{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T12:40:35Z","timestamp":1778503235566,"version":"3.51.4"},"reference-count":18,"publisher":"Oceanside Publications Inc.","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["allergy asthma proc"],"published-print":{"date-parts":[[2023,9,1]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> The coronavirus disease 2019 (COVID-19) pandemic posed restrictions to many standard practices. Dysphagia is a common presentation of eosinophilic esophagitis (EoE) in adults, and biopsy via esophagogastroduodenoscopy (EGD) is required for diagnosis. We hypothesized\n that a diagnosis of EoE has declined during the pandemic.  <jats:bold>Objective:<\/jats:bold> To investigate whether the COVID-19 pandemic influenced the likelihood of an EGD and an EoE diagnosis in patients with dysphagia.  <jats:bold>Methods:<\/jats:bold> In this retrospective matched cohort study,\n we used the TriNetX US Collaborative Network to identify adult patients who presented with dysphagia to the emergency department (ED) during the year of and the year preceding the pandemic. Patients with a previous EoE diagnosis were excluded. The two cohorts were balanced for demographics,\n gastroesophageal reflux disease (GERD) diagnosis, obesity, H<jats:sub>2<\/jats:sub> blockers and proton-pump inhibitors use, anemia, smoking, and alcohol use. The proportion of patients who received an EGD, and an EoE and a GERD diagnosis were contrasted up to 90 days from ED evaluation.  <jats:bold>Results:<\/jats:bold>\n We identified 16,942 adult patients during the pandemic, and 16,942 adult patients the year preceding the pandemic who presented to the ED with a concern of dysphagia. During the 30-day follow-up period, no significant difference was observed in the proportion of patients who received\n an EGD during the pandemic versus the prepandemic period at 1, 7, and 30 days from ED evaluation. The proportion of patients who received an EoE diagnosis was not different, but slightly more patients received a GERD diagnosis during the pandemic versus prepandemic that was evident by day\n 30 (31.2% versus 30%; p\u2009\u2264\u20090.05).  <jats:bold>Conclusion:<\/jats:bold> Our results revealed that the COVID-19 pandemic did not significantly impact diagnostic EGD and an EoE diagnosis.<\/jats:p>","DOI":"10.2500\/aap.2023.44.230031","type":"journal-article","created":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T07:34:46Z","timestamp":1693985686000},"page":"333-339","source":"Crossref","is-referenced-by-count":3,"title":["Diagnosis of eosinophilic esophagitis in patients with dysphagia during the Coronavirus Disease 2019 (COVID-19) pandemic"],"prefix":"10.2500","volume":"44","author":[{"given":"Jennifer","family":"Brennan","sequence":"first","affiliation":[{"name":"From the Division of Pulmonary, Allergy and Critical Care, Department of Medicine, Pennsylvania State University, Hershey, Pennsylvania, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kelsey","family":"Yamada","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Pennsylvania State University, Hershey, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taha","family":"Al-Shaikhly","sequence":"additional","affiliation":[{"name":"From the Division of Pulmonary, Allergy and Critical Care, Department of Medicine, Pennsylvania State University, Hershey, Pennsylvania, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gisoo","family":"Ghaffari","sequence":"additional","affiliation":[{"name":"From the Division of Pulmonary, Allergy and Critical Care, Department of Medicine, Pennsylvania State University, Hershey, Pennsylvania, and"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1355","reference":[{"key":"B1","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1001\/jama.2021.14920","article-title":"Eosinophilic esophagitis: a review","volume":"326","author":"Muir","year":"2021","journal-title":"JAMA"},{"key":"B2","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.anai.2019.12.004","article-title":"EoE disease monitoring: where we are and where we are going","volume":"124","author":"Godwin","year":"2020","journal-title":"Ann Allergy Asthma Immunol"},{"key":"B3","doi-asserted-by":"crossref","first-page":"178","DOI":"10.2500\/aap.2022.43.220014","article-title":"Current and emerging therapies for eosinophilic esophagitis","volume":"43","author":"Sher","year":"2022","journal-title":"Allergy Asthma Proc"},{"key":"B4","doi-asserted-by":"crossref","first-page":"78","DOI":"10.2500\/aap.2022.43.210102","article-title":"Outcomes of eosinophilic esophagitis in patients managed in a multidisciplinary clinic","volume":"43","author":"McMurray","year":"2022","journal-title":"Allergy Asthma Proc"},{"key":"B5","volume-title":"National Survey Trends in Telehealth Use in 2021: Disparities in Utilization and Audio vs. Video Services","author":"Karimi","year":"2022"},{"key":"B6","doi-asserted-by":"crossref","first-page":"e2138038","DOI":"10.1001\/jamanetworkopen.2021.38038","article-title":"Trends in US surgical procedures and health care system response to policies curtailing elective surgical operations during the COVID-19 pandemic","volume":"4","author":"Mattingly","year":"2021","journal-title":"JAMA Netw Open"},{"key":"B7","doi-asserted-by":"crossref","first-page":"2612","DOI":"10.1111\/ajt.16239","article-title":"Potential indirect effects of the COVID-19 pandemic on use of emergency departments for acute life-threatening conditions - 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