{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T05:15:23Z","timestamp":1675228523307},"reference-count":15,"publisher":"Oceanside Publications Inc.","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["allergy asthma proc"],"published-print":{"date-parts":[[2022,11,1]]},"abstract":"Background:<\/jats:bold> Curcumin has been shown to decrease allergic symptoms and biomarkers in some animal and human studies. Objective:<\/jats:bold> Our study aimed to determine if curcumin affects immediate skin-prick testing. Methods:<\/jats:bold> We enrolled 34 participants\n sensitized to select antigens. The participants were randomized to treatment with curcumin or placebo in a double-blind fashion. The participants underwent titrated skin-prick testing before and after 1 week of treatment, and the pre- and posttreatment skin test wheals and flares were compared.\n Results:<\/jats:bold> Curcumin did not have a statistically significant effect on immediate skin-prick test wheal or flare size. Conclusion:<\/jats:bold> Although curcumin may attenuate allergic symptoms and biomarkers, it does not have a significant effect on immediate skin-prick\n test results and does not need to be discontinued before testing.<\/jats:p>","DOI":"10.2500\/aap.2022.43.220067","type":"journal-article","created":{"date-parts":[[2022,11,6]],"date-time":"2022-11-06T04:30:51Z","timestamp":1667709051000},"page":"543-545","source":"Crossref","is-referenced-by-count":1,"title":["Curcumin does not significantly affect immediate skin tests"],"prefix":"10.2500","volume":"43","author":[{"given":"Lara M.","family":"Gross","sequence":"first","affiliation":[{"name":"From the Division of Allergy and Clinical Immunology, Dallas Allergy and Asthma Center;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harold S.","family":"Nelson","sequence":"additional","affiliation":[{"name":"Division of Allergy and Clinical Immunology, Department of Medicine, National Jewish Health, Denver, Colorado; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aastha","family":"Khatiwada","sequence":"additional","affiliation":[{"name":"Division of Biostatistics and Bioinformatics, National Jewish Health, Denver, Colorado"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Flavia C.L.","family":"Hoyte","sequence":"additional","affiliation":[{"name":"Division of Allergy and Clinical Immunology, Department of Medicine, National Jewish Health, Denver, Colorado; and"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1355","reference":[{"key":"B1","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1002\/mnfr.200700293","article-title":"Immunomodulatory effects of curcumin in allergy","volume":"52","author":"Kurup","year":"2008","journal-title":"Mol Nutr Food Res"},{"key":"B2","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.cellimm.2015.09.010","article-title":"Anti-inflammatory effect of curcumin on mast cell-mediated allergic 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