acid and trichloroethanol by head-space gas chromatography (HS.GC). Sangyo Igaku 33, 94\u2013103 (in Japanese).","DOI":"10.1539\/joh1959.33.94"},{"key":"18","unstructured":"18) U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER), Center for Biologics Evaluation and Research (CBER) (1999) Guidance for Industry\u2212population pharmacokinetics. https:\/\/www.fda.gov\/downloads\/drugs\/guidances\/UCM072137.pdf. Accessed February 13, 2018."},{"key":"19","doi-asserted-by":"crossref","unstructured":"19) Inoue O, Seiji K, Kawai T, Jin C, Liu YT, Chen Z, Cai SX, Yin SN, Li GL, Nakatsuka H, Watanabe T, Ikeda M (1989) Relationship between vapor exposure and urinary metabolite excretion among workers exposed to trichloroethylene. Am J Ind Med 15, 103\u201310.","DOI":"10.1002\/ajim.4700150111"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20) Okino T, Nakajima T, Nakano M (1991) Morphological and biochemical analyses of trichloroethylene hepatotoxicity: differences in ethanol- and phenobarbital-pretreated rats. Toxicol Appl Pharmacol 108, 379\u201389.","DOI":"10.1016\/0041-008X(91)90084-R"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21) Fisher JW (2000) Physiologically based pharmacokinetic models for trichloroethylene and its oxidative metabolites. Environ Health Perspect 108 Suppl 2, 265\u201373.","DOI":"10.1289\/ehp.00108s2265"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22) Hibino Y, Wang H, Naito H, Zhao N, Wang D, Jia X, Li H, Song X, Liu L, Huang Y, Ito Y, Huang H, Kamijima M, Nakajima T (2013) Sex differences in metabolism of trichloroethylene and trichloroethanol in guinea pigs. J Occup Health 55, 443\u20139.","DOI":"10.1539\/joh.13-0091-OA"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23) Li H, Dai Y, Huang H, Li L, Leng S, Cheng J, Niu Y, Duan H, Liu Q, Zhang X, Huang X, Xie J, Feng Z, Wang J, He J, Zheng Y (2007) HLA-B*1301 as a biomarker for genetic susceptibility to hypersensitivity dermatitis induced by trichloroethylene among workers in China. 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