{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T05:21:43Z","timestamp":1778822503338,"version":"3.51.4"},"reference-count":15,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2011,5,1]],"date-time":"2011-05-01T00:00:00Z","timestamp":1304208000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Am J Rhinol\ufffdAllergy"],"published-print":{"date-parts":[[2011,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Multiple chronic rhinosinusitis (CRS) staging systems have been developed in an attempt to correlate symptoms with radiological imaging results. Currently, no perfect system exists. We sought to analyze the maxillary sinus (MS) using three-dimensional volumetric measurements and advanced high-resolution CT imaging.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We reviewed MS CT scans from 50 control subjects and 50 subjects with documented CRS involving at least one MS. The following measurements were recorded: (1) volume of MS free air, (2) MS mucosal thickening, and (3) MS lateral wall bony thickness. Average Hounsfield unit (HU) values for mucosal thickening among CRS subjects were also recorded. Values are expressed as mean \u00b1 SD and median. Values from the CRS patients were compared with healthy controls using Student's t-tests.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among controls (n = 50), volumes (mL) of right and left MS were 24.1 \u00b1 9.7 and 24.7 \u00b1 9.0, respectively. Among CRS patients (n = 50), the portion of mucosal disease to total sinus volume was 51.8% (right) and 50.7% (left). Mean bony thickness (mm) in controls was 0.98 \u00b1 0.2 (right) and 1.0 \u00b1 0.3 (left). CRS patients had significantly greater bony thickness 1.9 \u00b1 0.8 (right) and 2.0 \u00b1 0.9 (left; p = 0.0001). HU for diseased MS were 30.1 \u00b1 18.7 (right) and 35.7 \u00b1 22.1 (left).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Three-dimensional volumetric analysis combined with HU calculations and bony thickness measurements represents a new and unique way to evaluate CT scans in patients with CRS. Additional studies correlating symptoms with imaging findings as well as analysis of all paranasal sinuses is the next step toward a novel staging system.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2500\/ajra.2011.25.3605","type":"journal-article","created":{"date-parts":[[2011,5,30]],"date-time":"2011-05-30T08:34:19Z","timestamp":1306744459000},"page":"152-156","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":22,"title":["Three-dimensional Volumetric Measurements and Analysis of the Maxillary Sinus"],"prefix":"10.1177","volume":"25","author":[{"given":"Robert","family":"Deeb","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery, Henry Ford Health System, Detroit, Michigan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Preeti N.","family":"Malani","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University of Michigan Health System, and Veterans Affairs Ann Arbor Healthcare System, Geriatric Research Education and Clinical Center, Ann Arbor, Michigan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baljinder","family":"Gil","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, St. John Providence Health System, Detroit, Michigan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kourosh","family":"Jafari-Khouzani","sequence":"additional","affiliation":[{"name":"Department of Radiology, Henry Ford Health System, Detroit, Michigan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamid","family":"Soltanian-Zadeh","sequence":"additional","affiliation":[{"name":"Department of Radiology, Henry Ford Health System, Detroit, Michigan, and Control and Intelligent Processing Center of Excellence, School of Electrical and Computer Engineering, University of Tehran, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suresh","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Radiology, Henry Ford Health System, Detroit, Michigan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark A.","family":"Zacharek","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery, University of Michigan Health System, Ann Arbor, Michigan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2011,5,1]]},"reference":[{"key":"bibr1-ajra.2011.25.3605","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2009.23.3260"},{"key":"bibr2-ajra.2011.25.3605","first-page":"183","volume":"31","author":"Lund V.J.","year":"1993","journal-title":"Rhinology"},{"key":"bibr3-ajra.2011.25.3605","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-5998(97)70129-3"},{"key":"bibr4-ajra.2011.25.3605","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.1994.tb01232.x"},{"key":"bibr5-ajra.2011.25.3605","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2001.116779"},{"key":"bibr6-ajra.2011.25.3605","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-59980223295-7"},{"key":"bibr7-ajra.2011.25.3605","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2010.24.3430"},{"key":"bibr8-ajra.2011.25.3605","author":"Henry Ford Health System Radiology Research.","journal-title":"Henry Ford Health System, October 25, 2007."},{"key":"bibr9-ajra.2011.25.3605","author":"Meriam Webster, 2010.","journal-title":"Merriam-Webster Online Dictionary."},{"key":"bibr10-ajra.2011.25.3605","first-page":"627","volume-title":"In Digital Image Processing.","author":"Gonzalez R.C.","year":"2008"},{"key":"bibr11-ajra.2011.25.3605","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2005.07.007"},{"key":"bibr12-ajra.2011.25.3605","doi-asserted-by":"publisher","DOI":"10.3109\/00016489409124322"},{"key":"bibr13-ajra.2011.25.3605","doi-asserted-by":"publisher","DOI":"10.1097\/00020840-200202000-00013"},{"key":"bibr14-ajra.2011.25.3605","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199804000-00008"},{"key":"bibr15-ajra.2011.25.3605","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2009.23.3300"}],"container-title":["American Journal of Rhinology &amp; 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