{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T00:05:23Z","timestamp":1789344323866,"version":"build-2803163510"},"reference-count":9,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Rhinol\ufffdAllergy"],"published-print":{"date-parts":[[2009,1]]},"abstract":"\n Background<\/jats:title>\n The objectives of this study were, first, to confirm the presence of multiple domains within the Sino-Nasal Outcome Test 20 (SNOT-20) using a medically treated population, and, second, to reanalyze data from this population to reveal incremental information. A prospective, randomized controlled trial was performed.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n One hundred twenty-seven adults with chronic rhinitis or rhinosinusitis symptoms were treated with nasal saline irrigation or spray. Treatment outcome was quality of life measured with SNOT-20 scores, which were reanalyzed for this study with a factor analysis. Differences in change scores were compared.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Factor analysis confirmed the presence of four domains: psychological function, sleep function, rhinological symptoms, and ear and\/or facial symptoms. At 8 weeks after randomization, saline irrigation had significant effects on the rhinological symptom (p = 0.01) and sleep (p = 0.01) compared with saline spray, but no between-group difference was seen in psychological function or ear and\/or facial symptom domains.<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Subscales identified differences in the impact of two medical interventions on chronic sinonasal symptoms. Reporting subscale scores might improve the precision of the SNOT-20 instrument, allowing discrimination between various treatments and their differential impact on sinonasal quality of life.<\/jats:p>\n <\/jats:sec>","DOI":"10.2500\/ajra.2009.23.3259","type":"journal-article","created":{"date-parts":[[2009,3,4]],"date-time":"2009-03-04T19:44:56Z","timestamp":1236195896000},"page":"40-45","source":"Crossref","is-referenced-by-count":65,"title":["Validation of the Sino-Nasal Outcome Test 20 (SNOT-20) Domains in Nonsurgical Patients"],"prefix":"10.1177","volume":"23","author":[{"given":"Melissa A.","family":"Pynnonen","sequence":"first","affiliation":[{"name":"Department of Otolaryngology, University of Michigan Health System, Ann Arbor, Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. Myra","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Center for Statistical Consultation and Research, University of Michigan, Ann Arbor, Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey E.","family":"Terrell","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, University of Michigan Health System, Ann Arbor, Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2009,1,1]]},"reference":[{"key":"bibr1-ajra.2009.23.3259","doi-asserted-by":"publisher","DOI":"10.2500\/ajr.2007.21.2960"},{"key":"bibr2-ajra.2009.23.3259","doi-asserted-by":"publisher","DOI":"10.2500\/ajr.2006.20.2907"},{"key":"bibr3-ajra.2009.23.3259","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2002.121022"},{"key":"bibr4-ajra.2009.23.3259","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2007.01482.x"},{"key":"bibr5-ajra.2009.23.3259","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2007.01.024"},{"key":"bibr6-ajra.2009.23.3259","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.133.11.1115"},{"key":"bibr7-ajra.2009.23.3259","first-page":"487","volume-title":"In Modern Factor Analysis","author":"Harman H.H.","year":"1976","edition":"3"},{"key":"bibr8-ajra.2009.23.3259","first-page":"559","volume-title":"In Multivariate Statistical Inference and Applications.","author":"Rencher A.C.","year":"1998"},{"key":"bibr9-ajra.2009.23.3259","first-page":"231","volume-title":"In Health Measurement Scales: A Practical Guide to Their Development and Use","author":"Streiner D.L.","year":"1995","edition":"2"}],"container-title":["American Journal of Rhinology & Allergy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.2500\/ajra.2009.23.3259","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.2500\/ajra.2009.23.3259","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.2500\/ajra.2009.23.3259","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T09:32:03Z","timestamp":1777368723000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.2500\/ajra.2009.23.3259"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,1]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,1]]}},"alternative-id":["10.2500\/ajra.2009.23.3259"],"URL":"https:\/\/doi.org\/10.2500\/ajra.2009.23.3259","relation":{},"ISSN":["1945-8924","1945-8932"],"issn-type":[{"value":"1945-8924","type":"print"},{"value":"1945-8932","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,1]]}}}