{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T16:39:39Z","timestamp":1777480779975,"version":"3.51.4"},"reference-count":10,"publisher":"Oceanside Publications Inc.","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["allergy asthma proc"],"published-print":{"date-parts":[[2026,1,1]]},"abstract":"<jats:p>\n                    <jats:bold>Background:<\/jats:bold>\n                    One in five Americans turn to TikTok before calling their own physician.\n                    <jats:bold>Objective:<\/jats:bold>\n                    With social media on the rise as a source of health-related information, we aimed to investigate and evaluate popular content about mast cell activation syndrome\n (MCAS) on TikTok.\n                    <jats:bold>Methods:<\/jats:bold>\n                    Between June 14 and 16, 2024, four different MCAS-relevant phrases were searched on TikTok, and the top 50 most watched videos were analyzed independently by three subinvestigators. The global quality score (GQS) (range from 1 to 5) was applied\n to assess the value of the educational videos. The profession of the content creator, use of MCAS Vienna diagnostic criteria, association with postural orthostatic syndrome (POTS)\/Ehlers Danlos syndrome (EDS), and information trends were also analyzed.\n                    <jats:bold>Results:<\/jats:bold>\n                    The 50 most\n watched MCAS-related videos collectively had &gt; 6.5 million views, and the average number of views per video was 131,500. Most videos were created by health-care professionals (58%), including physicians (26%) and other health-care professionals (32%), whereas the minority were created by\n non\u2010health-care professionals (42%). Only one video included the MCAS Vienna criteria (2%), and 12 videos associated MCAS with POTS and\/or EDS (24%). The average GQS was 1.94 (SD 0.34). Common MCAS misinformation trends included the following: inaccuracy of symptoms, diagnostic criteria,\n triggers, and treatment options.\n                    <jats:bold>Conclusion:<\/jats:bold>\n                    Most MCAS videos on TikTok contained misinformation, did not include key diagnostic criteria, and had poor GQS. The most viewed videos were primarily created by health-care professionals. Patients and health-care providers need\n to be aware of the quality of health-care information on social media.\n                  <\/jats:p>","DOI":"10.2500\/aap.2026.47.250090","type":"journal-article","created":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T04:32:26Z","timestamp":1768019546000},"page":"e1-e3","source":"Crossref","is-referenced-by-count":2,"title":["Scroll, like, diagnose? Evaluating mast cell activation syndrome information on TikTok"],"prefix":"10.2500","volume":"47","author":[{"given":"Emily","family":"Gansert","sequence":"first","affiliation":[{"name":"From the Department of Internal Medicine, Mayo Clinic, Jacksonville, Florida;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricardo J.","family":"Estrada-Mendizabal","sequence":"additional","affiliation":[{"name":"Division of Allergy, Asthma and Clinical Immunology, Department of Medicine, Mayo Clinic, Scottsdale, Arizona; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew M.","family":"Farley","sequence":"additional","affiliation":[{"name":"Division of Allergy, Asthma and Clinical Immunology, Department of Medicine, Mayo Clinic, Scottsdale, Arizona; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dayne H.","family":"Voelker","sequence":"additional","affiliation":[{"name":"Division of Allergic Diseases, Mayo Clinic, Rochester, Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexei","family":"Gonzalez-Estrada","sequence":"additional","affiliation":[{"name":"Division of Allergy, Asthma and Clinical Immunology, Department of Medicine, Mayo Clinic, Scottsdale, Arizona; and"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1355","reference":[{"key":"B1","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1016\/j.jaip.2024.01.013","article-title":"Dilemma of mast cell activation syndrome: overdiagnosed or underdiagnosed?","volume":"12","author":"Akin","year":"2024","journal-title":"J Allergy Clin Immunol Pract"},{"key":"B2","doi-asserted-by":"crossref","first-page":"3918","DOI":"10.1016\/j.jaip.2021.06.011","article-title":"Selecting the right criteria and proper classification to diagnose mast cell activation syndromes: a critical review","volume":"9","author":"G\u00fclen","year":"2021","journal-title":"J Allergy Clin Immunol Pract"},{"key":"B3","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1016\/j.jaci.2019.08.023","article-title":"AAAAI Mast Cell Disorders Committee Work Group Report: mast cell activation syndrome (MCAS) diagnosis and management","volume":"144","author":"Weiler","year":"2019","journal-title":"J Allergy Clin Immunol"},{"key":"B4","doi-asserted-by":"crossref","first-page":"198","DOI":"10.2500\/aap.2021.42.210012","article-title":"Mast cell activation syndrome: myths and realities","volume":"42","author":"Zhang","year":"2021","journal-title":"Allergy Asthma Proc"},{"key":"B5","first-page":"345","article-title":"Lessons learned: avoiding risks when using social media","volume":"120","author":"Hennessy","year":"2023","journal-title":"Mo Med"},{"key":"B6","doi-asserted-by":"crossref","first-page":"2070","DOI":"10.1111\/j.1572-0241.2007.01325.x","article-title":"A systematic review of patient inflammatory bowel disease information resources on the World Wide Web","volume":"102","author":"Bernard","year":"2007","journal-title":"Am J Gastroenterol"},{"key":"B7","doi-asserted-by":"crossref","first-page":"e39162","DOI":"10.2196\/39162","article-title":"Quality of information in gallstone disease videos on TikTok: cross-sectional study","volume":"25","author":"Sun","year":"2023","journal-title":"J Med Internet Res"},{"key":"B8","doi-asserted-by":"crossref","first-page":"e54663","DOI":"10.2196\/54663","article-title":"TikTok as a source of health information and misinformation for young women in the United States: survey study","volume":"4","author":"Kirkpatrick","year":"2024","journal-title":"JMIR Infodemiology"},{"key":"B9","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1007\/s11882-018-0822-6","article-title":"Social media and allergy","volume":"18","author":"Dimov","year":"2018","journal-title":"Curr Allergy Asthma Rep"},{"key":"B10","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.anai.2016.01.021","article-title":"Social media and the allergy practice","volume":"116","author":"Dimov","year":"2016","journal-title":"Ann Allergy Asthma Immunol"}],"container-title":["Allergy and Asthma Proceedings"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ingentaconnect.com\/content\/ocean\/aap\/2026\/00000047\/00000001\/art00001","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T04:33:21Z","timestamp":1768019601000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ingentaconnect.com\/content\/10.2500\/aap.2026.47.250090"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,1]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1,1]]}},"alternative-id":["1088-5412(20260101)47:1L.1;1-"],"URL":"https:\/\/doi.org\/10.2500\/aap.2026.47.250090","relation":{},"ISSN":["1088-5412"],"issn-type":[{"value":"1088-5412","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1,1]]}}}