{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T04:03:07Z","timestamp":1751515387454,"version":"3.41.0"},"reference-count":21,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,26]],"date-time":"2025-06-26T00:00:00Z","timestamp":1750896000000},"content-version":"vor","delay-in-days":176,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Revista de Investigaci\u00f3n Cl\u00ednica"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.24875\/ric.24000189","type":"journal-article","created":{"date-parts":[[2025,1,14]],"date-time":"2025-01-14T23:12:47Z","timestamp":1736896367000},"page":"6-12","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Mir-155 as a Potential Biomarker for Disease Severity in St-Segment Elevation myocardial Infarction: Insights from a university-Affiliated Cardiovascular Center"],"prefix":"10.1016","volume":"77","author":[{"given":"Ailyn","family":"Morales-Renter\u00eda","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amina","family":"Ruiz-Santos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis M.","family":"Amezcua-Castillo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jazm\u00edn A.","family":"Guerra-L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kietse\u00e9 A.","family":"D\u00edaz-Dom\u00ednguez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 L","family":"S\u00e1nchez-Gloria","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H\u00e9ctor","family":"Gonz\u00e1lez-Pacheco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis M.","family":"Amezcua-Guerra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.24875\/RIC.24000189_bib1","doi-asserted-by":"crossref","DOI":"10.3390\/biomedicines11092422","article-title":"Diagnostic performance of serum MicroRNAs for ST-segment elevation myocardial infarction in the emergency department","volume":"11","author":"Amezcua-Guerra","year":"2023","journal-title":"Biomedicines"},{"key":"10.24875\/RIC.24000189_bib2","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22094799","article-title":"MicroRNAs in acute ST elevation myocardial infarction-a new tool for diagnosis and prognosis: therapeutic implications","volume":"22","author":"Sc\u0103rl\u0103tescu","year":"2021","journal-title":"Int J Mol Sci"},{"key":"10.24875\/RIC.24000189_bib3","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1161\/CIRCULATIONAHA.117.029870","article-title":"Acute coronary syndromes: the way forward from mechanisms to precision treatment","volume":"136","author":"Crea","year":"2017","journal-title":"Circulation"},{"key":"10.24875\/RIC.24000189_bib4","doi-asserted-by":"crossref","DOI":"10.3390\/biomedicines11092444","article-title":"C-reactive protein: the quintessential marker of systemic inflammation in coronary artery disease-advancing toward precision medicine","volume":"11","author":"Amezcua-Castillo","year":"2023","journal-title":"Biomedicines"},{"key":"10.24875\/RIC.24000189_bib5","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.jjcc.2018.11.010","article-title":"Derivation and validation of a simple inflammation-based risk score system for predicting in-hospital mortality in acute coronary syndrome patients","volume":"73","author":"Gonz\u00e1lez-Pacheco","year":"2019","journal-title":"J Cardiol"},{"key":"10.24875\/RIC.24000189_bib6","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/j.jacc.2005.04.051","article-title":"Race and gender differences in C-reactive protein levels","volume":"46","author":"Khera","year":"2005","journal-title":"J Am Coll Cardiol"},{"key":"10.24875\/RIC.24000189_bib7","first-page":"191","article-title":"Prote\u00edna C reactiva, aspectos cardiovasculares de una prote\u00edna de fase aguda: una actualizaci\u00f3n para el m\u00e9dico","volume":"94","author":"S\u00e1enz-San Mart\u00edn","year":"2024","journal-title":"Arch Cardiol Mex"},{"key":"10.24875\/RIC.24000189_bib8","doi-asserted-by":"crossref","DOI":"10.3390\/ijms23137167","article-title":"MicroRNA-based diagnosis and therapy","volume":"23","author":"Ho","year":"2022","journal-title":"Int J Mol Sci"},{"key":"10.24875\/RIC.24000189_bib9","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/7437281","article-title":"miR-155: an important role in inflammation response","volume":"2022","author":"Hu","year":"2022","journal-title":"J Immunol Res"},{"key":"10.24875\/RIC.24000189_bib10","doi-asserted-by":"crossref","first-page":"325","DOI":"10.21037\/cdt-21-743","article-title":"MicroRNA-155 inhibition attenuates myocardial infarction-induced connexin 43 degradation in cardiomyocytes by reducing pro-inflammatory macrophage activation","volume":"12","author":"Yang","year":"2022","journal-title":"Cardiovasc Diagn