{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T20:20:18Z","timestamp":1785529218976,"version":"3.56.0"},"reference-count":22,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Am J Rhinol\ufffdAllergy"],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Differential diagnosis between ragweed and mugwort pollen allergy represents a large clinical problem in areas where both plants are present. The aim of this study was to investigate ragweed- and mugwort-sensitized patients to identify specific IgE reactivity profiles. Results were correlated to clinical findings such as medical history and health-related quality of life (HRQL).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Seventy-four patients with allergic rhinoconjunctivitis between July and October were examined and underwent in vivo tests (skin-prick test [SPT] and nasal provocation). Sera were evaluated for IgE reactivity to mugwort and ragweed pollen extracts, major (Art v 1; Amb a 1) and minor (profilin and calcium-binding protein) allergens. HRQL was evaluated using a standardized questionnaire.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Seventy-one patients revealed positive SPT reactivity against mugwort and 60 patients against ragweed extracts. Of these patients, 74 revealed IgE antibodies against mugwort extracts, whereas anti\u2013Art v 1 antibodies were detectable in 50 individuals. Fifty-five patients showed IgE antibodies against natural ragweed extracts; anti\u2013Amb v 1 antibodies were detected in six cases only. Using standardized clinical history and HRQL questionnaires we were not able to detect any differences within different reactivity patterns.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Within the investigated population of 74 weed-allergic patients the prevalence of true mugwort and ragweed sensitization can be calculated as 68 and 8%. High prevalence of ragweed sensitization when testing with full extracts can be explained by cross-reactivity between other weeds, e.g., mugwort rather than cosensitization. Differences in medical history and HRQL between different reactivity patterns were not detectable.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2500\/ajra.2012.26.3698","type":"journal-article","created":{"date-parts":[[2012,2,27]],"date-time":"2012-02-27T12:26:34Z","timestamp":1330345594000},"page":"31-35","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":17,"title":["IgE Reactivity Patterns in Patients with Allergic Rhinoconjunctivitis to Ragweed and Mugwort Pollens"],"prefix":"10.1177","volume":"26","author":[{"given":"Martin","family":"Canis","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, University of Goettingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sven","family":"Becker","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, University of Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moritz","family":"Gr\u00f6ger","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, University of Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias F.","family":"Kramer","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, University of Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2012,1,1]]},"reference":[{"key":"bibr1-ajra.2012.26.3698","first-page":"417","volume":"75","author":"Frenz D.A.","year":"1995","journal-title":"Ann Allergy Asthma Immunol"},{"key":"bibr2-ajra.2012.26.3698","doi-asserted-by":"publisher","DOI":"10.1159\/000108134"},{"key":"bibr3-ajra.2012.26.3698","first-page":"323","volume":"27","author":"Dechamp C.","year":"1995","journal-title":"Allerg Immunol (Paris)"},{"key":"bibr4-ajra.2012.26.3698","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.1997.tb00672.x"},{"key":"bibr5-ajra.2012.26.3698","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2009.02093.x"},{"key":"bibr6-ajra.2012.26.3698","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2007.01393.x"},{"key":"bibr7-ajra.2012.26.3698","first-page":"267","volume":"5","author":"Treudler R.","year":"1995","journal-title":"Allergo J"},{"key":"bibr8-ajra.2012.26.3698","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-2776(08)60319-3"},{"key":"bibr9-ajra.2012.26.3698","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2004.00464.x"},{"key":"bibr10-ajra.2012.26.3698","doi-asserted-by":"publisher","DOI":"10.1096\/fj.02-0472fje"},{"key":"bibr11-ajra.2012.26.3698","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2003.1495"},{"key":"bibr12-ajra.2012.26.3698","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(98)70384-7"},{"key":"bibr13-ajra.2012.26.3698","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2003.1683"},{"key":"bibr14-ajra.2012.26.3698","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(96)80187-4"},{"key":"bibr15-ajra.2012.26.3698","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2001.115566"},{"key":"bibr16-ajra.2012.26.3698","doi-asserted-by":"publisher","DOI":"10.2500\/aap.2009.30.3230"},{"key":"bibr17-ajra.2012.26.3698","doi-asserted-by":"publisher","DOI":"10.1055\/s-2003-38411"},{"key":"bibr18-ajra.2012.26.3698","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/S0091-6749(97)70016-2","volume":"99","author":"The use of standardized allergen extracts.","year":"1997","journal-title":"J Allergy Clin Immunol"},{"key":"bibr19-ajra.2012.26.3698","doi-asserted-by":"publisher","DOI":"10.1023\/A:1007603321556"},{"key":"bibr20-ajra.2012.26.3698","doi-asserted-by":"publisher","DOI":"10.1515\/CCLM.2006.024"},{"key":"bibr21-ajra.2012.26.3698","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.1994.9.3.213"},{"key":"bibr22-ajra.2012.26.3698","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.2006.02477.x"}],"container-title":["American Journal of Rhinology &amp; 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