{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:21:32Z","timestamp":1777386092868,"version":"3.51.4"},"reference-count":24,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Am J Rhinol\ufffdAllergy"],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The aim of this study was to describe treatment results in patients with sinonasal mucosal melanomas (SMMs) and to compare three different classification staging systems.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>From 1988 to 2013, we performed a retrospective study of 20 patients with primary sinonasal melanomas. The median age at diagnosis was 71 years. There were 10 males and 10 females.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Nine SMMs (45%) were originated in the ethmoidal sinus complex, four (20%) in the inferior turbinate, three (15%) in the nasal septum, two (10%) in the maxillary sinus, and two (10%) in the nasal vestibule. Local recurrence was diagnosed in eight patients (40%), and six out of 20 patients (30%) developed distant metastasis during the course of their disease. The adjusted survival rates at three and five years were 47% and 34%, respectively. The adjusted three-year survival rate according to the sinonasal staging system 7th edition for SMM (TNM-SMM) was 60% in T3 stage, 50% in T4a stage, and 34% in T4b stage (p = 0.05). According to Thompson's staging system, survival was 33% for group one, 58% for group two, and 0% for group three (p = 0.006). With the sinonasal staging system 7th edition for carcinoma (TNM-CAR) survival was 33% in T1, 100% in T2 and T3, 0% in T4a, and 34% in T4b (p = 0.006).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our experience confirms the distribution of patients according to survival rates was better with the TNM-SMM than with Thompson's or the TNM-CAR systems.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2500\/ajra.2015.29.4128","type":"journal-article","created":{"date-parts":[[2015,1,14]],"date-time":"2015-01-14T19:29:30Z","timestamp":1421263770000},"page":"e37-e40","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":16,"title":["Management of Sinonasal Mucosal Melanomas and Comparison of Classification Staging Systems"],"prefix":"10.1177","volume":"29","author":[{"given":"Juan R.","family":"Gras-Cabrerizo","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\/Head and Neck Surgery, Hospital de la Santa Creu i Sant Pau, Universitat Aut\u00f2noma de Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xavier","family":"Le\u00f3n-Vintr\u00f3","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\/Head and Neck Surgery, Hospital de la Santa Creu i Sant Pau, Universitat Aut\u00f2noma de Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margarita Majem","family":"Tarruella","sequence":"additional","affiliation":[{"name":"Department of Oncology, Hospital de la Santa Creu i Sant Pau, Universitat Aut\u00f2noma de Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriel Pedemonte","family":"Sarria","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\/Head and Neck Surgery, Hospital de la Santa Creu i Sant Pau, Universitat Aut\u00f2noma de Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolina Bothe","family":"Gonzalez","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\/Head and Neck Surgery, Hospital de la Santa Creu i Sant Pau, Universitat Aut\u00f2noma de Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joan R.","family":"Montserrat-Gili","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\/Head and Neck Surgery, Hospital de la Santa Creu i Sant Pau, Universitat Aut\u00f2noma de Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherina","family":"Kolanczak","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\/Head and Neck Surgery, Hospital de la Santa Creu i Sant Pau, Universitat Aut\u00f2noma de Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Humbert","family":"Massegur-Solench","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\/Head and Neck Surgery, Hospital de la Santa Creu i Sant Pau, Universitat Aut\u00f2noma de Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2015,1,1]]},"reference":[{"key":"bibr1-ajra.2015.29.4128","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2011.10.004"},{"key":"bibr2-ajra.2015.29.4128","doi-asserted-by":"publisher","DOI":"10.3109\/02841869709100731"},{"key":"bibr3-ajra.2015.29.4128","doi-asserted-by":"crossref","first-page":"2215","DOI":"10.1002\/cncr.24976","volume":"116","author":"Moreno 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