{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T23:20:57Z","timestamp":1777159257105,"version":"3.51.4"},"reference-count":9,"publisher":"Oceanside Publications Inc.","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["allergy asthma proc"],"published-print":{"date-parts":[[2024,11,1]]},"abstract":"Background:<\/jats:bold> Various formulations of dog allergen extracts, including conventional dog (also known as dog epithelium) and acetone precipitated (AP) dog, have been used for skin-prick testing (SPT), with AP dog showing improved antigen content but experiencing stability issues\n due to precipitant formation. Ultrafiltered (UF) dog extract has been developed to address these concerns by offering comparable allergen content to AP dog. This study retrospectively compared UF dog with conventional dog and AP dog in SPT. Objective:<\/jats:bold> To compare the efficacy\n of UF dog extract with conventional dog and AP dog extracts in detecting dog sensitization through SPT. Methods:<\/jats:bold> Retrospective analysis of SPT results from a single U.S. allergy clinic was conducted. Tests performed between October 2022 and March 2024 were included. Primary\n and secondary outcomes were analyzed by using descriptive statistics and statistical tests. Results:<\/jats:bold> UF dog, AP dog, and conventional dog showed positivity rates of 24.2%, 23.5%, and 16.3%, respectively. UF dog demonstrated significantly higher average wheal and erythema\n sizes compared with conventional dog and AP dog, but UF dog was not statistically different from AP dog in terms of test positivity. Conclusion:<\/jats:bold> UF dog extract showed comparable number of positive tests to AP dog and a greater number of positive tests to conventional dog.\n Results of the study suggest UF dog as a viable alternative to AP dog, which offered improved stability and similar test responses. Further research with larger sample sizes is recommended to confirm these findings.<\/jats:p>","DOI":"10.2500\/aap.2024.45.240073","type":"journal-article","created":{"date-parts":[[2024,11,9]],"date-time":"2024-11-09T04:32:18Z","timestamp":1731126738000},"page":"453-455","source":"Crossref","is-referenced-by-count":3,"title":["Ultrafiltered dog allergen skin test compared with acetone precipitated and conventional dog: A retrospective study"],"prefix":"10.2500","volume":"45","author":[{"given":"Joshua","family":"Pollock","sequence":"first","affiliation":[{"name":"From the Department of Allergy and Immunology, Walter Reed National Military Medical Center, Bethesda, MD and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nora","family":"Watson","sequence":"additional","affiliation":[{"name":"Department of Research Programs, Walter Reed National Military Medical Center, Bethesda, MD"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luke","family":"Pittman","sequence":"additional","affiliation":[{"name":"From the Department of Allergy and Immunology, Walter Reed National Military Medical Center, Bethesda, MD and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Schwartz","sequence":"additional","affiliation":[{"name":"From the Department of Allergy and Immunology, Walter Reed National Military Medical Center, Bethesda, MD and"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1355","reference":[{"key":"B1","doi-asserted-by":"crossref","first-page":"366","DOI":"10.2500\/aap.2019.40.4248","article-title":"Skin testing in allergy","volume":"40","author":"Patel","year":"2019","journal-title":"Allergy Asthma Proc"},{"key":"B2","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1002\/alr.23090","article-title":"International consensus statement on allergy and rhinology: allergic rhinitis - 2023","volume":"13","author":"Wise","year":"2023","journal-title":"Int Forum Allergy Rhinol"},{"key":"B3","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1159\/000321113","article-title":"Skin prick test extracts for dog allergy diagnosis show considerable variations regarding the content of major and minor dog allergens","volume":"154","author":"Curin","year":"2011","journal-title":"Int Arch Allergy Immunol"},{"key":"B4","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaci.2008.12.780","volume-title":"Comparison of conventional and acetone precipitated dog allergen extracts in identification of dog allergy by skin prick test: American Academy of Allergy, Asthma & Immunology (AAAAI) Conference; 2009 Mar 16; Washington, DC. Penn State Hershey Allergy, Asthma and immunology","author":"Krassilnikova","year":"2009"},{"key":"B5","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1067\/mai.2001.114340","article-title":"Comparing conventional and acetone-precipitated dog allergen extract skin testing","volume":"107","author":"Meiser","year":"2001","journal-title":"J Allergy Clin Immunol"},{"key":"B6","doi-asserted-by":"crossref","article-title":"Discordance between conventional and acetone precipitated (AP) dog extract in skin prick testing.","author":"Turbyville","DOI":"10.1016\/j.jaci.2007.12.234"},{"key":"B7","journal-title":"Technical report, UF dog hair and dander extract"},{"key":"B8","doi-asserted-by":"crossref","article-title":"Characterization of commercial dog allergen extracts, including new ultrafiltered dog extract","author":"Brown","DOI":"10.1016\/j.anai.2022.08.566"},{"key":"B9","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1016\/j.jaci.2006.07.055","article-title":"Immunologic response to administration of standardized dog allergen extract at differing doses","volume":"118","author":"Lent","year":"2006","journal-title":"J Allergy Clin Immunol"}],"container-title":["Allergy and Asthma Proceedings"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ingentaconnect.com\/content\/ocean\/aap\/2024\/00000045\/00000006\/art00017","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,9]],"date-time":"2024-11-09T04:33:34Z","timestamp":1731126814000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ingentaconnect.com\/content\/10.2500\/aap.2024.45.240073"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,1]]},"references-count":9,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,11,1]]}},"alternative-id":["1088-5412(20241101)45:6L.453;1-"],"URL":"https:\/\/doi.org\/10.2500\/aap.2024.45.240073","relation":{},"ISSN":["1088-5412"],"issn-type":[{"value":"1088-5412","type":"print"}],"subject":[],"published":{"date-parts":[[2024,11,1]]}}}