Ther"},{"key":"10.24875\/RIC.24000189_bib11","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1161\/CIRCRESAHA.109.215566","article-title":"Circulating microRNAs in patients with coronary artery disease","volume":"107","author":"Fichtlscherer","year":"2010","journal-title":"Circ Res"},{"key":"10.24875\/RIC.24000189_bib12","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1038\/s41423-019-0303-4","article-title":"MicroRNA-155 expression suggests a sex disparity in innate lymphoid cells at the single-cell level","volume":"17","author":"Malmh\u00e4ll","year":"2020","journal-title":"Cell Mol Immunol"},{"key":"10.24875\/RIC.24000189_bib13","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1038\/cmi.2011.22","article-title":"The altered expression of inflammation-related microRNAs with microRNA-155 expression correlates with Th17 differentiation in patients with acute coronary syndrome","volume":"8","author":"Yao","year":"2011","journal-title":"Cell Mol Immunol"},{"key":"10.24875\/RIC.24000189_bib14","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1155\/2011\/247654","article-title":"MicroRNAs, innate immunity and ventricular rupture in human myocardial infarction","volume":"31","author":"Zidar","year":"2011","journal-title":"Dis Markers"},{"key":"10.24875\/RIC.24000189_bib15","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1002\/eji.200939381","article-title":"Micro-RNA-155 inhibits IFN-gamma signaling in CD4+ T cells","volume":"40","author":"Banerjee","year":"2010","journal-title":"Eur J Immunol"},{"key":"10.24875\/RIC.24000189_bib16","doi-asserted-by":"crossref","first-page":"961","DOI":"10.2310\/JIM.0b013e3181ff46d7","article-title":"MicroRNA-155 silencing enhances inflammatory response and lipid uptake in oxidized low-density lipoprotein-stimulated human THP-1 macrophages","volume":"58","author":"Huang","year":"2010","journal-title":"J Investig Med"},{"key":"10.24875\/RIC.24000189_bib17","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1111\/imm.12468","article-title":"Physiological roles of miR-155","volume":"145","author":"Mashima","year":"2015","journal-title":"Immunology"},{"key":"10.24875\/RIC.24000189_bib18","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1161\/ATVBAHA.113.302701","article-title":"MicroR-NA-155 deficiency results in decreased macrophage inflammation and attenuated atherogenesis in apolipoprotein E-deficient mice","volume":"34","author":"Du","year":"2014","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.24875\/RIC.24000189_bib19","doi-asserted-by":"crossref","DOI":"10.1126\/scisignal.2000610","article-title":"Delivery of microRNA-126 by apoptotic bodies induces CXCL12-dependent vascular protection","volume":"2","author":"Zernecke","year":"2009","journal-title":"Sci Signal"},{"key":"10.24875\/RIC.24000189_bib20","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-023-45146-8","article-title":"Peripheral blood mononuclear cells expression of miR-200c, miR-125b, miR-27b, miR-203, and miR-155 in patients with significant or insignificant coronary artery stenosis","volume":"13","author":"Saadatian","year":"2023","journal-title":"Sci Rep"},{"key":"10.24875\/RIC.24000189_bib21","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/4579806","article-title":"MicroRNA-155 promotes myocardial infarction-induced apoptosis by targeting RNA-binding protein QKI","author":"Guo","year":"2019","journal-title":"Oxid Med Cell Longev"}],"container-title":["Revista de Investigaci\u00f3n Cl\u00ednica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0034837625001949?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0034837625001949?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.clinicalandtranslationalinvestigation.com\/frame_esp.php?id=521","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T06:10:30Z","timestamp":1751436630000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0034837625001949"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["S0034837625001949"],"URL":"https:\/\/doi.org\/10.24875\/ric.24000189","relation":{},"ISSN":["0034-8376"],"issn-type":[{"type":"print","value":"0034-8376"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mir-155 as a Potential Biomarker for Disease Severity in St-Segment Elevation myocardial Infarction: Insights from a university-Affiliated Cardiovascular Center","name":"articletitle","label":"Article Title"},{"value":"Revista de Investigaci\u00f3n Cl\u00ednica","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.24875\/RIC.24000189","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2025 Revista de Investigaci\u00f3n Cl\u00ednica. Published by Permanyer. Published by Elsevier Espa\u00f1a, S.L.U.","name":"copyright","label":"Copyright"}]}}