{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:55:58Z","timestamp":1787025358845,"version":"build-2736575974"},"reference-count":36,"publisher":"Oceanside Publications Inc.","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["allergy asthma proc"],"published-print":{"date-parts":[[2020,11,1]]},"abstract":"\n Background:<\/jats:bold>\n It is widely acknowledged that food sensitization is related to atopic dermatitis in infants and young children.\n Objective:<\/jats:bold>\n To investigate the association of aeroallergen sensitization with increased rates and severity of atopic dermatitis\n in school children.\n Methods:<\/jats:bold>\n We enrolled 576 children (mean age, 9.4 \u00b1 1.8 years) from six elementary schools. Atopic dermatitis was diagnosed by questionnaires, and severity was rated by physical examinations graded by using the Scoring Atopic Dermatitis (SCORAD)\n index. Skin-prick tests to 22 common allergens (6 aeroallergens and 16 food allergens) were conducted. Logistic and linear regression analyses were performed by using two models: model I adjusted for age, sex, and body mass index z score; and model II adjusted for all model I factors plus\n asthma and allergic rhinitis.\n Results:<\/jats:bold>\n We diagnosed atopic dermatitis in 22.4% (n = 129) of the children, sensitization to foods in 48.3% (n = 278), and sensitization to aeroallergens in 11.3% (n = 65). A total of 26.2% of the children (n = 149) had mild and 6.5% had moderate-to-severe\n symptoms and signs of atopic dermatitis (n = 37). Atopic dermatitis was associated with sensitization to aeroallergens and eosinophilia (model I), but this risk was no longer significant after additional adjustment for current allergic status (model II). However, the relationship of the total\n SCORAD score with aeroallergen sensitization and eosinophilia was significant in model I and model II.\n Conclusion:<\/jats:bold>\n The severity of atopic dermatitis correlated with the extent of allergic sensitization and eosinophilia. Analysis of our results suggests that more sensitization\n to dust mites and eosinophilia are related to increased rates and high severity scores of atopic dermatitis.\n <\/jats:p>","DOI":"10.2500\/aap.2020.41.200067","type":"journal-article","created":{"date-parts":[[2020,10,28]],"date-time":"2020-10-28T01:00:37Z","timestamp":1603846837000},"page":"428-435","source":"Crossref","is-referenced-by-count":20,"title":["Atopic dermatitis: Correlation of severity with allergic sensitization and eosinophilia"],"prefix":"10.2500","volume":"41","author":[{"given":"Eun Kyo","family":"Ha","sequence":"first","affiliation":[{"name":"From the Department of Pediatrics, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ju Hee","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Korea;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung Won","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Data Science, Sejong University College of Software Convergence, Seoul, Korea;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hye Mi","family":"Jee","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Korea;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youn Ho","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, CHA Gangnam Medical Center, CHA University School of Medicine, Seoul, Korea; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hey Sung","family":"Baek","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Man Yong","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Korea;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1355","reference":[{"key":"B1","doi-asserted-by":"crossref","first-page":"278","DOI":"10.3345\/cep.2019.01291","article-title":"Ten-year trends and prevalence of asthma, allergic rhinitis, and atopic dermatitis among the Korean population, 2008-2017","volume":"63","author":"Ha","year":"2020","journal-title":"Clin Exp Pediatr"},{"key":"B2","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1067\/mpd.2000.108207","article-title":"The association of atopic dermatitis in infancy with immunoglobulin E food sensitization","volume":"137","author":"Hill","year":"2000","journal-title":"J 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