{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,5]],"date-time":"2025-05-05T20:29:19Z","timestamp":1746476959393},"reference-count":25,"publisher":"Oceanside Publications Inc.","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["allergy asthma proc"],"published-print":{"date-parts":[[2022,7,1]]},"abstract":"<jats:p>It has been more than a decade since the most recent allergen immunotherapy (AIT) practice parameter was published and 5 years since a focused practice parameter on sublingual immunotherapy (SLIT) was issued. There is an unmet need, therefore, for a more up-to-date, concise summary of AIT to be published to provide allergy\/immunology practitioners, allergy\/immunology fellows-in-training, medical students, residents, and other health-care practitioners with the most current information available on AIT. The Allergen Immunotherapy Primer (AITP) is not intended to define a standard of care or to be inclusive of all proper methods of care, nor is it intended to replace or supplant established AIT practice parameters; rather, the goal of this AITP is to supplement the established practice parameters and to serve primarily as an updated tool for the practicing allergist\/immunologist, allergy\/immunology trainees, and health-care professionals seeking practical and concise information with regard to AIT. Primer topics include the history of AIT; descriptions of the mechanisms and biomarkers of subcutaneous immunotherapy (SCIT) and SLIT; the efficacy and safety of SCIT; the efficacy and safety of SLIT, pediatric SLIT, and SCIT; the long-term efficacy of SLIT and SCIT; long-term adherence strategies for AIT; the implications of real-world data for AIT; the role of AIT for asthma; patterns of cross-allergenicity among pollens; a practical implementation guide for optimized construction of AIT vaccines; standardization of allergen extracts; updated information on federal regulations about the United States Pharmacopeia and the compounding of allergenic extracts; an update on AIT venom immunotherapy; the advantages and disadvantages of accelerated immunotherapy regimens; the important role of shared decision-making in AIT and how it can be incorporated into the informed consent process; and a forecast of future directions in allergen immunotherapy.<\/jats:p>","DOI":"10.2500\/aap.2022.43.220039","type":"journal-article","created":{"date-parts":[[2022,7,12]],"date-time":"2022-07-12T04:31:26Z","timestamp":1657600286000},"page":"245-247","source":"Crossref","is-referenced-by-count":5,"title":["Essentials of allergen immunotherapy: A primer for the practitioner"],"prefix":"10.2500","volume":"43","author":[{"given":"Joseph A.","family":"Bellanti","sequence":"first","affiliation":[{"name":"From the Department of Pediatrics and Microbiology-Immunology;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Russell A.","family":"Settipane","sequence":"additional","affiliation":[{"name":"Department of Medicine at the Alpert Medical School, Brown University, Providence, Rhode Island;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lawrence","family":"DuBuske","sequence":"additional","affiliation":[{"name":"George Washington University Hospital, Washington, D.C.; 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