{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T14:44:47Z","timestamp":1782398687503,"version":"3.54.5"},"reference-count":33,"publisher":"Oceanside Publications Inc.","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["allergy asthma proc"],"published-print":{"date-parts":[[2024,7,1]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> Fruit allergy usually presents with mild-to-moderate symptoms but serious systemic reactions, <jats:italic>e.g.,<\/jats:italic> anaphylaxis, may also occur.  <jats:bold>Objective:<\/jats:bold> This study aimed to examine the clinical and laboratory characteristics of patients with fruit\n allergy and fruit-induced anaphylaxis.  <jats:bold>Methods:<\/jats:bold> Patients diagnosed with fruit allergy at D\u0131\u015fkap\u0131 Hematology and Oncology Hospital and Bilkent City Hospital between January 2017 and January 2023 were included in the study. The diagnosis of anaphylaxis\n was made according to the European Allergy and Clinical Immunology Anaphylaxis Guideline.  <jats:bold>Results:<\/jats:bold> During the study period, skin-prick tests with food allergens were performed on 9432 patients in our clinic, and fruit allergy was detected in 78 patients (0.82%). Five patients\n with inaccessible medical records were excluded from the study. 40 (54.8%) were boys. The median (interquartile range) age at the onset of symptoms was 72 months (12.5\u2010144 months). Sixty-eight of the patients (93.2%) had a concomitant allergic disease, the most common of which was allergic\n rhinitis (<jats:italic>n<\/jats:italic> = 48 [65.8%]). The 73 patients had a history of reaction to 126 fruits. Twenty-five patients (19.8%) were allergic to multiple fruits. The most common fruit allergen was banana (22\/126 [17.4%]), followed by peach (18\/126 [14.2%]) and kiwi (17\/126 [13.5%]). Mucocutaneous\n findings were observed most frequently after fruit consumption (120\/126 [95.2%]). Anaphylaxis occurred in 17 patients (23.2%) with 21 fruits.The fruits most commonly associated with anaphylaxis were banana (6\/21 [28.6%]) and kiwi (6\/21 [28.6%]).  <jats:bold>Conclusion:<\/jats:bold> Fruit allergy\n generally presents with mild symptoms, e.g., oral allergy syndrome, but severe systemic symptoms, e.g., anaphylaxis, can also be observed. Kiwi and banana are the fruits that most commonly cause anaphylaxis. Although more comprehensive studies are needed to comment on the development of tolerance,\n especially in patients with anaphylaxis, responsible fruit avoidance is still the most important strategy.<\/jats:p>","DOI":"10.2500\/aap.2024.45.240027","type":"journal-article","created":{"date-parts":[[2024,7,10]],"date-time":"2024-07-10T04:33:48Z","timestamp":1720586028000},"page":"e31-e37","source":"Crossref","is-referenced-by-count":4,"title":["Fruit allergy and anaphylaxis in children: Culprit fruits and clinical findings"],"prefix":"10.2500","volume":"45","author":[{"given":"Funda","family":"Aytekin Guvenir","sequence":"first","affiliation":[{"name":"From the Department of Pediatric Allergy\/Immunology, Ankara Bilkent City Hospital, Ankara, Turkey, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeynep","family":"Sengul Emeksiz","sequence":"additional","affiliation":[{"name":"From the Department of Pediatric Allergy\/Immunology, Ankara Bilkent City Hospital, Ankara, Turkey, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sule","family":"Buyuk Yaytokgil","sequence":"additional","affiliation":[{"name":"From the Department of Pediatric Allergy\/Immunology, Ankara Bilkent City Hospital, Ankara, Turkey, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muge","family":"Toyran","sequence":"additional","affiliation":[{"name":"From the Department of Pediatric Allergy\/Immunology, Ankara Bilkent City Hospital, Ankara, Turkey, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emine","family":"Dibek Misirlioglu","sequence":"additional","affiliation":[{"name":"From the Department of Pediatric Allergy\/Immunology, Ankara Bilkent City Hospital, Ankara, Turkey, and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1355","reference":[{"key":"B1","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1159\/000375469","article-title":"Fruit and vegetable 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