{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T19:38:12Z","timestamp":1768073892709,"version":"3.49.0"},"reference-count":19,"publisher":"Oceanside Publications Inc.","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["allergy asthma proc"],"published-print":{"date-parts":[[2024,7,1]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> There is controversy on whether allergic contact dermatitis (ACD) is associated with atopy. Research on eczema and the risk of ACD is mixed, and there is sparse literature on other atopic conditions.  <jats:bold>Objective:<\/jats:bold> Our study examined the prevalence\n of several atopic conditions, including allergic rhinitis, eczema, asthma, and food allergies in patients with ACD, and compared these to patients without ACD.  <jats:bold>Methods:<\/jats:bold> We retrospectively reviewed adult patients ages \u2265 18 years with ACD (n = 162) with positive patch\n testing results and documented any history of atopy, including childhood eczema, asthma, allergic rhinitis, and immunoglobulin E\u2010mediated food allergy. The prevalence of atopic conditions was compared between our ACD cohort and controls without ACD (n = 163) from our electronic medical\n records system (age and gender matched).  <jats:bold>Results:<\/jats:bold> Among our patients with ACD, 53 (33%) had allergic rhinitis, 22 (14%) had childhood eczema, 32 (20%) had asthma, and 8 (5%) had food allergies. We observed that the odds of atopy overall (n = 76) in the ACD group compared\n with the control group were increased (odds ratio [OR] 1.88; p\u2009=\u20090.007). Allergic rhinitis was the highest risk factor (n = 53) with an OR of 12.64 (p\u2009&lt;\u20090.001). Childhood eczema (n = 22) was also increased in the ACD group (OR 2.4; p\u2009=\u20090.026). The\n odds of asthma and food allergy in the ACD group were also increased; however, the difference was not statistically significant from the control group (OR 1.76 [p\u2009=\u20090.071] and OR 2.76 [p\u2009=\u20090.139], respectively).  <jats:bold>Conclusion:<\/jats:bold> Patients with ACD\n had increased odds of eczema, allergic rhinitis, and atopic conditions overall. Asthma and food allergies were not found to have a statistically significant correlation. Larger studies that delve into atopic risk factors in ACD would be important to confirm these findings.<\/jats:p>","DOI":"10.2500\/aap.2024.45.240019","type":"journal-article","created":{"date-parts":[[2024,7,10]],"date-time":"2024-07-10T04:33:48Z","timestamp":1720586028000},"page":"262-267","source":"Crossref","is-referenced-by-count":2,"title":["Evaluation of atopic diseases in patients with allergic contact dermatitis"],"prefix":"10.2500","volume":"45","author":[{"given":"Ashley","family":"Sandoval","sequence":"first","affiliation":[{"name":"From the Division of Basic and Clinical Immunology, Department of Medicine, University of California Irvine, Orange, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yela","family":"Jung","sequence":"additional","affiliation":[{"name":"From the Division of Basic and Clinical Immunology, Department of Medicine, University of California Irvine, Orange, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iris","family":"Kim","sequence":"additional","affiliation":[{"name":"From the Division of Basic and Clinical Immunology, Department of Medicine, University of California Irvine, Orange, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nina","family":"Sadigh","sequence":"additional","affiliation":[{"name":"Department of Allergy, Asthma, and Clinical Immunology, Kaiser Permanente Los Angeles Medical Center, Los Angeles, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jimmy","family":"Kwon","sequence":"additional","affiliation":[{"name":"Department of Statistics, University of California Irvine, Irvine, California, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yesim Yilmaz","family":"Demirdag","sequence":"additional","affiliation":[{"name":"From the Division of Basic and Clinical Immunology, Department of Medicine, University of California Irvine, Orange, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asal Gharib","family":"Naderi","sequence":"additional","affiliation":[{"name":"Division of Geriatric, Hospital, Palliative and General Internal Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tiffany","family":"Jean","sequence":"additional","affiliation":[{"name":"Department of Allergy, Asthma, and Clinical Immunology, Kaiser Permanente Los Angeles Medical Center, Los Angeles, California"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1355","reference":[{"key":"B1","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.anai.2020.10.003","article-title":"A review of contact dermatitis","volume":"126","author":"Brar","year":"2021","journal-title":"Ann Allergy Asthma Immunol"},{"key":"B2","doi-asserted-by":"crossref","first-page":"861053","DOI":"10.3389\/fcimb.2022.861053","article-title":"Global burden, incidence and disability-adjusted life-years for dermatitis: a systematic analysis combined with socioeconomic development status, 1990-2019","volume":"12","author":"Xue","year":"2022","journal-title":"Front Cell Infect Microbiol"},{"key":"B3","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1016\/j.jaad.2016.12.043","article-title":"The burden of skin disease in the United States","volume":"76","author":"Lim","year":"2017","journal-title":"J Am Acad Dermatol"},{"key":"B4","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/j.jaci.2014.03.009","article-title":"Molecular profiling of contact dermatitis skin identifies allergen-dependent differences in immune response","volume":"134","author":"Dhingra","year":"2014","journal-title":"J Allergy Clin Immunol"},{"key":"B5","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1016\/j.jaci.2014.11.017","article-title":"Patients with atopic dermatitis have attenuated and distinct contact hypersensitivity responses to common allergens in skin","volume":"135","author":"Correa da Rosa","year":"2015","journal-title":"J Allergy Clin Immunol"},{"key":"B6","article-title":"Summary Health Statistics: National Health Interview Survey, 2018, table A-2,","year":"2018"},{"key":"B7","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.anai.2020.12.020","article-title":"Atopic dermatitis in the pediatric population: A cross-sectional, international epidemiologic study","volume":"126","author":"Silverberg","year":"2021","journal-title":"Ann Allergy Asthma Immunol"},{"key":"B8","article-title":"Asthma, Data, Statistics, and Surveillance, 2021. 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